Pathophysiology Flashcards
1
Q
Supratentorial source pain location and causative nerves
A
Anterior to ears, trigeminal nerve
2
Q
Infratentorial source pain location and causative nerves
A
Posterior to ears, C1/C2 - GON (C2), LON (C2/3)
3
Q
Pain receptors
A
Mu, Endorphins - opioids work here, can cause hyperalgesia and worsen migraine over time.
Kappa, Enkephalins - no hyperalgesia, helpful for migraine
Delta, Dynorphins
4
Q
Central antinociceptive network
A
Hypothalamus, periaqueductal grey, raphe nuclei, locus ceruleus, limbic system
5
Q
Endogenous analgesia centers
A
Ant cingulate, amygdala, PAG, parabrachial plexus, VM medulla
