Pathophysiology of eye and care Flashcards
80% of vision loss is causes by 5 conditions
- Age related macular degeneration (AMD)
- Cataract
- Diabetic retinopathy
- Glaucoma
- Under-corrected and uncorrected refractive error
What percentage of vision loss is preventable and treatable?
75%
People with vision impairment are at a greater risk of suffering from secondary conditions (6)
- Falls
- Depression
- Early special accommodation
- Increased risk of hip fracture
- Increased early mortality
- Social isolation
Vitreous body is filled with vitreous fluid (humor) purpose
Allows the eye to keep its shape
Conjunctiva
A thin mucus membrane that covers the eye
Bulbar conjunctiva with sclera beneath
The white of the eye
Limbus
The junction of cornea and sclera
How does the lens work?
Lens projects inverted image on to retina which produces a signal and sends to the brain to invert it back.
2 types of photosensitive cells
Rods (120 million) and cones (6 million)
Rods are sensitive to…
light
Cones are sensitive to…
colours
Purpose of retinal blood vessels
Nutrition and blood supply to the retina.
Where in the fovea?
The centre of the macula
What is in the fovea?
Cones (colours)
What is in the periphery of the retina?
There are more rods and it becomes slightly thinner
Retinal detachment from bleeding in the eye can cause…
blindness
What is retina detachment?
The retina is lifted or pulled from normal position. Usually occurs when small areas of the retina become torn.
What is the macula?
The area next to optic disc that defines fine details at the centre of visual field
What is age-related macular degeneration (AMD)?
A chronic degenerative condition that affects the central vision; not enough blood supply to area.
What part of the eye is affected in age-related macular degeneration (AMD)?
The macular, disappearance of central vision due to deterioration of pigment layer of retina
What causes degeneration of the macular?
Abnormal blood vessels leaking fluid or blood into the macular.
How does age-related macular degeneration affect the vision?
Black/dankness at the centre of vision.
Functional implications of AMD (7)
- Difficulty distinguishing people’s faces
- Difficulty with close work
- Perceiving straight lines as distorted or curved
- Unable to differentiate between the footpath and road
- Difficulty identifying the edge of steps if there is no colour contrast
- Unable to determine traffic light changes
- Difficulty reading, with blurred words and letters running together
What is a cataract?
A cataract is the clouding of the lens inside the eye. With a cataract, light is scattered as it enters the eye, causing blurred vision; gradual deterioration of lens.
What does early cataract do in spectacle prescription?
Myopic shift so see an optometrist to change glasses prescription
What are the 3 types of cataract?
Congenital, senile and secondary
What part of the eye does cataract affect?
The lens
What can increase the risk of cataract? (3)
- Long term use of corticosteroids can increase risk of cataracts
- Exposure to UV light can also increase the risk
- Ageing, smoking and having diabetes can increase the risk of developing cataract.
How does cataract affect the vision?
Foggy images and the changes in colour perception, yellowing.
Functional implications of cataract
- Blurred vision
- Reduced contrast
- Having difficulty judging depth
- Seeing a halo or double vision around lights at night
- Seeing images as if through a veil/smoke
- Being particularly sensitive to glare and light
- Having dulled colour vision.
What is diabetic retinopathy?
It affects the small blood vessels of the retina. Blood vessels begin to leak and bleed inside the eye
What percentage of people with type 2 diabetes will develop retinopathy?
22%
What to things to do with diabetes, can increase the risk of diabetic retinopathy?
Diabetic kidney disease and type 1 diabetes
How does diabetic retinopathy affect the vision?
The appearance of “clouds” moving in the vision which obstruct a person’s sight.
What part of the eye is affected with diabetic retinopathy?
Leaking blood vessels in the retina
Functional implications of diabetic retinopathy
- Difficulty with fine details (e.g. when reading or watching television)
- Fluctuations in vision from hour to hour or day to day
- Blurred, hazy or double vision
- Difficulty seeing at night or in low light
- Being particularly sensitive to glare and light
- Having difficulty focusing
What are the 4 stages of diabetic retinopathy?
Mild non proliferative
Moderate non proliferative
Sever non proliferative
Proliferative
What treatment is needed during the first 3 stages of diabetic retinopathy?
No treatment unless muscular oedema.
What is proliferative in diabetic retinopathy treated?
Surgery, scatter laser treatment to shrink abnormal blood vessels.
What are some of the complications with scatter laser treatment?
Some loss of vison, but saves the rest of sight
Might slightly reduce colour and night vision
How is macular oedema treated?
Focal laser treatment. Stabilises vision and can reduce risk of vision loss by 50%.
What is glaucoma?
It is a disease that affects the optic nerve at the back of the eye.
Increased intraocular pressure due to a malfunction in eyes aqueous humor drainage system - can lead to optic nerve damage.
What reduces progression of glaucoma?
Relieving pressure on the nerve reduces progression of the disease.
What happens with glaucoma over time?
Gradual loss of peripheral vision.
If untreated - eventually complete vision loss.
What can early detection of glaucoma do?
Early detection and treatment can slow the vision loss.
What part of the eye is affected by glaucoma?
Optic nerve at the back of the eye
How does glaucoma affect the vision?
Peripherally vison so dark around the edges
Where does the fluid flow in glaucoma?
Behind the iris, through the pupil, into the aqueous part, then out though trabecular meshwork.
What is closed angled glaucoma?
The iris blocking the trabecular meshwork
What is opened angled glaucoma?
The iris NOT blocking the trabecular meshwork
What type of glaucoma is more common?
Opened angled glaucoma
What is the treatment aim for glaucoma?
Inhibition or decrease in the aqueous formation. And an increase of uveoscleral outflow.
Risk factors for glaucoma
- Extreme refractive error
- Diabetes
- Migraine
- Cataracts
- Previous eye injuries
- Sleep apnoea
- Gender, males higher risk
- Corticosteroids can increase the risk of developing glaucoma
Functional implications of glaucoma
- No functional implications in early stages, silent disease
- Difficulty adjusting to lighting changes (e.g. between indoors and outdoors)
- Occasional blurred vision
- Seeing a halo around lights (angle closure)
- Increased sensitivity to glare and light
- Difficulty identifying the edge of steps or road
- Tripping over or bumping into objects
What is refractive error?
Refractive error is a focusing disorder of the eye.
How can refractive error be corrected?
It is correctable by wearing glasses or contact lenses or refractive laser surgery (selected cases)
4 types of refractive error?
- HYPEROPIA
- MYOPIA
- ASTIGMATISM
- PRESBYOPIA
How does refractive error affect the vision?
Blurred vision
What is hyperopi?
Far, long sightedness
Hyperopia mechanism
- object focuses behind the retina
- able to see only far objects
What is myopia?
Near, short sightedness
Myopia mechanism
- object focuses in front of the retina
- able to see only close objects
What is astigmatism?
Change in the shape of the lens
Astigmatism mechanism
- abnormal shaped cornea (egg shape instead of spherical)
- object is partially clear and other blurred
What is presbyopia?
The lens not functioning properly
Presbyopia mechanism
- Rigidity of the lens (old age)
- unable to focus
Functional implications of refractive error: long-sightedness (hyperopia)
difficulty seeing near objects
Functional implications of refractive error: short-sightedness (myopia)
difficulty seeing things in the distance
Functional implications of refractive error: astigmatism
blurred vision
Functional implications of refractive error: presbyopia (age focus difficulty)
difficulty seeing near objects occurs from 40 and onwards
Hordeolum (stye)
Inflammatory infection of the hair follicle of the eye lid
Chalazion (meibomian cyst)
Collection of fluid or soft mass cyst
Blepharitis
Inflammation of the margins of the eye lids
Entropion
Inversion of eye lid into eye
Ectropion
Outurned eye lids
Conjunctivitis
Pink eye
Conjunctivitis mechanism
Inflammation of the conjunctiva
Conjunctivitis etiology
- Viral / bacterial
2. Irritants (allergies, chemicals, UV light)
Conjunctivitis symptoms and signs
- Redness / swelling / itching
- tearing when exposed to light
- pus if infectious
- “contagious” with contaminated hands, washcloths
4 types of conjunctivitis
Bacterial, viral, chlamydial, allergic
Treatment for bacterial conjunctivitis
Chloramphenicol
Lid hygiene
Treatment for viral conjunctivitis
Lubricants
Steroids if keratitis
Treatment for chlamydial conjunctivitis
GUM clinic
Azithromycin
Erythromycin
Treatment for allergic conjunctivitis
Lid hygiene,
mast cell stabiliser,
antihistamine,
steroid
Ocular inflammation treatment (4)
- Corticosteroids
- Steroid-Antibiotic Combinations
- Non-Steroidal Anti-inflammatory Drugs (NSAIDS)
- Oral Analgesics
Ocular infection treatment (4)
- Topical Antibiotics
- Oral Antibiotics
- Anti-Viral
- Analgesics
What are mydriatics?
Cause pupil dilation
What are mydriatics used for?
Examine fundus (can see more of retina)
Used as pain relief
Example of mydriatic
Mydriacyl (Tropicamide)
Mydriatics onset
15 mins can last for 3-6 hours
What affect does mydriatics have on vision?
Blurs
What are cycloplegics?
Cause mydriasis and cycloplegia
What is mydriasis?
Dilation of the pupil
What is cycloplegia?
Paralysis of the ciliary muscle that controls focusing of the light rays entering the eye by changing the shape of the crystalline lens.
What are miotics?
Causes pupil constriction
What are miotics used for?
Treatment of glaucoma