pcs 2 Flashcards

1
Q

fat soluble vitamins?

A

A D E K

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2
Q

water soluble vitamins?

A

B1,2,3,5,6,7,9,12 and C

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3
Q

sources of vitamin A

A

carrots- contain carotenoids, liver- source of retinol

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4
Q

functions of vit A?

A

retinal- eye cells, retinoic acid- gene regulation

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5
Q

symptom of deficiency of vit A?

A

blindness

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6
Q

function of vit d?

A

controls absorption of calcium in GI tract, which is important for bone health and controls phosphorus absorption

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7
Q

function of vit d?

A

controls absorption of calcium in GI tract, which is important for bone health and controls phosphorus absorption

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8
Q

deficiency of vit D?

A

rickets and osteomalacia (softening of the bone)

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9
Q

how does vitamin d regulate calcium

A

increases calcium absorption in the gut, uses parathyroid hormone and reabsorbas Ca2+ in the kidney, liver,

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10
Q

name of vitamin e

A

tocopherol

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11
Q

sources of vitamin e?

A

nuts + plants oils

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12
Q

sources of vitamin e?

A

nuts + plants oils

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13
Q

functions of vit E?

A

antitoxidant, protects unsaturated fatty acids from oxidation

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14
Q

sources of vitamin K?

A

K1- green leafy veggies
K2- animal foods

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15
Q

what vitamin is antagonised with warfarin?

A

vitamin K

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16
Q

source of b1 (thiamine)

A

wholegrains

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17
Q

deficiency of vitamin b1

A

beriberi disease

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18
Q

alcohol inhibits the absorption of what vitamin?

A

B1

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19
Q

source of b2 (riboflavin)

A

liver and milk

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20
Q

deficiency of vit b2 (riboflavin)?

A

raised homocysteine levels, higher CVD risk

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21
Q

source of b3 (niacin)?

A

liver and nuts

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22
Q

symtpoms o deficiency of vit b3 (niacin)?

A

pellagra, dermatitis, diarrhoea, dementia

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23
Q

source of vit b5 (pantothenic acid)

A

dairy, most foods

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24
Q

source of b6 (pyridoxine)

A

wholegrains

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25
deficiency of vit 6 (pyridoxine)
dermatitis, confusion, raised homocysteine levels
26
source of b7 (biotin)
liver
27
function of biotin (b7)
co-factor for some enzymes, stabilised chromatin
28
function of biotin (b7)
co-factor for some enzymes, stabilised chromatin
29
source of folate b9
green leafy vegetables, liver
30
source of folate b9
green leafy vegetables, liver
31
function of folate b9
co-factor for enzymes in rna and dna synthesis, also used in rbc
32
function of folate b9
co-factor for enzymes in rna and dna synthesis, also used in rbc
33
deficiency of folate b9 symptoms
macrocytic anaemia, raised homocysteine levels, neural tube defects
34
source of cobalamin b12 vit
animal foods
35
function of cobalamin b12 vit
dna and rbc synthesis
36
which b vitamin can be used in high doses to help treat cyanide
vitamin b12- as hydroxocobalamin
37
which fluid helps with iron absorption and how?
orange juice- high in vitamin c which helps keep iron in its reduced form
38
name of vit c
ascorbic acid
39
functions of vit c
antioxidant, collagen synthesis, formation of carnitine, reduces iron
40
deficiency of vit c
scurvy
41
7 minerals
iron, Ca, magnesium, zinc, copper phosphorus iodine
42
source of iron
red meat
43
excess and deficiency of iron
E- haematochromatosis, D- microcytic anaemia
44
excess and deficiency of calcium
def- osteoporosis, cv problems
45
excess of magnesium symptoms
diarrhoea
46
excess zinc symptom
copper deficiency
47
excess copper symptoms
damages liver and kidneys
48
source of zinc
fish and meat
49
function of iodine
thyroid hormone for metabolic rate
50
deficiency of iodine symptoms
goitre- swelling of thyroid gland
51
describe iron absorption
ferritin stores Fe3+, fe3+ gets reduced to Fe2+ by ferrireductase, iron within enterocytes can be stored as ferritin or transferred into the bloodstream via the protein ferroportin
52
active form of vitamin d3 is
1,25-dihydroxyvitamin D3 activation involves liver then kidney
53
fat absorption occurs in the
gI tract
54
relationship between b1 and warfarin
warfarin reduces vitamin k recycling- less clotting occurs- so more bleeding occurs
55
prolonged/heavy alcohol consumption can lead to..
b1 deficiency
56
iron deficiency causes what type of anaemia
microcytic anaemia- smaller volume of red blood cell
57
b12 and b9 defiende both cause
macrocytic anaemia
58
glucose typical concentration is..
4.5mM
59
fatty acids are bound to..
albumin
60
TAGs (triacylgylcerols) are within…
lipoproteins
61
what are the major fuels circulating in plasma
glucose, lactate, amino acids, ketone bodies, fatty acids, TAGs
62
what does the body do when there is excess glucose?
glucose is stored as glycogen or fat cell cannot store large amounts of ATP rising ATP levels limit glucose catabolism
63
what does the body do when there is low glucose
glycogenolysis- breaking down glycogen stores lipolysis- breaking down lipids gluconeogenesis- making glucose