Pathophysiology Flashcards
1
Q
Pathophysiology of Type 1 Hypersensitivity reactions (2) + Examples (2)
A
- Anaphylactic
- IgE, Mast cells, Histamine mediated
Examples:
3. Anaphylaxis
- Atopy - asthma, hayfever, eczema
2
Q
Pathophysiology of Type 2 Hypersensitivity reactions (2) + Examples (6)
A
- Cell Bound
- IgG and IgM attatch to cells surface antigens
Examples:
3. AI Haemolytic Anaemia
- ITP
- Goodpasture’s
- Pernicious Anaemia
- Acute Haemolytic Transfusion Reacitons
- Rheumatic Fever
3
Q
Pathophysiology of Type 3 Hypersensitivity reactions (2) + Examples (3)
A
- Immune Complex
- Free antigen and Antibody combine and can deposit in bad places
Examples:
3. Serum Sickness
- SLE
- Post Streptococcal Glomerulonephritis
4
Q
Pathophysiology of Type 4 Hypersensitivity reactions (2) + Examples (2)
A
- Delayed Hypersensitivity
- T-Cell Mediated
Examples:
3. TB
- Graft versus host disease
- Allergic Contact Dermatitis
- Scabies
- MS
- GBS
5
Q
Pathophysiology of Type 5 Hypersensitivity reactions (2) + Examples (2)
A
- Abs that bind or attach cell surface receptors
- Stimulating or turning off the receptor function
Examples:
- Graves
- Myasthenia Gravis
6
Q
A