Peds I Flashcards
This instrument should always be used in Pediatrics:
- Detects airway compromise
- Obstruction
- Heart rate
- RR
- Precordial or esophageal stethoscope
Describe how to calculate a child’s weight?
- 50th percentileweight (kg)= (Age X 2) + 9
What correlates with intracranial volume and brain weight?
- Head circumference
What assessment finding may signal abnormal brain development and should alert the anesthesia provider to neurological problems?
- Abnormally large or small head
For how long is head circumference larger than thorax/
- First 6 months of life
What is a common cause of a large head in pediatrics?
- Hydrocephalus
What is a common cause of a small head in pediatrics?
- Craniosynostosis
- Abnormal brain development (premature closing of sutures)
What is the anesthesia provider looking for when assessing the anterior fontanel?
- Dehydration (sunken fontanel)
- Bulging (hydrocephalus, infection, hemorrhage, increased PaC02)
When does the anterior fontanel close?
- 9-18 months
- Posterior closes by 4 months
When does the first tooth come in?
- 6 months
- Normally lower incisor
When do deciduous teeth come in?
- 28 months
When do permanent teeth come in?
- 6 years
In what age of children is it appropriate to check for loose teeth?
- 5-10 years
- Careful with DL and placement of OPA
What is the appropriate intervention if a pediatric patient has very loose teeth?
- Tell parents that teeth will be removed before DL tp avoid aspiration
- Save tooth for the tooth fairy
What is the water content of a fetus?
- 90%
What is the water content of a preterm patient?
- 80%
What is the water content of a Full-term patient?
- 70%
What is the water content of a 6-12-month-old pediatric patient?
- 60%
- Adult levels at 1 y/o
What is the effect of a greater volume of distribution in drug administration?
- An increased volume of distribution
- Larger dose for loading dose but increased sensitivity. Titrate carefully
- Pediatrics have increased chest wall compliance, but the risk of lung over-expansion and apnea is increased due to what physiologic finding?
- Pliable ribs
Why are pediatrics more prone to desaturation?
- Smaller airways
- Reduced number of alveoli
- Less gas exchange area
- Less lung tissue compliance (less snap back)
- Higher closing volumes (closing capacity approaches tidal volume)
- Small airways collapse at higher volume (closing capacity greater than residual volume)
What is a consequence of the reduced FRC in pediatrics?
- Increased chance for alveolar collapse
- No gas exchange
- The relative increase of intra-abdominal contents
What is the oxygen consumption rate in pediatrics?
- 6-8 cc/kg/min
- 3-4 cc/kg/min in adults
- Twice as much as adults!
When is RSI utilized in pediatrics?
- Rarely
- Pyloric stenosis
- Small bowel obstruction
What is the lung volumes in pediatrics?
- ## Total lung capacity decreased because of LARGER residual volume
What is the lung capacity of pediatric patients compared to adults?
- Smaller
- 160 mL in peds
- 6 L in adults
What is the FRC status of a newborn?
- Decreased due to LARGER residual volume
- Apneic lung volume less than FRC
- Smaller store of 02 to draw from when apneic
Pediatric lung volumes are disproportionately _______?
- Small relative to body size
What is the most important factor in airway flow resistance?
- Poiseuille’s Law
- Change in the radius of the tube is inversely proportional to the resistance to the 4th power
- Ex. inflammation, secretions increase resistance
What is airways resistance of the newborn?
- 19-28 cmH20/L/sec
- 2 cmH20/L/sec in adults
- Central airway resistance increased until 5 y/o
What is a consequence of the immature tracheal cartilage of the neonate?
- Compliant
- Collapse can occur w/ inspiration or expiration
Decreased pulmonary gas diffusion of the pediatric patient is a consequence of what physiologic finding?
- Small surface area
- Diffusion capacity increased w/ age
Venous and oxygenated mixing in an R-L shunt is described as what in the neonate?
- Venous admixture
- Higher in infants
What is a consequence of the immature neonatal myocardium and how does it compensate?
- Less organized myocytes
- 30% Contractile elements vs. 60% in adults
- Dependent on the influx of Ca++ to initiate and terminate contraction
- Watch for decreased Ca++ w/
- Gas will decrease HR, and thus CO and then SVR/BP
What is a consequence of the low compliance of ventricles?
- Fixed SV
- CO is HR dependent
Why is the neonate prone to Bradycardia?
- PNS more mature than SNS and dominant in utero
- Systemic vascular tone is low up to 8 y/o
- Caudal/epidural block will not affect BP
What is mean HR at birth?
- 120
What is mean HR @ 1 month?
- 160
What is mean HR in adolescents?
- 75
What level of bradycardia do you treat in the infant? Toddler? Adolescent?
- 100
- 80
- 60
How do children often respond to noxious stimuli?
- Bradycardia
What is the hallmark of intravascular fluid depletion in infants?
- Hypotension without tachycardia
- Consider hypocalcemia and corrected
How much oxygen does the neonatal brain consume relative to adults?
- 50% greater than adults
- Cerebral blood flow greater by 50-70% from 6 months to three years
What neonatal problem is caused by:
- hypoxia
- fluid loss
- hypovolemia
- Anaphylaxis
- Vagal response
- Hyperkalemia, and how does it manifest?
- Bradycardia Hypotension Syndrome (BHS)
- 40% decrease in HR and BP
- Systolic arterial circulation closely related to circulating blood volume (BP good guide for the adequacy of blood replacement)
What is the dose of fluid replacement in PALS protocol?
- 10-20 mL/kg
What are the PALS, NRP epinephrine doses?
- 0.01 mg/kg- 0.03 mg/kg
- 5 mcg/kg also listed
When does normal kidney function present in pediatrics? What are their GFR levels? What effect does this have physiologically?
- 6 months, adult levels at 2 years
- GFR 15-30% adult values at one year
- Negatively affects neonatal excretion of saline, water loads, and drugs
- Metabolic acidemia, and a reduced renal tubular threshold for sodium bicarbonate
What is urine osmolality in the neonate?
- 700-800
- 1300-1400 in adults,
- Limited urine concentrating ability (also prolongs the duration of action)
- Concentrating ability matures at 3-5 weeks of age
- Decreased response to ADH
- Homeostatic mechanisms normal at one year
What can the low GFR in neonates be attributed to?
- Low systemic BP and high renal vascular resistancve
- Less blood flow
What is the most important organ to eliminate water-soluble drugs and metabolites?
- Kidneys
What are the differences in the neonatal liver compared to the adult?
- Increased total body water
- Reduced plasma protein (more free drug)
- Total protein and albumin not normal until 10-12 months
- It takes years for CYP-450 enzymes to mature
- Minimal glycogen stores
- Use an isotonic balanced salt solution for fluid resuscitation
How much weight does a neonate lose in the first few days of life?
- 5-15% of body weight
- Due to isotonic water loss
What are fluid requirements in the neonate based on?
- Weight
- U/O
- Serum Na+ levels
Describe glucose treatment in the hypoglycemic neonate?
- Should not go below 45 mg/dL in the first few hours of life
- D10W is treatment
- Bolus 2-4 mL/kg
- Continuous infusion 4-6 mg/kg/min (mL?)
What is the primary serum protein in fetal life?
- Alpha fetoprotein
- Albumin by 6-12 months (synthesis begins at 3-4 months)
What fluids do you hang for infants? Young children?
- Buretrol w/ 250 mL
- Young children (500 mL IVF, Use 1L, avoids accidental fluid overload)
- Non-glucose-containing fluid unless < 6 months, LR
- No NS, hyperchloremic metabolic acidosis
What is a consequence of the low albumin levels in the neonate?
- Clotting factors low in the first few days of life
- Drug metabolism not effective in the first few days of life (less drug)
- Less protein binding, more free drug
- Normal liver metabolism by 4-6 months
What is a consequence of the breakdown of red blood cells and impaired conjugation by the liver?
- Increased bilirubin
- Jaundice
What is a consequence of the immature pharyngoesophageal sphincter in the neonate?
- Frequent regurgitation, 40% of newborns
- Lower Esophageal Sphincter pressures normalize after 3-6 weeks
What GI issue is associated w/ Apnea and Bradycardia?
- GERD
What endocrinologic condition is common in neonates undergoing elective surgery and GA?
- Hyperglycemia (may be caused by surgical stress, lipid infusions, glucose solutions, hypoxemia, sepsis)
- Infants given glucose-containing solutions to avoid hypoglycemia
- Check BS intra-op