Pathology - Thyroid

Question 1

Gross Features of Follicular & Hurthle Cell Adenoma? What differences might distinguisbh hurtle cell adenoma from follicular adenoma?

Answer 1

Encapsulated
Bulging from cut surface
Solitary Painless Cold nodule

Orange Brown

Question 2

Microscopic features of Follicular and hurtle cell adenoma? What differences might distinguisbh hurtle cell adenoma from follicular adenoma?

Answer 2

1. Encapsulated, no capsular or vascular invasion
   2.Uniform follicles, differentiated from normal parenchyma
2. Macrofollicles, Microfollicles
3. Monotonous cells
4. Cystic change or hemorrhage (rarely)

Oncocytic Change (big, pale abundant pink cytoplasm with more mitochondria)

Question 3

Clinical Features of Follicular or Hurtle Cell Adenoma?

Answer 3

Rarely Hyperfunctioning