Pathophysiology Flashcards

1
Q

Pathophysiology of Type 1 Hypersensitivity reactions (2) + Examples (2)

A
  1. Anaphylactic
  2. IgE, Mast cells, Histamine mediated

Examples:
3. Anaphylaxis

  1. Atopy - asthma, hayfever, eczema
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2
Q

Pathophysiology of Type 2 Hypersensitivity reactions (2) + Examples (6)

A
  1. Cell Bound
  2. IgG and IgM attatch to cells surface antigens

Examples:
3. AI Haemolytic Anaemia

  1. ITP
  2. Goodpasture’s
  3. Pernicious Anaemia
  4. Acute Haemolytic Transfusion Reacitons
  5. Rheumatic Fever
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3
Q

Pathophysiology of Type 3 Hypersensitivity reactions (2) + Examples (3)

A
  1. Immune Complex
  2. Free antigen and Antibody combine and can deposit in bad places

Examples:
3. Serum Sickness

  1. SLE
  2. Post Streptococcal Glomerulonephritis
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4
Q

Pathophysiology of Type 4 Hypersensitivity reactions (2) + Examples (2)

A
  1. Delayed Hypersensitivity
  2. T-Cell Mediated

Examples:
3. TB

  1. Graft versus host disease
  2. Allergic Contact Dermatitis
  3. Scabies
  4. MS
  5. GBS
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5
Q

Pathophysiology of Type 5 Hypersensitivity reactions (2) + Examples (2)

A
  1. Abs that bind or attach cell surface receptors
  2. Stimulating or turning off the receptor function

Examples:

  1. Graves
  2. Myasthenia Gravis
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6
Q
A
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