PD and Dementia Flashcards
1
Q
The spinal csf in Alzheimer’s shows a shift in amounts of Beta-amyloid and tau what are they?
A
Increase in Tau
Decrease in B-amyloid
2
Q
What is the main genetic marker of predisposition to Alzheimer’s? (Krain)
A
Apoe e4 (chromosome 19) E2 shows to be neuroprotective
3
Q
What is necessary for diagnosis of PD?
A
- Bradykinesia w/ either rigidity or tremor
- Goos response to L-dopamine
4
Q
What areas of the brain in Alzheimer’s shows lack of metabolism?
A
Temporal and Parietal
