Pedigree shiz Flashcards
1
Q
Define genome
A
total genomic material of cell or organism
2
Q
Define gene
A
DNA sequence encoding functional molecules (mRNAs, tRNAs etc)
3
Q
Define allele
A
variant of a gene
4
Q
Define multiple allelism
A
gene has many alleles in the population
5
Q
Wild allele
A
Most frequent allele of a gene in population
6
Q
Locus
A
position of a gene in chromosome
7
Q
Genotype
A
the alleles that make up genetic constitution
8
Q
Complex (compound) heterozygote
A
person with 2 different mutant alleles
9
Q
Homozygote? Heterozygote?
A
Homo –> person with 2 identical alleles
Heter –> person with 2 different alleles
10
Q
Hemizygote
A
person carries only single copy of gene
11
Q
Phenotype
A
observable expression of genotype
12
Q
Phenotypes: Define:
Dominant? Recessive? Codominant?
A
Dom = expressed even in heterozygote form Rec = expressed only in homozygote form Codominant = both alleles expressed
13
Q
List the types of mendelian or monogenic inheritance
A
- Auto. dom
- auto recess
- X linked dom
- x linked rec
- mitchondrial
- y linked
