Pediatric Neurology Flashcards
Normal Developmental Age upper range for:
Mimics action of others
18 months
Normal Developmental Age upper range for:
Supports weight on forearms
3 months
Normal Developmental Age upper range for:
Pincer grasp
9 months
Normal Developmental Age upper range for:
Babbles
6 months
Normal Developmental Age upper range for:
Runs
24 months
Normal Developmental Age upper range for:
Feeds self from spoon
18 months
Normal Developmental Age upper range for:
Shows likes and dislikes
6 months
Normal Developmental Age upper range for:
1-2 meaningful words
12 months
Normal Developmental Age upper range for:
Smiles appropriately
3 months
Normal Developmental Age upper range for:
Walks with 1 held hand
12 months
Normal Developmental Age upper range for:
Plays with others
24 months
Normal Developmental Age upper range for:
Pulls to stand
9 months
Normal Developmental Age upper range for:
Coos, laughs
3 months
Normal Developmental Age upper range for:
Comes when called
12 months
Normal Developmental Age upper range for:
Transfers objects
6 months
Normal Developmental Age upper range for:
Walks upstairs with assistance
18 months
Normal Developmental Age upper range for:
Releases an object on command
12 months
Normal Developmental Age upper range for:
Imitates sounds
9 months
Normal Developmental Age upper range for:
Opens hands spontaneously
3 months
Normal Developmental Age upper range for:
2- to 3-word sentences
24 months
Normal Developmental Age upper range for:
Plays pat-a-cake, peek-a-boo
9 months
Normal Developmental Age upper range for:
Builds a tower of 6 blocks
24 months
Normal Developmental Age upper range for:
At least 6 words
18 months
Platelet count that contraindicates lumbar puncture
<20 x10^9/L
Lumbar puncture positioning for neonates
seated position
Vertebral level for Lumbar puncture
Between L4-L5 interspace
or
L5-S1
Volume of CSF allowed to drip from lumbar puncture
10-15 mL
Imaging method of choice for detecting
- Intracranial hemorrhage
- Periventricular leukomalacia
- Hydrocephalus in infants with patent anterior fontanelles
Cranial ultrasonography
Age that may require sedation for brain MRI
< 8 yo
This NTD covers the largest proportion of congenital anomalies in the CNS
Hydrocephalus
When does the neural tube close in utero?
3rd or 4th week
What is VACTERL-H?
Vertebral, Anal, Cardiac, Tracheoesophageal, Renal, and Limb anomalies, plus hydrocephalus
Most common type of hydrocephalus in children
Obstructive or Noncommunicating hydrocephalus
Most prominent sign of hydrocephalus in an infant
accelerated rate of enlargement of the head
Most prominent sign of hydrocephalus in older patients
headache
This percussion sign of the skull seen in hydrocephalus indicates separation of the sutures
Cracked pot sound or Macewen sign
This deformity consists of displacement of the cerebellar tonsils into the cervical canal, although not usually associated with hydrocephalus
Type I Chiari malformation
This deformity consists of displacement of the inferior vermis, pons, and medulla into the cervical canal, and it is characterized by progressive hydrocephalus with myelomeningocele
Type II Chiari malformation
Consists of a cystic expansion of the fourth ventricle in the posterior fossa and midline cerebellar hypoplasia, which results from a developmental failure of the roof of the fourth ventricle during embryogenesis
Dandy-Walker Malformation
Medications that may reduce the rate of CSF production providing a temporary relief in hydrocephalus in cases such as Dandy-Walker Syndrome
acetazolamide and furosemide
Other name for Spina Bifida Occulta
Occult Spinal Dysraphism
The most severe form of dysraphism
Myelomeningocele
Open or Spina bifida aperta
Folic acid supplementation should be initiated before conception and continued until at least how many weeks of gestation?
12 weeks
All women of childbearing age who can become pregnant should take how much folic acid daily?
0.4 mg
Women with child previously affected with NTD shall be started with how much folic acid daily, 1 month prior to planned conception?
4 mg
Large defect of the calvarium, meninges, and scalp associated with a rudimentary brain
Anencephaly
Characteristic of seizure described as increased tone or rigidity usually lasting 2 sec up to several minutes
Tonic
Characteristic of seizure described as rhythmic, fast muscle contractions and slightly longer relaxations
Clonic
Characteristic of seizure described as a shock-like contraction of a muscle of < 50 msec
Myoclonic
Characteristic of seizure described as flaccidity or lack of movement
Atonic
The most common aura experience by children consists of:
Epigastric discomfort or pain and a feeling of fear
Routine _____ should be performed in all cases of a first unprovoked nonfebrile seizure to help predict risk of recurrence
EEG
________ is preferred over CT scan and performing this on a nonemergent basis should be considered in patients with seizures
Brain MRI
This is previously referred to as pseudotumor cerebri
Idiopathic intracranial hypertension
T/F:
Lumbar puncture is contraindicated in critical illnesses and skin infection at the site of puncture
True
This useful tool is done by administering a light bolus of iodinated contrast through a large-bore intravenous catheter then acquiring CT images as contrast passes through the arteries within the cranium
Cranial CT angiography
Non-invasive procedure, well-suited for detecting a variety of abnormalities, including those of the posterior fossa and spinal cord
Brain MRI
Give 4 disorders of structure specification in CNS congenital anomalies
Gray matter structures
Neuronal migration disorders
Disorders of connectivity
Commissure and tract formation
Which of the following is not an etiologic factor for hydrocephalus?
A. Hypothermia
B. Valproic acid intake
C. Low red cell folate levels
D. Maternal obesity or diabetes
A.
It should be hyperthermia
Valproic acid intake
Low red cell folate levels
Maternal obesity or diab
The putative genetic link for VACTERL-H
PTEN
Abnormality of which structures in the brain most often causes non-communicating hydrocephalus in children?
Aqueduct of Sylvius and Fourth Ventricle
Type II Chiari malformation represents an anomaly of the hindbrain, probably owing to a failure of _______ development during embryogenesis
pontine flexure
This is the more accurate diagnostic tool for Spinal Bifida occulta at any age
MRI
This is a fluctuant midline mass of the spinal column that might transilluminate usually in the lower back
Meningocele
How many percent of myelomeningocele is located in the lumbosacral region?
75%