Pathology II Final Flashcards
Pedunculated, tumor-like mass that causes intermittent epistaxis in older equines?
Ethmoidal Hematoma
Top 4 ddx for epistaxis in equines?
- Exercise-induced pulmonary hemorrhage
- Ethmoidal hematoma
- Guttural pouch mycoses
- Trauma
Etiology of Infectious Bovine Rhinotracheitis (IBR)?
Bovine Herpes Virus-1
Pathologic lesions seen with IBR?
FORMATION OF DIPHTHERITIC MEMBRANE!! Necrotic/hemorrhagic fibrous rhinitis \+/- hyperemia, hemorrhage of nasal cavity m.m. \+/- exudate of nasal cavity SOMETIMES interstitial pneumonia
Top 2 ddx for a kitten with conjunctivitis and rhinitis?
- Feline Herpes Virus-1 ==> Feline viral rhinotracheitis
- Feline Calici Virus
REMEMBER to look for oral lesions to help differentiate
Most respiratory viruses result in formation of what lung pathology?
Interstitial pneumonia; inflammation of the interstitium of the lungs
Pathology that is characteristic for chronic S. equi infections?
Bastard strangles ==> Chondroids
Or inspissated exudate: Dried up, rounded, hardened
Chronic cases of strangles can lead to more severe clinical signs such as? Why?
Peripheral neuropathies; close association of medial guttural pouch with cranial nerves
Term for guttural pouch inflammation?
Eustachitis!
Top 3 ddx for guttural pouch problems in equines?
- Guttural tympany (foals)
- Strangles (S. equi infection)
- Guttural pouch mycoses
Most severe complication of guttural pouch mycosis? Why?
Death due to fatal epistaxis; close association of medial guttural pouch with internal carotid artery
Why do you see epistaxis with guttural pouch mycosis and not guttural tympany or strangles?
Fungal organisms LOVE blood vessels!
Diagnostic lesion for Campylobacter spp. induced sheep abortions?
Multifocal necrotizing hepatitis
white target lesions seen diffusely
Two main causes of sheep abortion?
Toxoplasma and Chlamydia
You have an aborted calf with cerebellar hypoplasia. What etiology do you immediately suspect?
BVD!
Bovine Viral Disease Virus
When analyzing the placenta of an aborted fetus of a sheep, it is important to look in between the cotyledons for inflammation. Why?
Toxoplasma ==> INFLAMED cotyledons
Chlamydia ==> inflammation BETWEEN cotyledons
Characteristic lesion of a toxoplasma aborted fetal placenta?
Hemorrhagic cotyledons with foci of necrosis
“Strawberry-like”
What is the etiologic agent of Ovine Enzootic Abortion?
Chlamydia
What is the difference between early and late Chlamydophila abortus infection in terms of abortion?
Early infection = abortion that season
Late infection = abortion during NEXT season
Top 4 places to look when trying to determine etiologic agents of an abortion?
Brain, liver, cotyledons and between them
What unique pathology is seen on a late-term aborted fetus infected with Ureaplasma diversum?
Amnionitis!
Inflammation of the amnion
What is the big deal about Brucella spp infection in cattle?
ZOONOTIC!! Present in MANY fluids!
When you wish to take a sample for culture to determine cause of an abortion, where do you get the sample from?
Stomach contents of aborted fetus
What is the classic histologic lesion seen in aborted fetuses with Chlamydophila abortus and what is its sequel?
Vasculitis of placental blood vessels ==> EDEMA
Which organ do you sample in an aborted fetus when looking for either Neospora or Toxoplasma?
Brain
Top infectious cause of abortions in goats?
Coxiella burnetti
(Q fever)
Common causes of non-infectious abortions in goats?
Trauma, stress
In equines, how many causes of abortions can be determined by direct examination of the placenta and/or umbilical cord?
HALF!
For this reason, it is very important
to lay out the ENTIRE placenta!
Top infectious agent to rule out in an equine abortion case?
EHV-1
Equine Herpes Virus