pcs 2 Flashcards

1
Q

fat soluble vitamins?

A

A D E K

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2
Q

water soluble vitamins?

A

B1,2,3,5,6,7,9,12 and C

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3
Q

sources of vitamin A

A

carrots- contain carotenoids, liver- source of retinol

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4
Q

functions of vit A?

A

retinal- eye cells, retinoic acid- gene regulation

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5
Q

symptom of deficiency of vit A?

A

blindness

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6
Q

function of vit d?

A

controls absorption of calcium in GI tract, which is important for bone health and controls phosphorus absorption

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7
Q

function of vit d?

A

controls absorption of calcium in GI tract, which is important for bone health and controls phosphorus absorption

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8
Q

deficiency of vit D?

A

rickets and osteomalacia (softening of the bone)

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9
Q

how does vitamin d regulate calcium

A

increases calcium absorption in the gut, uses parathyroid hormone and reabsorbas Ca2+ in the kidney, liver,

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10
Q

name of vitamin e

A

tocopherol

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11
Q

sources of vitamin e?

A

nuts + plants oils

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12
Q

sources of vitamin e?

A

nuts + plants oils

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13
Q

functions of vit E?

A

antitoxidant, protects unsaturated fatty acids from oxidation

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14
Q

sources of vitamin K?

A

K1- green leafy veggies
K2- animal foods

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15
Q

what vitamin is antagonised with warfarin?

A

vitamin K

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16
Q

source of b1 (thiamine)

A

wholegrains

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17
Q

deficiency of vitamin b1

A

beriberi disease

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18
Q

alcohol inhibits the absorption of what vitamin?

A

B1

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19
Q

source of b2 (riboflavin)

A

liver and milk

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20
Q

deficiency of vit b2 (riboflavin)?

A

raised homocysteine levels, higher CVD risk

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21
Q

source of b3 (niacin)?

A

liver and nuts

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22
Q

symtpoms o deficiency of vit b3 (niacin)?

A

pellagra, dermatitis, diarrhoea, dementia

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23
Q

source of vit b5 (pantothenic acid)

A

dairy, most foods

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24
Q

source of b6 (pyridoxine)

A

wholegrains

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25
Q

deficiency of vit 6 (pyridoxine)

A

dermatitis, confusion, raised homocysteine levels

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26
Q

source of b7 (biotin)

A

liver

27
Q

function of biotin (b7)

A

co-factor for some enzymes, stabilised chromatin

28
Q

function of biotin (b7)

A

co-factor for some enzymes, stabilised chromatin

29
Q

source of folate b9

A

green leafy vegetables, liver

30
Q

source of folate b9

A

green leafy vegetables, liver

31
Q

function of folate b9

A

co-factor for enzymes in rna and dna synthesis, also used in rbc

32
Q

function of folate b9

A

co-factor for enzymes in rna and dna synthesis, also used in rbc

33
Q

deficiency of folate b9 symptoms

A

macrocytic anaemia, raised homocysteine levels, neural tube defects

34
Q

source of cobalamin b12 vit

A

animal foods

35
Q

function of cobalamin b12 vit

A

dna and rbc synthesis

36
Q

which b vitamin can be used in high doses to help treat cyanide

A

vitamin b12- as hydroxocobalamin

37
Q

which fluid helps with iron absorption and how?

A

orange juice- high in vitamin c which helps keep iron in its reduced form

38
Q

name of vit c

A

ascorbic acid

39
Q

functions of vit c

A

antioxidant, collagen synthesis, formation of carnitine, reduces iron

40
Q

deficiency of vit c

A

scurvy

41
Q

7 minerals

A

iron, Ca, magnesium, zinc, copper phosphorus iodine

42
Q

source of iron

A

red meat

43
Q

excess and deficiency of iron

A

E- haematochromatosis, D- microcytic anaemia

44
Q

excess and deficiency of calcium

A

def- osteoporosis, cv problems

45
Q

excess of magnesium symptoms

A

diarrhoea

46
Q

excess zinc symptom

A

copper deficiency

47
Q

excess copper symptoms

A

damages liver and kidneys

48
Q

source of zinc

A

fish and meat

49
Q

function of iodine

A

thyroid hormone for metabolic rate

50
Q

deficiency of iodine symptoms

A

goitre- swelling of thyroid gland

51
Q

describe iron absorption

A

ferritin stores Fe3+, fe3+ gets reduced to Fe2+ by ferrireductase, iron within enterocytes can be stored as ferritin or transferred into the bloodstream via the protein ferroportin

52
Q

active form of vitamin d3 is

A

1,25-dihydroxyvitamin D3
activation involves liver then kidney

53
Q

fat absorption occurs in the

A

gI tract

54
Q

relationship between b1 and warfarin

A

warfarin reduces vitamin k recycling- less clotting occurs- so more bleeding occurs

55
Q

prolonged/heavy alcohol consumption can lead to..

A

b1 deficiency

56
Q

iron deficiency causes what type of anaemia

A

microcytic anaemia- smaller volume of red blood cell

57
Q

b12 and b9 defiende both cause

A

macrocytic anaemia

58
Q

glucose typical concentration is..

A

4.5mM

59
Q

fatty acids are bound to..

A

albumin

60
Q

TAGs (triacylgylcerols) are within…

A

lipoproteins

61
Q

what are the major fuels circulating in plasma

A

glucose, lactate, amino acids, ketone bodies, fatty acids, TAGs

62
Q

what does the body do when there is excess glucose?

A

glucose is stored as glycogen or fat
cell cannot store large amounts of ATP
rising ATP levels limit glucose catabolism

63
Q

what does the body do when there is low glucose

A

glycogenolysis- breaking down glycogen stores
lipolysis- breaking down lipids
gluconeogenesis- making glucose