Pathology Flashcards
1
Q
What is subclinical hypothyroidism?
A
Where TSH is high but it is still managing to stimulate enough T4 production.
2
Q
Does subclinical hypothyroidism usually progress to overt hypothyroidism?
A
Usually yes
3
Q
Can thyroiditis produce oncocytic change in cells?
A
Yes (sometimes called Hurthle cells)
4
Q
What are histological signs of papillary thyroid cancer?
A
Psammamatous calcification (black substance)
Orphan annie nuclei (nuclei very pale with central clearing)
Nuclear grooves and inclusions
5
Q
Symptoms of EBV infection.
A
Sore throat
Lymphadenopathy
Jaundice
Upper abdo pain
6
Q
Investigations/management for EBV infection and why?
A
FBC - risk of haemolysis and thrombocytopaenia
Penicillin - hypersensitivity to amoxicillin
Rest (risk of splenic rupture)
