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ABOS Part 1 Neel > Pathology > Flashcards

Pathology Flashcards

1
Q

Smooth Muscle Actin (SMA)

A

Leiomyosarcoma

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2
Q

Desmin

A

Rhabdomyosarcoma

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3
Q

MyoD1/myogenin

A

Rhabdomyosarcoma

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4
Q

S-100

A

Neural - Schwannoma, MPNST

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5
Q

CD34/CD31

A

Hemangioma, angiosarcoma

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6
Q

Beta-catenin

A

Membrane marker, Wnt pathway

Fibromatosis

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7
Q

CD99

A

Ewings

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8
Q

Keratin

A

Epitheliod sarcoma, synovial sarcoma, carcinoma, adamantinoma

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9
Q

Epithelial membrane antigen

A

Epitheliod sarcoma, synovial sarcoma

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10
Q

Vimentin

A

Soft tissue sarcoma

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11
Q

CD20, CD45

A

Lymphoma

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12
Q

CD138

A

Myeloma

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13
Q

t(11;22)

A

Ewing sarcoma, EWS-FLI1

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14
Q

t(12;16)

A

Myxoid liposarcoma, TLS-CHOP

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15
Q

t(2;13)

A

Alveolar Rhabdomyosarcoma, PAX3-FKHR

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16
Q

t(12;22)

A

Clear cell sarcoma, EWS-ATF1

17
Q

t(x;18)

A

Synovial sarcoma, SSX1-SYT

18
Q

t(9;22)

A

Myxoid chondrosarcoma, EWS-CHN

19
Q

Li-Fraumeni

A

Osteosarcoma, p53

20
Q

Rothman-Thomson

A

Sun-sensitive rash with telangiectasias, Osteosarcoma, RECQL4

21
Q

MHE

A

Multiple osteochondromas, EXT1, EXT2

22
Q

Ollier disease

A

Enchondromas –> Chondrosarcomas, PTHR1

23
Q

Maffucci Syndrome

A

Enchondromas + angiomas, pancreatic and ovarian malig –> Chondrosarcomas, PTHR1

24
Q

McCune-Albright

A

Polyostotic fibrous dysplasia, precocious puberty, cafe au lait spots, GNAS1

25
Q

Hand-Schullar-Christian disease (< 5 years)

A

Multifocal LCH and exophthalmos, diabetes insipidus, lytic skull lesions

26
Q

Stuart-Treves

A

Chronic lymphedema, angiosarcoma

27
Q

FAP

A

Desmoid tumor

28
Q

Hand-Schuller-Christain disease

A

Multiple lyric skull lesions, diabetes insipidus (thirsty), exopthalmos

ABOS Part 1 Neel (2 decks)

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