pediatrics final 2 Flashcards
What are the B-symptoms in lymphoma?
Fever, night sweats, weight loss.
At what platelet count is there major risk of bleeding?
Below10-20 G/l
What to do in case of neutropenic fever?
Broad spectrum empiric antibiotic therapy after taking blood cultures.
What are the tumor markers of neuroblastoma?
Serum neuron specific enolase,
homovanillic acid in urine, vanillylmandelic acid
What are the serum electrolyte deviation in case of tumor lysis syndrome?
Elevated
potassium, phosphate and uric acid, decreased calcium.
What are the alarming signs of retinoblastoma? What examinations are required?
Strabism, leukocoria, recurrent infections - ophthalmoscopic examination.
What is the most common type of malignancy in childhood?
ALL.
What are the symptoms of increased intracranial pressure?
- Headache
- vomiting in the morning
- nuchal rigidity
- setting-sun sign
- focal neurological signs,
- bradycardia,
- high blood pressure,
- irritability,
- bulging fontanelle.
What are the physical symptoms of anemia?
- Fatigue
- paleness
- tachycardia
- systolic heart murmurs.
Treatment of tumor lysis syndrome?
Intravenous hyperhydration, rasburicase or
allopurinol
How does the total iron binding capacity change in case of anemia and inflammation?
Increased in anemia, decreased in inflammation.
What is the treatment of immune thrombocytopenia (first- and second-line treatment.)?
IVIG, corticosteroid
List the signs of dyspnea!
Use of respiratory accessory muscles, intercostalretraction,
jugular retraction
nasal flaring
paradoxical breathing.
List the signs of dehydration!
- Dry, white tongue
- sunken eyes
- sunken fontanelle,
- cold extremities
- decreased urine output
- poor skin turgor
- increased heart rate,
- low blood pressure
At what age do the fontanelles close at the latest?
Posterior fontanelle: by 3 months,
anterior fontanelle: by 18 months.