Peds/fetal GI Flashcards
- What is the first DDx for a pancreatic tumour in the 1st decade of life?
- What does it look like?
- pancreatoblastoma
- large w/calcs & liver mets.

- What part of the duodenum is narrowed w/annular pancreas?
- 2nd.
Neonatal low/distal bowel obstruction: megacystis microcolon intestinal hypoperistalsis syndrome
- Common?
- Path?
- Ix?
- Prognosis?
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Anorectal malformations: imperforate anus
- What is the role of radiology in these?
- How is this done?
- What is assoc w/a high ARM in males vs. females?
- What other 2 associations?
- What is Tx in either sex for a high lesion?
- Tx for low lesion?
- How to clinically diagnose high vs. low?
- Ix used to diagnose?
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Neonatal low/distal bowel obstruction: meconium ileus
- Path?
- Complication?
- Ix Fx-2.
- What is meconium ileus the earliest manifestation of?
- What is the relationship here?
- Classic Ix findings-2
- Tx-2
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Peds GI ED: malrotation/midgut volvulus:
- Path; what actually causes the volvulus?
- Typical presentation.
- How to rule it out?
- Can you have malrotation w/o volvulus?
- What % of infants present in 1st month? % that are symptomatic w/in 1 year?
- The 2 most important anatomy to show on every UGIS?
- Location of a normal duodenojejunal junction?
- Classic XR finding of midgut volvulus?
- Classic UGI finding?
- Ix clues to the presence of malrotation-5
- Tx?
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Pediatric lymphoproliferative disorder:
- How are kids different than adults?
- What % of peds xplant pts develop this?
- Which xplanted organs are less at risk of this?
- They’re 2-3x at greater risk.
- 15%
- Renal.

Neonatal low/distal bowel obstruction: Hirschsprung disease
- Path; what does this cause?
- Specific path?
- How often is the entire colon affected?
- 1/3 of kids develop what?
- 5% of kids w/this have what?
- Typical Ix Fx.
- How does this compare to functional immaturity of the colon, i.e., meconium plug?
- Gold standard Dx?
- Tx?
- Aganglionosis of the distal bowel that starts at the anus, causing pinching/lack of bowel relaxation.
- The vagal neural crest cells don’t migrate fully to the bum.
- Rarely, 1-3% is the whole colon affected.
- 1/3 develop enterocolitis similar to NEC.
- T21.
- Rectum will be smaller than dilated sigmoid (usually is the other way around).
- Hirsch is tapered rather than abrupt.
- Bx.
- Tx=surgical.
Fetal GI: esophageal atresia
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- What is the first DDx for pt w/pancolitis, who recently was on abx?
- Ix findings?
- What can this progress to & mortality?
- Pseudomembranous colitis.
- Marked, diffuse wall thickening w/paucity of adjacent fat inflammation.
- toxic megacolon in 5% of cases w/35% mortality.

Solid liver/biliary masses: HCC
- Similar to adults, when is this seen in kids?
- Causes of the above-5
- Tumour markers?
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Neonatal bowel obstruction: duodenal atresia, stenosis, web:
- Classic Ix sign for atresia.
- Classic Ix sign for web.
- Duodenal anomalies have associated abnormalities in what % of cases?
- Most common abnormality?
- What % of babies w/duodenal atresia have Down?
- Name 3 other associated abnormalities.
- DDx double bubble + distal bowel gas.
- double bubble
- windsock deformity
- 50%
- T21
- 30% of atresias have T21
- VACTERL, malrotation, annular pancreas (in 20% of babies w/atresia)
- DDx:
- Annular pancreas
- duodenal web
- malrotation

Fetal GI: distal bowel obstruction
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Fetal GI: general
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Childhood bowel obstruction: DDx
- DDx of the most common causes:
- DDx: AAIIMM
Solid liver/biliary masses: liver mets
- 2 most common liver mets in kids?
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Hepatobiliary neoplasia/masses: cystic: mesenchymal hamartoma
- Benign/malignant?
- Path?
- Tumour markers?
- Ix-2
- Tx?
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Childhood bowel obstruction: Crohn disease
- What % of newly diagnosed Crohn’s pts are kids?
- 30%
Neonatal cholestatic jaundice: approach
- Diff b/w unconjugated & conjugated hyperbili?
- Which one is always abnormal in the neonate?
- Generally, what causes this?
- DDx conjugated, the big ones.
- Goal of imaging in conjugated hyperbili?
- Test of choice?
- What is done to prep for this test?
- How does the test work?
- .
- .
- DDx: biliary atresia (25%), Alagille syndrome, alpha-1-antitrypsin deficiency.

Normal midgut rotation:
- How many degrees, in what rotation?
- Around what structure?
- At what GA does this occur?
- At what fetal age does the physiologic bowel herniation disappear?
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Fetal GI: meconium manifestations
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Hepatobiliary neoplasia/masses: cystic: GB hydrops
- Ix?
- Association?
- Pathologically distended GB w/no signs of infection.
- Kawasaki disease.

Solid liver/biliary masses: hepatoblastoma
- Malignant?
- Notoriety?
- Commonality relative to Wilms & neuroblastoma?
- Age group relative to infantile hemangioma?
- 3 associated syndromes?
- Tumour marker?
- Classic Ix finding
- Other Ix findings-4
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Peds miscellaneous GI: meconium spectrum
- Name the 5 meconium entities & what each causes.
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Peds GI ED: hypertrophic pyloric stenosis
- Path
- Ex-2, age
- Ix:
- XR sign
- US: Dx criteria-2
- DDx-1; how to differentiate
- Tx-2
- .
- .
- Age = 2-8wks.

Solid liver/biliary masses: infantile hemangioma/hemangioendothelioma:
- What do they commonly cause (25%)?
- Tumour markers?
- Which syndrome are these associated w/?
- Ix app
- What particular vascular Ix finding here?
- Clinical course?
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Peds miscellaneous GI: abdo calcs
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Solid liver/biliary masses: undifferentiated embryonal sarcoma (malignant mesenchymoma)
- Kid age?
- Tumour marker?
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Fetal GI: omphalocele
- Midline or off midline?
- Covering or no covering?
- Diff b/w a small or giant?
- Which one has more associated anomalies–omph or gastrischis?
- Midline! (Think, oomph! You get punched in the midline when someone punches you.)
- Covering.
- Small <5cm & more likely to contain only bowel; giant >5cm, are more likely to contain other viscera.
- Omphalocele! Especially T13 & T18.

Neonatal bowel obstruction: overview
- Time for presentation.
- Diff b/w neonates & adults re: bowel & XR.
- Goal of Ix in neonatal obstruction.
- Neonate bowel XR approach:
- Defns of both.
- Tx for proximal obstruction.
- Ix for suspected prox obstruction.
- What does this rule out?
- Primary purpose for an UGI & Tx.
- Ix for suspected distal obstruction?
- What contrast is used for this?
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Childhood bowel obstruction: inguinal hernia
- Path of indirect hernia.
- Where does direct vs. indirect hernia go.
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Peds congenital GE: tracheoesophageal fistula:
- 50% of pts w/TEF have what?
- Again, what does the acronym stand for?
- Name the 3 most common types.
- What is the most common of these 3? Appearance on babygram?
- Next most common & appearance?
- Next most common?
- What morphology does the H-type have?
- .
- .
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- H-type: a continuous esophagus w/o atresia (so a catheter will pass), and with upper esophageal TEF. Presents later in childhood w/recurrent aspiration.

Solid liver/biliary masses: classification
- Draw the flowchart of high vs. low flow peds vascular malformations/neoplasms.
- Which high-flow vascular neoplasm can metastasize?
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Peds congenital GE: gastric atresia
- Sx?
- How does the Sx differ from HPS (hypertrophic pyloric stenosis)?
- Less severe variant?
- Ix finding?
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Fetal GI: pentalogy of Cantrell
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Neonatal low/distal bowel obstruction: ileal/colonic atresia
- Where does the microcolon occur here?
- Is colonic atresia common?
- How do these differ from meconium ileus?
- What most commonly causes microcolon?
- What does the colon look like if the atresia is in the proximal jejunum?
- .
- .
- .
- Distal small bowel obstruction.
- Microcolon may not be present as succus entericus produced by the distal bowel is sufficient to distend the colon.

Hepatobiliary neoplasia/masses: general
- Which 3 factors can be used to narrow the DDx of a hepatobiliary mass?
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- What is the most common surgically treated cause of vomiting in infants?
- What’s the most common reason to perform abdo surgery in any child?
- Hypertrophic pyloric stenosis.
- Appendicits.

Peds GI ED: intussusception
- Which part is which: intussuscipiens vs. intussusceptum.
- Most common location?
- Sx-3?
- DDx bloody stool & thick-walled bowel on US?
- Primary Ix for Dx?
- Sign name?
- 1st line Tx?
- Rule of 3s re: reduction?
- Contrainds to pneumatic reduction-3.
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Fetal GI: duodenal atresia
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Neonatal cholestatic jaundice: biliary atresia
- Which ducts affected?
- HIDA normal finding?
- HIDA abnormal finding?
- How do you definitively rule out atresia w/HIDA?
- Tx?
- What is done in this Sx?
- Prognosis?
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Fetal GI: hyperechoic small bowel
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- What syndrome is Caroli disease part of?
- Autosomal recessive polycystic kidney disease, so look at the kidneys!

Neonatal low/distal bowel obstruction: Ladd bands:
- Rare/common?
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Neonatal proximal bowel obstruction: jejunal atresia/stenosis:
- Path?
- Classic babygram appearance?
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VACTERL:
- What is this?
Vertebral segmentation anomalies
Anal atresia
Cardiac anomalies
TracheoEsophageal fistula
Renal anomalies
Limb (radial ray) anomalies

Neonatal low/distal bowel obstruction: small left colon/functional immaturity of the colon (FIC)/meconium plug syndrome
- Path?
- When is this diagnosed?
- RFs-3.
- Like meconium ileus, does this cause microcolon?
- Is this associated w/CF, like meconium ileus?
- Ix Fx:
- Where is the abnormality located generally?
- Primary DDx?
- How do they differ?
- Tx?
- Path: immaturity of colon ganglion cells.
- It is the most common Dx in neonates who fail to pass meconium.
- RFs: neonates; born to mums who received Mg for pre-eclampsia; born to mums w/DM.
- No! This is not microcolon.
- NO! Not associated w/CF.
- Ix: distal obstructive pattern.
- Will see a narrowed distal colon extending up to the splenic flexure w/ more proximally dilated bowel.
- DDx: high Hirschsprung disease, and these cannot be differentiated w/o Bx.
- Although Hirsch won’t have a distensible rectum & will not resolve after enema.
- Water-soluble enema; this will generally resolve in 2 days.

Neonatal low/distal bowel obstruction: DDx microcolon
- How to diagnose & approach.
- Why are low osmolar, water-soluble contrast agents used?
- Defn microcolon.
- Path? Where does this normally occur & why?
- 2 most common causes?
- DDx microcolon-4
- Why does jejunal atresia not cause microcolon?
- What is succus entericus?
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Peds GI ED: necrotizing enterocolitis
- Who does it affect-4
- What % of neonates w/NEC are full-term?
- Path?
- IxFx, early-2
- Late-3
- 2 common XR pneumoperitoneum findings?
- Most common bowel parts involved?
- Late-3
- Tx: early?
- Late?
- Most common delayed complication?
- Prognosis?
- What Ix findings are diagnostic of NEC?
- 1-3 wks post-delivery of a preterm infant.
- 10%.
- .
- .
- .
- .
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- pneumatosis + portal venous gas.

Peds congenital GE: esophageal atresia
- What is this?
- Path?
- What is this almost always associated with?
- When should esophageal atresia be considered at fetal US?
- Ix babygram-2?
- Ix: fetal US.
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Peds GI ED: appendicitis
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Fetal GI: gastroschisis
- Associated w/other anomalies?
- Where does the herniation lie relative to the umbilical cord?
- Usually any other organs outside?
- No, omphalocele has other anomalies.
- To the right.
- No, that’s omphalocele.
Neonatal cholestatic jaundice: hepatitis
- Can US tell this apart from biliary atresia?
- HIDA finding-2?
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What’s the most common DDx for a complete microcolon?

DDx: meconium ileus or ileal atresia.
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Peds miscellaneous GI: Meckels
- Of what is this a remnant?
- What is on the spectrum of a Meckel? …and what can this cause, clinically?
- On what side of the mid/distal ileum is a Meckel located?
- What is the most common manifestation in young kids?
- …and under what circumstance?
- What can a Meckel less commonly do?
- What are the 2 top Meckel complications in adults?
- List the rule of 2s.
- How to Dx a Meckel causing rectal bleeding?
- When is the only time this is positive?
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- How to differentiate a GI duplication cyst from a lymphatic malformation when diagnosing an abdominopelvic cystic structure?

- Mesenteric lymphatic malformation may contain thin septations in addition to rim enhancement.