Pathology of Ageing

Question 1

Over the last 50-60 years, what has been the general trend in fertility rates across the world?

Answer 1

• Decreasing
• Around 5 children per woman in 1950’s
• Around 2.5 children per woman in 2020’s

Question 2

Over the last 50-60 years, what has been the general trend in life expectancy across the world?

Answer 2

• Increasing
• Around 45 in 1950’s
• Around 70 in 2020’s

Question 3

Over the last 50-60 years, what has been the general trend in the population aged 60 or over across the world?

Answer 3

Increased

Question 4

Why are people getting older?

Answer 4

• Increased resources avilable
• Better economic conditions
• Improved screening programs, earlier diagnosis and treatments
• Better outcomes following major events (cardiac, stroke, surgery)

Question 5

What are the different theories of ageing?

Answer 5

1) Stochastic (cumulative damage or random)
2) Programmed (predetermined or changes in gene expression during various stages)
3) Homeostasis failure