Penicillins Flashcards

1
Q

What are the typical doses for Amoxicillin

A

Moxatag: 775mg QD Amoxil: 250-500Q8-H, 500-875 Q12H

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2
Q

What are the brand names of amoxicillin

A

Moxatag Amoxil

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3
Q

What is the H.pylori treatment dose for amoxicillin

A

H.pylori treatment: 1g BID

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4
Q

What is the prophylactic dose of amoxicillin for infective endocarditis?

A

IE prevention: 2g 30-60 min before procedure

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5
Q

Amoxicillin is the DOC for what conditions?

A

DOC: acute otitis media, pregnancy, H.pylori, IE prophylaxis

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6
Q

What are the brand names of ampicillin

A

Ominipen, Polycillin, Prinicipen

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7
Q

What are the oral and IV dose of ampicillin

A

PO- 250-500mg Q6H

IV- 1-2g Q4-6H

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8
Q

What are the typical doses of Amoxicillin + Clavulanate?

A

Augmentin: 250-500mg q8H, 875-1000mg Q12H

Augmentin ES-600 Augmentin XR Amcolan

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9
Q

What are the stability requieremtns for Ampicilin

A

only in NS

stable for 8H @ room temp

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10
Q

Generic name for Unasyn is:

A

Ampicillin + Sulbactam

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11
Q

B-lactamase inhibitors

A

sulbactam

clavulanate/ clavulanic acid

tazobactam

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12
Q

Penicillins with B-lactamase inhibiting activity

A

Augmentin (amoxicillin + calvulanate)

Unasyn (ampicillin + sulbactam)

Zosyn (pipercillin + tazobactam)

Timentin (ticarcillin + calvulanic acid)

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13
Q

what is the typical dose of Penicillin?

A

Pen VK PO: 125-500mg Q6-8H

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14
Q

Penicillin G Benzathine

A

Bicillin L-A

Bicillin C-R: penicillin G benzathine & penicillin G procaine IM: 1.2-2.4MU x 1 ONLY

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15
Q

Penicillin G Aqueous

A

Pfizerpen G IV: 2-3 MU Q4-6H

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16
Q

Pseudamonal penicillins

A

Pipercillin & ticarcillin

17
Q

Antistaphlococcal penicillins

A

Nafcillin Oxacillin Dicloxacillin

18
Q

Penicillins w/o renal dose adjustments

A

Nafillin Oxacillin Dicloxacillin

19
Q

Nafcillin

A

IV: 1-2g Q4-6H -is a vesicant→ use cold pack & hyaluronidase injection for extravasation, administer via central line to avoid

20
Q

Ticarcillin + clavulanic acid

A

Timentin= 3g ticarcillin + 0.1g clavulanic acid 3.1g Q4-6H

21
Q

Piperacillin + tazobactam

A

Zosyn = 3g pipercillin + 0.375g tazobactam IV: 3.375 -4.5g Q6-8H

22
Q

Penicillin Antibiotics

A

Inihibit bacterial cell wall synthesis by binding to PBPs -Time dependent killing T>MIC -Bactericidal *except agains Enterococci where aminioglycoside must be added -hydrophilic