Pediatric Patient Flashcards

1
Q

Conditions that can predispose a child to respiratory failure (4)

A
  1. ↓ airway resistance (sm, compressible airway)
  2. Low functional residual capacity
  3. ↑ O2 metabolism → ↑ fatigue
  4. ↓ safe apnea time → precipitous hypoxia
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2
Q

Causes of inspiratory vs expiratory stridor.

A
Inspiratory = obstruction above glottis
Expiratory = intrathoracic obstruction

*** Biphasic stridor = critical/fixed obstruction at any level

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3
Q

Proper positioning of child for imaging of neck/soft tissue?

A

Child’s head should be positioned in extension and film taken during inspiration.

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4
Q

Congenital lesions that may cause upper airway obstruction? (3)

A
  1. Choanal atresia - persistence of the bucconasal membrane in the posterior naris – bilateral causes acute resp distress when pt unable to breathe through nose while feeding. Unilateral presents when patent naris is obstructed by swelling/secretions.
  2. Macroglossia - abnormally lg tongue protrudes posteriorly into hypopharynx → obstruction with increased secretions, URI, etc
  3. Micrognathia - abnormally small mandible displaces normal-sized tongue (pierre-robin and treacher-collins syndroms). Obstruction worsens when supine.
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5
Q

Normal measurements of the retropharyngeal space?

A

Soft tissue width should not be larger than 6-7mm at C2, regardless of age.

At C6, should not exceed 14mm in children <15yo, 22mm in adults.

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6
Q

Retropharyngeal abscess –

Common organisms?
Management?

A

Most commonly polymicrobial. Strep and anaerobes are most commonly isolated. Consider MRSA in severe infections (jugular venous thrombosis or mediastinal extension)

IV abx - Clinda and 3rd gen cephalosporin.

Indications for surgical management: scalloping of the abscess wall, rim enhancement, lesions >2cm

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7
Q

Drooling, muffled hot-potato voice, trismus. Bulging/asymmetry of tonsils, Deviation of uvula (in 50% of pts).

Diagnosis?
Common organisms?
Treatment?

A

Peritonsillar abscess
Typically polymicrobial, predominant species S. pyogenes (GAS), S. aureus (incl MRSA), and respiratory anaerobes.

Abx alone are insufficient requires incision and drainage or needle aspiration.

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8
Q

Where is the carotid artery in relation to the tonsils?

A

Lies 25mm posterolateral to the tonsillar pillar in children >12yo

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9
Q

Preferred test for children <4yo for EBV?

A

EBV IgM Ab is preferred for infective mononucleosis (>90% sens), esp in children <4yo who are less likely to generate heterophile Ab iwith primary EBV infection.

Older children and adults: heterophile Ab in 50% w/in 1st week, 60-90% in weeks 2-3.

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10
Q

Adjunctive tx for infective mononucleosis?

Cautions in pediatric patients?

A

Steroids and racemic epinephrine to ↓ tonsillar edema.

*** Tx with glucocorticoids prior to diagnosis of leukemia → delayed diagnosis, ↑ risk of tumor lysis, complicate risk stratification, ultimately may cause fatal complications.

*** Exercise caution in using steroids in children/adolescents with any signs and symptoms of possible lymphoid malignancy.

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11
Q

Pt presenting with woody induration or brawny cellulitis of sublingual/submandibular/submaxillary spaces. Swelling is bilateral, without associated lymphadenopathy.

Diagnosis?
Treatment?

A

Ludwig’s angina

Tx: broad-spectrim abx with anaerobic coverage, airway support, admission.

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12
Q

Epiglottitis -
Common organisms?

Management?

A

H. influenzae type B - most common even with immunizations.

Others: H.flu (type A/F/non-typeable), strep, s. aureus (incl MRSA).
Pseudomonas and canddia if immunocompromised.

Non-infectious - thermal inury, steam inhalation, caustic ingestions, allergy, foreign body, irritants.

Tx: Younger children → secure airway in controlled setting.
Adolescents: IV abx, often do not require immediate airway management.

Abx: 2nd or 3rd gen cephalosporin.

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13
Q

Epinephrine dosing for anaphylaxis (IM and IV)

A

IM: 1mg/mL solution, 0.01 mg/kg up to 0.5mg/dose is initial management and may be repeated twice.

IV: 0.1mg/mL solution at 10mcg/kg bolus, followed by 0.1-1 mcg/kg/min up to 10mcg/min may be necessary for pts in shock.

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14
Q

Most common causes of chronic stridor in infants? (2)

A
  1. Laryngomalacia - incomplete development of cartilage of larynx, partial obstruction formed during inspiration → partial obstruction. Worse with supine position, neck flexion, ↑ resp effort (crying/URI). Most have complete resolution by 2yo.
  2. Vocal cord paralaysis - bilateral → severe resp and stridor, typically requires intervention for airway protection. Associated with CNS abnormalities (arnold-chiari). Unilateral usually L-sided related to traction on L recurrent laryngeal nerve at birth or compression from mediastinal structures. Unilateral → hoarse, weak cry, feeding difficulties, aspiration.
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15
Q

3-4yo presenting with hoarseness, abnormal cry, inspiratory stridor, progresses to severe respiratory distress.

Evaluation shows multiple lesions in larynx and/or vocal cords.

Diagnosis?

A

Laryngeal papilloma - most common benign laryngeal neoplasm in children, 2nd most common cause of hoarseness. Typically acquired 2/2 exposure to HPV via vertical transmission from infected mother.

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16
Q

Where is the most narrow part of the airway in children <8yo?

A

Subglottic space. Completely surrounded by cricoid ring, predisposing this part of the airway to obstruction.

17
Q

2yo presenting with 1-3d prodrome of mild fever and URI → abrupt onset of hoarse voice, high-pitched inspiratory stridor, cough.

Diagnosis?
Common causes?
Evaluation of severity?
Treatment?

A

Croup (laryngotracheobronchitis) - most common infectious cause of upper airway distress and obstruction in childhood.

Parainfluenza = 50-75% of cases. Others = RSV, Influenza A/B, rhinovirus.

Evaluation of severity: Stridor, retractions, cyanosis, HR, RR.
Mild: int barky cough, stridor with agitation only, mild tachypnea and tachycardia. Well-hydrated with normal mental status.
Moderate: stridor at rest worse with agitation, ↑ work of breathing, retractions, ↑ RR/HR. May be fussy but normal mental status. Hypoxia atypical.

Tx: Glucocorticoids (Dexamethasone or inhaled budesonide). Nebulized epinephrine

18
Q

Child presenting with viral prodrome, fever, barky cough, stridor → acute decompensation, high fever, cyanosis, severe distress, poor response to steroids and aerosolized epinephrine, inspiratory and expiratory stridor.

Diagnosis?
Most common organism?
Treatment?

A

Bacterial tracheitis - severe inflammation of tracheal epithelium and production of thick mucopurulent secretions.

Most common: S. aureus (incl MRSA)

Tx: Broad abx: anti-staph (vanco/clinda) + 3rd gen cephalosporin (cefotaxime/ceftriaxone).
Alternative: anti-staph + amp-sulbactam.
PCN-allergic: vanc/clinda + quinolone (cipro for pseudomonas, levo for s. pneumo)

+/- airway management in OR, endoscopic tracheal debridement

19
Q

Definition of mild asthma exacerbation.

ED Treatment?

A

Normal mental status
Mild tachypnea
Mild exp wheezing
SpO2 >95%

Tx: Short acting β agonist (albuterol) x3 in 1h (neb or MDI with spacer)

PO Corticosteroids (Prednisone 2mg/kg max 60mg OR Dexamethasone 0.6mg/kg max 16mg) only if incomplete response or already taking at home.

20
Q

Definition of moderate asthma exacerbation.
ED treatment?

Disposition?

A
Normal mental status
↑ RR
Wheezing throughout expiration
I:E    1:2
Significant accessory muscle use 
SpO2 92-95%
Peak expiratory flow rate 41-70% of personal best 

Tx: 1h continuous SABA (albuterol) + ipratropium +
PO steroids Prednisone 2mg/kg max 60mg OR Dexamethasone 0.6mg/kg max 16mg)

Dispo: Observe 60-90min after SABA ends, if sustained response, d/c. If minimal/no improvement, admit.

21
Q

Definition of severe asthma exacerbation.

ED treatment?

Dispo?

A

Restless/lethargic
I:E 1:>2
Significant accessory muscle use
SpO2 <92%
Peak expiratory flow rate <40% of personal best
** Older children may be bradypneic due to prolonged expiratory phase
Wheezing may be absent 2/2 decreased aeration

Tx: Continuous SABA + Ipatropium. IV steroids. Magnesium. Consider SQ/IM epinephrine/terbutaline.

22
Q

Infant <12mo presenting in December with nasal congestion → tight cough, difficulty feeding → wheezing.

Diagnosis?
Treatment?

A

Bronchiolitis
Tx: supportive with hydration and supplemental O2

+/- nebulized epinephrine if mod-severe disease to avoid intubation.

No benefit for SABAs, corticosteroids.

Ppx with palivizumab (monoclonal Ab) monthly during high-prevalence months for pts <24mo with chronic lung disease, congenital heart disease, h/o prematurity.

23
Q

Definition of tachypnea in:
<1yo
1-5yo
>5yo

A

< 1yo is >50 breaths/min
1-5yo >40 breaths/min
5+yo >30 breaths/min

*** Tachypnea is most sensitive indicator of pneumonia, and may be only manifestation in young child.

WHO has published guidelines for clinical diagnosis of PNA in developing countries and cites tachypnea and retractions as indicators of lower respiratory disease

24
Q

Bacterial pneumonia in neonate (<4w)

Most frequent pathogens? (3)
Inpatient treatment?

A

Most frequent pathogens: GBS, E.coli, other GNR

Tx: Ampicillin + aminoglycoside OR Ampicillin + cefotaxime. Avoid ceftriaxone ( ↑ risk of hyperbilirubinemia)

25
Q

Bacterial pneumonia in infant (3w-3mo)

Most common pathogens?
Outpatient treatment?
Inpatient treatment?

A

Most common: S. pneumo, H.flu, Chlamydia trachomatis (if afebrile), B. pertussis (if afebrile + prolonged cough)

Outpatient tx: Erythromycin estolate or Azithromycin (for pertussis).

Inpatient tx: Ampicillin + cefotaxime/ceftriaxone, Azithromycin for pertussis.

26
Q

Bacterial pneumonia 3mo-4y.

Most common pathogens?
Outpatient tx?
Inpatient tx?

A

S. pneumo, H. flu, GAS

  • outpatient: amox/augmentin/cefuroxime/cefdinir
  • Inpatient: ampicillin/amp-sulbactam/ceftriaxone/cefotaxime, Clinda-vanc if critically ill or worried for MRSA

Mycoplasma pneumonia
- outpatient and inpatient: Azithromycin or clarithromycin

Bortella pertussis (if afebrile with prolonged cough)
- outpatient/inpatient: Azithromycin
27
Q

Bacterial pneumonia >5yo

Most common pathogens?
Outpatient tx?
Inpatient tx?

A

Mycoplasma pneumoniae, chlamydophila pneumoniae
- Outpatient/inpatient: Azithromycin or clarithromycin

S. pneumo, H.flu

  • Outpatient: amox/augmentin/cefuroxime/cefprozil/cefdinir
  • Inpatient: Ampicillin/amp-sulbactam/ceftriaxone/cefotaxime. Clinda-vanc for crtitically ill, suspect MRSA

B. Pertussis (afebrile and prolonged cough)
- Inpatient/outpatient: Azithromycin