Pearls_12 Flashcards
Associations:
Anti-Smooth Muscle
Auto-immune Hepatitis
Associations:
Anti-U1 -RNP
Mixed Connective Tissue Disorder
Associations:
Anti-Jo1
Polymyositis and Dermatomyositis
Anti-Mitochondrial
Primary Biliary Cirrhosis
Anti- SSA (Anti-Ro) and Anti-SSB (Anti-La)
Sjogren’s Syndrome (associated with congenital heart block in baby - if these are positive in mama and can also be positive in Lupus)
Anti-Centromere
- name dx
- assoc with what type of HTN –> therefore, screen with what cardiographic and diagnose it with what procedure?
CREST (Limited (as opposed to systemic) Scleroderma) -> associated with Pulm HTN so screen with ECHO and diagnose with right heart cath
Anti-Topoisomerase (same as Anti-Scl70)
- Dx?
- assoc with? –> so screen with? Dx with what modality?
Systemic (as opposed to limited) Scleroderma -> assoc with Pulmonary Fibrosis so screen with PFTs and diagnose with high res CT chest
Anti-Histone
- Dx?
- name the drugs that cause it?
Drug Induced Lupus (assoc with Hydralazine, INH, Procainamide, Etanercept, Inflixamab, Minoxadil)
Anti-CCP
Rheumatoid Arthritis (more specific than RF)
Anti-Smith and Anti-dsDNA
- Dx?
- which one is more specific?
- which one is assoc with degree of renal involvment?
Lupus (Smith is more specific and dsDNA is assoc with degree of renal involvement)
C-ANCA (aka Anti-proteinase 3)
Wegners (aka Granulomatosis with Polyangiitis)
P-ANCA (aka Anti-myeloperoxidase)
- name two dx it’s assoc with?
Churg Strauss (aka Eosinophilic Granulomatosis with Polyangiitis) and Microscopic Polyangiitis and Ulcerative Colitis
Auto-immune Hepatitis has what diagnostic marker?
Anti-Smooth Muscle
Name the dx marker for the following:
Mixed Connective Tissue Disorder
Anti-U1-RNP
Name the dx marker for the following:
Polymyositis and dermatomyositis
Anti-Jo1