Pelvic Masses Flashcards
List the Benign uterine masses?
Uterine fibroids
Adenomyosis
Nabothian cyst
Cervical polyp
Endometrial polyps
What is a Uterine Fibroid?
It is a benign tumor of uterine smooth muscle
When do uterine fibroids regress and why?
- After Menopause
-Because of the reduction in estrogen levels
What are the risk factors for uterine Fibroids?(7)
-Age
-Early menarche
-Family history/Genetics
-Obesity/overweight/high BMI
-Hormonal Contraceptives
- Black
-Smoking
What are the types of fibroid?
-Submucosa
-Subserosa
-Intramural
Describe how to classify Fibroids?
REFER
What are the secondary changes a fibroid undergoes?
-Degeneration
-Hyaline
-Cystic
-Calcification
-Infection and abscess
-Necrobiosis
-Sarcomatous Change
What is Hyaline degeneration?
- Smooth muscles replaced by fibrous connective tissues
-Scattered islands of muscle cells are found intact in broad expanses of hyaline degeneration.
Describe a cystic degeneration?
An extension of hyaline degeneration with liquefaction of some areas of the fibroid and cyst formation.
Describe Calcification Degeneration?
Usually occurs after menopause/age occurs when there reduced blood flow to the fibroid which causes ischemia and tissue death and as result calcification occurs as part of the healing process.
Which fibroids usually undergo Infection and abscess formation? What does it usually follow?
-Submucous Fibroid
-Following a septic abortion or tumor
Which type of Fibroid does necrobiosis affect?
Pedunculated Subserous Fibroids
Describe red generation/Carneous Degeneration?
This a type of degeneration occurs normally during pregnancy via a couple of mechanism.
-As the uterus gets bigger there is venous obstruction and this leads to a hemorrhagic infarction resulting in ischemia and necrosis of the fibroid. The necrotic tissue triggers an inflammatory reaction and starts to look like an infection.
-this results in pain, fever.
What happens in a sarcomatous change during degeneration?
Malignant change in fibroids
What is the clinical presentation of uterine fibroids?
Abnormal vaginal bleeding
Slight Dysmenorrhea
Dyspareunia
Pelvic pain(though not a significant factor)
Pressure symptoms-Constipation, urgency, frequency
What investigations are done for someone suspected of having a Fibroid?
Bloods
FBC
Urine - pregnancy test
Imaging
Pelvic ultrasound (transvaginal vs transabdominal)
Hysteroscopy
Hysterosalpingography
MRI –provide detailed image (size, location and number)
What is the definitive management for Fibroids?
Myomectomy
Hysterectomy
Uterine artery embolism
What symptomatic management is given to treat fibroids?
NSAIDs
Antifibrinolytics- Tranexamic acid
Hormonal therapies
Combined oral contraceptives
Progestin-releasing intrauterine device
Gonadotropin-releasing hormone agonists (Leuprolide, goserelin
When is a myomectomy considered?
When fertility is a concern.
What are the complications of a Fibroid?(7)
Myomectomy
Hysterectomy
Uterine artery embolism