peds gi disorders 1 test 2 Flashcards
(Hypertrophic) Pyloric stenosis causes
Incomplete maturation of nerve fibers to pylorus
Mechanical trauma from stomach contents resulting in pyloric muscle hypertrophy
Develops after birth
Associated with some genetic syndromes: Apert, Zellweger, trisomy 18
t/f Females with pyloric stenosis have a 4x greater chance of having a child with the disease
true (this was one of the first questions I asked my wife. I aint got time for that)
t/f Exposure to macrolide antibiotics (for treatment/ prophylaxis of pertussis) may increase risk.
true!
presentation of pyloric stenosis
Non-bilious emesis that becomes progressively forceful
Vomiting, intermittent to start
Anxious to feed after emesis
Projectile vomiting as disease progresses
age range for pyloric stenosis
Range: Birth- 3 months
complication of pyloric stenosis
Dehydration, depending on time to diagnosis
exam findings for pyloric stenosis
Anxious, hungry appearing
Dehydrated, malnourished – in advanced disease
Palpable pylorus (described as an “olive”)
Firm, mobile mass, olive shaped and located above and to the right of the umbilicus
Visible gastric peristalsis
Jaundice is commonly present
first line imaging for pyloric stenosis
US (Merica!) 95% sensitivity
if you don’t do an US and you do a barium upper GI exam what are you looking for
string sign- elongated pyloric channel
shoulder sign- bulge of the pyloric muscle in to the antrum
what lab finding will you see with pyloric stenosis
Met B will demonstrate a hypochloremic metabolic alkalosis
due to loss of hydrogen ions and chloride from emesis
how do you manage pyloric stenosis
Rehydration/ correction of electrolytes (may present with alkalosis secondary to vomiting)
Surgical consultation
what is celiac disease
autoimmune disease
Gluten protein sensitivity
Wheat, barley, rye, less commonly oats
what does celiac disease cause
Chronic inflammation of the small intestine
what antibody is present in celiac disease
Anti-TG2 antibodies present
what is the classic presentation of celiac disease
after the introduction of gluten containing foods:
Chronic diarrhea,
abdominal distention, irritability,
anorexia,
vomiting and poor weight gain
stops with a gluten free diet,
starts with re-introduction of gluten
what is the common (it is atypical) presentation of celiac disease
minor GI issues
low height and weight increase
anemia from iron deficiency (not responsive to iron sups) (teeners)
arthritis, bone issues
celiac disease PE findings
Bloating of the abdomen
Dental enamel hypoplasia – rare but highly specific when present
Muscle wasting
lab findings for celiac disease
IgA anti-TG2
D-AGA
steatorrhea
Hypoproteinemia
Anemia (low MCV-iron def)
(there is so much about celiac disease wtf!) what do you see on bowel biopsy
Villous atrophy with hyperplasia of the crypts
Abnormal surface epithelium
(marsh grading system)
what does the marsh grading system look at
Intraepithelial lymphocytes
Crypt hyperplasia
Villi
what is intussusception
segment of intestine telescopes into the adjoining intestinal lumen, causing bowel obstruction.