Pathology Boxes Flashcards
Membrane bound organelle that undergoes apoptosis after completing their function?
Lysosomes
Lipofuscin accumulates in the colon following prolonged use anthraquinone-containing laxatives. What is the clinical condition called?
Melanosisn Coli
Extreme accumulation of iron characterized by cirrhosis, DM and skin pigmentation.
Hemochromatosis
What is the most frequent cause of hemochromatosis?
Repeated blood transfusions
Treatment for hemochromatosis?
Phlebotomy, Chelation(Deferoxamine, Deferasirox)
Conditions with psammoma bodies?
Prolqctinoma, Papillary Thyroid Ca, Serous cystadeno Ca of the ovaries, Meningioma, Mesothelioma
Which type of lung cancer causes paraneoplastic hypercalcemia?
SCCa
Paraneoplastic SIADH and Cushing syndrome?
Small Cell Lung Cancer
Biochemical disorder in heme synthesis that presents with skin blisters due to photosensitivity?
Porphyria
Most common variant of porphyria?
Porphyria cutanea tarda due to URO decarboxylase deficiency
Fever, pleuritic chest pain and pericardial effusion post-MI?
Dressler’s syndrome
Most common common complications of peptic ulcer disease?
Bleeding (MC), perforation, obstruction
Which blood vessels would be injured in the perforation of a gastric ulcer and duodenal ulcer respectively?
Left gastric and Gastroduodenal (MC) arteries
Antibiotic regarded as the most common cause of Pseudomembranous colitis?
Clindamycon
DMARD drug that may cause reactivation of patent tuberculosis infection?
Infliximab (a-tnf inhibitor) - do pod before administering
Electrolyte abnormality seen in acute pancreatitis due to saponification?
Hypocalcemia
Drug for cerebral edema? MOA?
Mannitol (osmotic diuretic); increased blood osm (draws H2O from tissues)
Most common cause of native valve endocarditis?
Streptococcus viridans
What is the most common cause of prosthetic valve endocarditis?
Staph epidermidis
Which bacteria is implicated in Marantic endocarditis
Strep bovis (seen in colorectal Ca )
Most common ecg findingnof pulmonary embolism?
Sinus tachycardia
What do you call a DVT that presents as a pale, painful leg with a diminished arterial pulse due to vasospasm?
Phlegmasia alba dolens
What do you call a DVT that presents as a cyanotic, painful leg due to extebsive thrombotic occlusion?
Phlegmasia cerulea dolens
Usually leads to septic embolism in the lung? Most common microbial cause and setting?
Tricuspid valve endocarditis
Staph aureus
Endocarditis in an IV drug user
