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Pharmacology Class Tuqa > Pen > Flashcards

Pen Flashcards

1
Q

Penicillin اي عالم اكتشفه

وعلى اي بكتريا

A

Alksander Fleming,staphylococcus

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2
Q

Penicillin can’t cross BBB

A

In normal condition but in meningitis can cross

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3
Q

Penicillin ionized or nonionized

A

Pencilin nonionzide outside the body

When enter the body become ionized

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4
Q

Which defrent betwen normal artery and cerebral artery

A

Normal artery contained poors can cross the fluid

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5
Q

Why Penicillin can cross the placenta but not teratogenic ¿

A

Because the fetal tissue absent transpeptidase enzyme pBP

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6
Q

Can retentions penicillin long time and not excretion

A

By giving probenecid inhibit excretion

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7
Q

Type of penicillin

A

1-benzylpeniciline (penicillinG)and related drug
2-antistaph penicillin
3-Extended spectrum penicillin
4-antipseudomonal penicillin

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8
Q

Which advantage and disadvantage of benzilypeniciline

A 
Advance 
1-streptococcus 
Stapheloccocase
Pneumonia 
ذولي تلاثتهم يكونونgram positive 
Sephalus 
Genase 
ذولي gram negative 
 هذا ينقاس بوحده الكونت لان يكون طبيعي

Disaadvantage
اول شي مينأخذoral لان يتأثر بلphمالت المعده
Intramuscular by 3-10time day
Spectrum of it narrowed

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9
Q

Procaine

A

Local ansethesia when driving to penicillin 24hour

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10
Q

Penzethine penciline

A

ننطق بلعضله كل ٣اسابيع حتى ميجيهم recurrent tonsillitis

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11
Q

Amoxicillin with clavulanic acid

A

=Co amoxiclave produce broaded spectrum

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12
Q

Amoxicillin concentration in

A

Bile effect liver disease and tophy

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13
Q

Ambicilin more active

A

Inshigula and influenza

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14
Q

Proimpiciline pivimpeicilin and talaimpicilin

A

More absorbed in blood and has no effect in the bectria flora

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15
Q

Which better absorbed impicilin or amoxicillin

A

Amoxicillin is better absorption and penetration than ampicillin

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16
Q

Aminoglycoside

A

Don’t cross BBB but can cross placenta

لهذا احنه مننطي للمرأه الحامل

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17
Q

Neomycin

A

Surgical in intestine oral high does ينطي لجراح علمود يعقم الامعاء

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18
Q

Benzyle penicillin

A

Treatment gram positive cocci streptococcus,staphylococcus,pnuemcocci,gram negative cocci gonococci ,meningococcus ,urinary tract infections

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19
Q

Vancomycin treatment +؛-bectria

A

Gram positive

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20
Q

Vancomycin

A

Don’t get orally

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21
Q

Red man syndrome

A

Caused by vancomycin because release histamine which cause rash skin

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22
Q

High dose of vancomycin can cause

A

Deafnease because injury in8nerve ,nephrotoxity,thrombonephlitic

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23
Q

Bactriacin

A

Inhibit building peptidoglycan block the active against positive bacteria

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24
Q

Bactricine in skin infection

A

Neomycins And polymixine

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25
Q

Macrolide

A

Erythromycin,clerthromycin,azithromycin,roxithromycin

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26
Q

Macrolid

A

Act on 50s protein synthesis in small dose bactriostatic,in high dose bactriocidal

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27
Q

Erythromycin

A

Absorption effected by food and Hcl

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28
Q

Macrolid

A

Macrolid can penetrate organ tissue and placenta and small amounts penetrate csf

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29
Q

Arethromycin andazithromycin

A

Macrophages and nuatrophil and lung tissue

30
Q

Macrolid execurtion and concentration

A

In liver bile

31
Q

Clindomycine

A

Treatment of acne ,can penetrate bone and joint

32
Q

Aminoglycoside

A

30s protein synthesis irreversible bond

better given as single large dose

33
Q

Aminoglycoside

A

Gram negative aurobic

34
Q

Aminoglycoside

A

Narrow spectrum

35
Q

Aminoglycoside +penicillin

A

Synergism because penicillin facilated Aminoglycoside to enter

36
Q

Aminoglycoside absorption

A

Not absorbed orally

37
Q

Chloramphenicol

A

Gray baby syndrome

38
Q

Function of GH

A

1-increase protein synthesis
2-increase free fatty acid in blood
3-decrease utilizing of glucose increase conservation of carbohydrates

39
Q

Panhypopitutarsim

A

Decrease level all hormon of pituitary ,don’t developed sexual

40
Q

Dwarfism

A

Def. In GH

41
Q

Gintisim

A

Executive of GH

42
Q

Deference between duration ,t1/2

A

T1/2 الزمن الي يبقى بي الدوا بالبلازما

Duration الزمن الي يبقى بي الدم بالانسجة

43
Q

Floroqunalin

A

كلهم يعالجون uti
ماعدا
Moxifloxacin

44
Q

Toboisonorize enzyme

A

HelpDNAto relax

45
Q

Floroqunoline

A

Bacteria cidal

46
Q

Fluroqunolin uses

A 
1-uti
2-RTI
3-osteomilites
4-meningitis 
5-atypical
صحصح التهاب السحايا راح نعالجه بصوره اساسيه عن طريق بينسلين بس المرضى الي عدهم حساسيه منه ومن كيفلوسبورين راح نجي ونستخدمه  فلوروكينولون 
Atypical نسخدم بصوره اساسيه 
Macrolid 
بس المريض الي عنده حساسية منه نسخدمله
47
Q

Cause of repture tendon Achilles

A

I ceprofloxoci

48
Q

Floroqunolin,Macrolid

A

⬆️QT interval

49
Q

Hypothyroidism,maxidema

A

T3;T4 decrease TSH ⬆️

Cold ,fatigue ,depression

50
Q

T4,T3

A

T4 7day

T3 1day

51
Q

Sulfoamide

A

كلهم نفس الشي ماعدا انو اكو اختلاف بلفارماكاينتك

52
Q

Kerniktrase

A

Sulfonamide

In the baby below 2year blirubine pass bbb

53
Q

Sulfonamid

A

Teratogenic

54
Q

Any drug inhibit folic acid

A

Megaloplastic anemia,neural tube effect

55
Q

Metronidazole don’t use to treatment uti بلرغم

انو ٦٠٪؜من عنده ينزل بدون تغير

A

Because this drug specialised anaerobic Bactria and UTI erobic Bactria

56
Q

Short acting penicillin

A

Benzyle penicillin

57
Q

Methicillin, cloxacillin, dicloxacillin, flucloxacillin, and nafcillin]

A

They are effective against p-lactamase producingStaphylococci.

58
Q

Penicillin high dose

A

Neurotoxicity,seizure,renal failure

59
Q

Naficilin

A

Neutropenia, thrombocytopenia,

60
Q

Methecilin

A

Interstitial nephritis,

61
Q

Coamxicalve,

A

Cholistatic jaundice

62
Q

Some organ receive single supply of ANS

A

Suprarenal gland ,blood supply,sweat gland

63
Q

Systole ,dystole

A

S CO

Dystole pr

64
Q

Personal متنرفز والعصبي

A

نعطي الفا 2

65
Q

Beta1

A

Found in kidney and hearts

66
Q

B3

67
Q

Beta2

A

الطيبه مالها اثار جانبيه 🤍📝

68
Q

Penzodiyzabine

A

اي شخص تسمم بدوا cns stimulation

69
Q

Migraine

A

صداع نصفي

70
Q

Corenary artery

A

The only artery filled in dystole

71
Q

Superior mesntric ,splanchnic

A

Portal veins

Pharmacology Class Tuqa (3 decks)

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