PENICILLINS Flashcards
Who discovered penicillins and in which year
Alexander Fleming in 1929
Structure of penicillins
A thiazolidine ring attached to a β-lactam ring (B) that carries a secondary amino group (RNH–)
Classes of penicillins
Natural penicillins
Antistaphylococcal or Penicillinase-resistant penicillins
Aminopenicillins or Broad spectrum penicillins
Extended spectrum penicillins or Antipseudomonal penicillins
Penicillin plus beta lactamase inhibitors
Examples of natural penicillins
Benzyl penicillin (Pen G)
Procaine penicillin
Benzathine penicillin
Phenoxymethyl penicillin (Pen V)
Antistaphylococcal penicillins
methicillin
nafcillin
oxacillin
cloxacillin
dicloxacillin
Flucloxacillin
Extended spectrum penicillins
Carboxypenicillins
Ueridopenicillins
Examples of aminopenicillins
Amoxicillin
Ampicillin
Examples of ureidopenicillins
Mezlocillin
Azlocillin
Piperacillin
Apalcillin
Examples of carboxypenicillins
Cerbenicillin
Ticarcillin
Temocillin
Examples of penicillin plus beta lactamase inhibitors
Amoxicillin-clavulanic acid
Ticarcillin-clavulanic acid
Ampicillin-sulbactam
Piperacillin-tazobactam
Prodrugs of ampicillin
Bacampicillin
Pivampicillin
Talampicillin