Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pentose Phosphate Pathway > Pathway > Flashcards

Pathway Flashcards

1
Q

What is the primary function of the pentose phosphate pathway?

A

The primary function is to generate NADPH and ribose-5-phosphate for nucleotide synthesis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

True or False: The pentose phosphate pathway occurs in the mitochondria.

A

False: It occurs in the cytoplasm.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Fill in the blank: The pentose phosphate pathway is also known as the ______ pathway.

A

phosphogluconate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the two main phases of the pentose phosphate pathway?

A

Oxidative phase and non-oxidative phase.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is produced during the oxidative phase of the pentose phosphate pathway?

A

NADPH and ribulose-5-phosphate.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What enzyme catalyzes the first step of the pentose phosphate pathway?

A

Glucose-6-phosphate dehydrogenase.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

True or False: The pentose phosphate pathway is an anabolic pathway.

A

True.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the role of NADPH in cellular metabolism?

A

NADPH is used as a reducing agent in biosynthetic reactions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Multiple choice: Which of the following is NOT a product of the pentose phosphate pathway? A) NADPH B) ATP C) Ribose-5-phosphate D) CO2

A

B) ATP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is ribose-5-phosphate used for?

A

It is used for the synthesis of nucleotides and nucleic acids.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Fill in the blank: The enzyme ______ catalyzes the conversion of ribulose-5-phosphate to ribose-5-phosphate.

A

ribose-5-phosphate isomerase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What can ribulose-5-phosphate be converted into during the non-oxidative phase?

A

Xylulose-5-phosphate and ribose-5-phosphate.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

True or False: The pentose phosphate pathway is entirely reversible.

A

False: It has irreversible steps.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the significance of the enzyme transaldolase in the pentose phosphate pathway?

A

It transfers a three-carbon unit from a ketose to an aldose.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Multiple choice: Which of the following is a key regulatory enzyme of the pentose phosphate pathway? A) Phosphofructokinase B) Glucose-6-phosphate dehydrogenase C) Citrate synthase D) Lactate dehydrogenase

A

B) Glucose-6-phosphate dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What role does insulin play in the regulation of the pentose phosphate pathway?

A

Insulin stimulates the activity of glucose-6-phosphate dehydrogenase.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Fill in the blank: The pentose phosphate pathway is particularly active in ______ tissues.

A

lipogenic

18
Q

What happens to excess glucose-6-phosphate if the pentose phosphate pathway is saturated?

A

It is diverted into glycolysis or glycogen synthesis.

19
Q

True or False: The pentose phosphate pathway is crucial for red blood cell function.

A

True.

20
Q

What are the two main products of the oxidative phase of the pentose phosphate pathway?

A

NADPH and ribulose-5-phosphate.

21
Q

Multiple choice: In which cellular compartment does the pentose phosphate pathway primarily occur? A) Nucleus B) Mitochondria C) Cytoplasm D) Endoplasmic reticulum

A

C) Cytoplasm

22
Q

What is the function of xylulose-5-phosphate in the non-oxidative phase?

A

It can be converted into ribose-5-phosphate or used to regenerate glucose-6-phosphate.

23
Q

Fill in the blank: The pentose phosphate pathway provides reducing power for ______ synthesis.

A

fatty acid

24
Q

What is the role of the enzyme glucose-6-phosphate dehydrogenase in the pentose phosphate pathway?

A

It catalyzes the first and rate-limiting step of the pathway.

25
Q

True or False: The pentose phosphate pathway can operate independently of glycolysis.

A

True.

26
Q

Multiple choice: Which of the following is an important intermediate in nucleotide synthesis? A) Glyceraldehyde-3-phosphate B) 3-Phosphoglycerate C) Ribose-5-phosphate D) Acetyl-CoA

A

C) Ribose-5-phosphate

27
Q

What type of reaction is catalyzed by transketolase in the non-oxidative phase?

A

It catalyzes the transfer of a two-carbon unit.

28
Q

Fill in the blank: The pentose phosphate pathway is crucial for cells that are rapidly ______.

A

dividing

29
Q

True or False: The pentose phosphate pathway generates ATP.

A

False.

30
Q

What is the impact of oxidative stress on the pentose phosphate pathway?

A

It can increase the demand for NADPH to combat oxidative damage.

31
Q

Multiple choice: Which of the following conditions would likely increase the activity of the pentose phosphate pathway? A) Low glucose levels B) High NADPH levels C) High insulin levels D) Low ribose-5-phosphate levels

A

C) High insulin levels

32
Q

What is a potential consequence of glucose-6-phosphate dehydrogenase deficiency?

A

Increased susceptibility to oxidative stress and hemolytic anemia.

33
Q

Fill in the blank: The pentose phosphate pathway is essential for the regeneration of ______ in cells.

A

glutathione

34
Q

True or False: The pentose phosphate pathway is linked to the metabolism of nucleotides.

A

True.

35
Q

What is the end product of the non-oxidative phase of the pentose phosphate pathway?

A

Fructose-6-phosphate and glyceraldehyde-3-phosphate.

36
Q

Multiple choice: Which condition can lead to increased flux through the pentose phosphate pathway? A) Increased fatty acid synthesis B) Decreased glucose availability C) Increased ATP demand D) Decreased ribose-5-phosphate demand

A

A) Increased fatty acid synthesis

37
Q

Fill in the blank: The pentose phosphate pathway is particularly important in ______ cells.

A

adipose

38
Q

What is the function of NADPH produced in the pentose phosphate pathway?

A

It is used in reductive biosynthetic reactions and antioxidant defense.

39
Q

True or False: The pentose phosphate pathway is involved in the detoxification of reactive oxygen species.

A

True.

40
Q

What is the primary source of ribose-5-phosphate for nucleotide synthesis in the cell?

A

The pentose phosphate pathway.

41
Q

Multiple choice: Which of the following substrates enters the pentose phosphate pathway? A) Fructose B) Galactose C) Glucose D) Lactate

A

C) Glucose

42
Q

Fill in the blank: The pentose phosphate pathway can generate ribose-5-phosphate from ______.

A

glucose-6-phosphate

Pentose Phosphate Pathway (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions