PCM REVIEW Flashcards
what percentage of US adults smoke?
21%
how many people start smoking by age 18?
80%
how many deaths annually can be attributed to smoking?
1 in 5
what is the leading preventable cause of death in the US?
smoking
if you tell someone to quit at each visit you can raise the quit rate by______________
30%
what are the 5 A’s?
- ask about tobacco use
- advise to quit
- assess willingness to try
- assist in quit attempt
- arrange followup
what are the 5 stages of change?
precontemplative contemplative preparation action maintenance
what percent of people who try to quit on their own are smoking within 30 days?
80%
what percentage of smokers quit successfully annually?
3%
how is cognitive therapy involved in smoking cesation?
helps smokers combat addiction, craving triggers, stress/environmental cues and withdrawal sings
what happens to quit rates when counseling is combined with pharmacotherapy?
quit rates double
how does varenicline work?
partial agonist at the alpha4beta2 nicotinich ACh receptor
which antismoking drug is the most effective alone?
varenicline
what are notable adverse effects of varenicline and buproprion?
psychiatric adverse effects
how does buproprion work?
NE and dopamine re-uptake inhibitor (decreases cravings and withdrawal symptoms while interactin with pathways underlying addiction)
rank the smoking cessation drugs from best to worst>
Varenicline>buproprion>nicotine replacement
what is a notable side effect of clonidine?
rebound htn
how does mecamylamine work?
nicotine antagonist (ganglionic blocker) data shows that mecamylamine + nicotine is better than nicotine alone
how does clonidine work?
blocks cravings, anxiety, restlessness, tension and hunger