PCP Pharm Drugs Flashcards
Classifications of acetylsalicylic acid
Antiplatelet, analgesic, anti inflammatory, antipyretic
Actions of ASA
Blocks formation of thromboxane A2, which aggregates platelets and restricts arteries
Produces analgesia, anti inflammatory, antipyretic, by inhibiting production of prostaglandins
Indications of ASA
Acute coronary syndrome
Contraindications of ASA (7)
Hypersensitivity Asthma Ulcers Bleeding disorders Pregnancy Children under 15 Unconscious
ASA dosage
160 mg PO chewed
What may potentiate ASA?
Anticoagulant therapy
Patients with What condition should be closely monitored when taking ASA
Diabetics
ASA isn’t recommended for kids and teens due to Reye’s syndrome. What is that?
Acute edema of brain, hypoglycemia, fatty infiltration, liver dysfunction.
If a patient has taken a daily dose or ASA or are on blood thinners, should ASA still be administered?
Yes, unless the patient has JUST taken it
What is dextrose classified as?
Caloric agent
Dextrose actions? (2)
Increases BGL to normal
Osmotic diuretic
Dextrose indications
Severe hypoglycemia
Head injury with symptomatic hypoglycemia
Stroke with hypoglycemia
Contraindications of dextrose
4
Allergy to corn
Hypersensitivity to dextrose
Intracranial hemorrhage
Hyperglycemia
Dose of dextrose for regular adults
25g D50W SIVP q 5 min prn, titrate to BGL > 4.0 mmol/L or patient improvement
Dose of dextrose in head injury
12.5g D50W SIVP repeat if BGL is <4mmol/L or improvement
Dose of dextrose in stroke
12.5g D50W SIVP repeat if BGL <3mmol/L
How do you avoid tissue necrosis when administering dextrose?
Give 1/2 total vol, check IV patentcy
Wernickes Encephalopathy
Reversible lack of vitamin B. Poor voluntary muscle coordination, eye muscle weakness and confusion
korsakoff’s syndrome
Irreversible version or wernickes
Severe memory loss
Increased intracellular glucose levels in cerebral ischemia and hypoxia result in
Intracellular acidosis due to anaerobic metabolism of glucose, neural death
When administering dextrose, closely monitor
BGL, LOC, vitals
Side effects or dextrose
Pulmonary edema, phlebitis, tissue nercrosis, rebound hyper glycemia
Classification of EPI
Sympathomimetic endogenous catecholamine
Actions of EPI (3)
Alpha 1 agonist -peripheral vasoconstriction,
Beta 1 agonist -positive chronotropic, inotropic and dromotropic, increases automaticity in heart
Beta 2 agonist- bronchodilation
Effect of epi on anaphylaxis
Inhibits histamine release
Contraindications of epi (4)
None in emergent situations
Hypersensitivity
Uncorrected tachdysrhythmias
Shock
Dosage of epi
0.3 mg 1:1000 IM q 5min prn max 0.9 mg
What should be closely monitored when giving epi?
HR, BP, ECH