Peds CLIPP Flashcards
Caused by a deficiency of lung surfactant and delayed lung maturation, can occur as late as 37 wk
RDS
What is the most common cause of respiratory distress in premature infants
RDS
Who is at increased risk for RDS
infants of diabetic mothers
Result of delayed clearance of fluid from lungs following birth
transietn tachypnea of the newborn
Caused by a collection of gas in the pleural space with resultant collapse of lung tissue
pneumothorax
Who is at increased risk for pneumothorax
mechanical ventilation or underlying lung disease like RDS; premature infants with RDS
What babies are at risk for hypoglycemia
infats of diabetic mothers due to chronic hyperinsulinemic state
Tachypnea is a nonspecific finding in newborns; possible causes
meconium aspiration, hypoglycemia, hypothermia, VSD, PDA, Coartation of aorta, RSD, TTN, pneumothorax, sepsis, congenital diaphragmatic hernia
Risk factors neonatal sepsis
maternal GBS, prolonged rupture of membranes (>18 hrs), delivery <37 wks, maternal fever or chorioamnionitis
premature and tachypneic
RDS, pneumothorax, sepsis
maternal diabetes and tachypneic
TTN and RDS
kernicterus presentation
abnormalities in tone and reflexes, choreoathetosis, tremor, oculomotor paralysis, sensorineural hearing loss and cognitive impairment
Risk factors for bilirubin toxicity
hemolysis, asphyxia, significant lethargy, temp instability, sepsis, acidosis, albumin
Predisposing factors to hyperbilirubinemia
ABO mismatch, breastfeeding, in utero infection, gestational age, Mediterranean ethnicity, microcephaly, Rh incompatibility, small for gestation age, weight loss > 10%
physiologic jaundice
total bili <15 mg/dL in full term infants who are asymptomtic
causes of physiologic jaundice
increased production (breakdown RBC), hepatocyte protein and UDPGT deficiency, lack of intestinal flora to metabilze bile, high B glucuronidase in meconium, intake
Breast feeding jaundice occurs
first week of life when milk supply is low so low intake
breast milk jaundice
first 4-7 d but may not peak until 10-14 d; can persist up to 12 wks
Crigler Nijjar
AR; causes severe unconjugated hyperbili starting in first few days. Caused by decrease bili clearance caused by deficient or completely absent UDPGT and can lead to kernicterus
Gilbert
less severe common cause of unconjugated hyperbilidecrease enzyme function interferes with glucuronidation and conjugation of bili is slowed
presentation biliary atresia
healthy infant who develops jaundice, dark urine, and acholic (pale) stools btw 3-6 wks
treatment biliary atresia
kasai procedure- anastomosis of the intrahep ducts to a loop of intestine to allow bile to drain directly into the intestine
major risk factors hyperbili (TSB >95th percentile)
jaundice iin first 24 hours, blood group incompatibility, gestational age 35-36 wk, previous siblibling, cephalohematoma or significant bruising, exclusive breaskfed, east asia
CXR for TTN
wet looking lungs, no consolidation and no air bronchograms
CXR RDS
diffuse reticulogranular appearance ground glass appearance and air bronchograms
late preterm infants are at risk for
hypothermia, hypoglycemia, respiratory istres, apnea, hyperbilirubinemia, and feeding difficulty
vitamin D dose for breastfed infants
400 IU
What should you ask about in a newborn visit
pregnancy history (age, gravida, infection, meds, complications) Birth hitory (age, weight, size, prenatal health) Feeding (type, amount, freq) Parent questions
Breastfed babies lose an avg of ___% of their birth weight in the ____
5.8; first few days
How many stools and voids is a 3-5 d; and 5-7 day old expected to make
3-5d: V-3-5 S-3-4
5-7d: V- 4-6 S- 3-6
Lethargy
failure to recognize parents or interact with persons or objects
Listless
no interest in what is happening around herself
Toxic newborn description
appearance of pending physiologic collapse such as may be seen in sepsis, poisoning, acute metabolic crisis or shock. Febrile, pale or cyanotic, with depressed mental awareness or extreme irritablility
Distressed child
working hard to maintain physiologic stability such as grunting, rapid breathing in order to maintain oxygenation and ventilation
What things are administered in the first hours or days of life
- hep b vaccine (first 12 hours)
Vit K (immediately) - Erythromycin eye ointment (gonorrhea prophylaxis)
- Critical Congenital Heart Disease Screen
- Hearing screen
differential for neonate with poor feeding and decreasesd activity
congenital hypothyroidism, shaken baby, downs, congenital adrenal hyperplasia and inborn error of metabolism
polycythemia usually occurs when after birth
first few hours to days
findings congenital hypothermia
feeding problems, decreased actiivty, constipation, prolonged jaundice, skin mottling, umbilical hernia
findings congenital adrenal hyperplasia
decreased feeding and activity, salt losing presents with lethargy, vomiting, and dehydration that can progress to shock
findings inborn error of metabolism
typically newborns appear well for at least the first 1-2 days and then become symptomatic d/t protein load in breast milk; initial signs include somnolence and poor feeding followed by voiting and lethargy
findings of botulism
poor suck and weak cry and usually presents 3-4 months of age
hypoxic ischemic encephalopathy
altered mental status shortly after birth; low apgar and multi system dysfunction early in neonatal course
Polycythemia
hematocrit above normal (>65%); may be found incidentally, or present with altered metnatl status and poor feeding; plethora, acrocyanosis or hyperbili; occurs in first few hours to days of lif
Conditions associated with large fontanels
skeletal disorders (rickets, osteogenesis imperfecta) chromosomal (downs) Hypothyroid malnutrition increased intracranial pressure
conditions associated with small fontanels
microcephaly, craniosynostosis, hyperthyroid, normal variant
sunken fontanels
dehydration
bulging fontanels
meningitis, hydrocephalus, subjural hematoma, and lead poisoning
umbilical hernias will spontaneously close by what age
5 yo
serum ammonia would be elevated in what newborn conditions
inborn errors of metabolism esp ornithine transcarbamylase deficiency
Sepsis
SIRS (temp or leukocyte count plus H, tachypnea or acute need for mechanical vent) plus suspected or proven infection
signs of meningitis in infants
fever, hypothermia, bulging fontanelles, lethargy, irriablility restlessness, paroxysmal crying, poor feeding, vomiting and or diarrhea
kernig’s sign
resistance to extension of the knee
brudzinski sign
flexion of the hip and knee in response to flexion of the neck
CSF for bacterial meningitis
Glucose- low
protein- high
WBC- high
CSF for viral meningitis
Glucose- normal
protein- normal or slightly elevated
WBC- elevated
gram stain- negative