Pathology Flashcards
Desquamative gingivitis is frequently associated with: (A) ulcerative squamous cell carcinoma. (B) plaque induced acute gingivitis. (C) lichen planus. (D) herpetiform infections.
(C) lichen planus.
COMSSAT: 2019 Explanation: Source: Marx, R.E. (2003). Conditions of development disturbances. In R.E. Marx & D. Stern (Eds.) Oral and maxillofacial pathology: a rationale for diagnosis and treatment (pp. 159 ,239-241). Carol Stream, IL: Ouintessence.
Ehlers-Danlos syndrome is caused by a defect of which of the following? (A) Keratin (B) Collagen (C) Elastin (D) Laminin
(B) Collagen
COMSSAT: 2019
Explanation:
Source:
(1997). Oral and maxillofacial surgery clinics of north America (pp. 644-646).
Carlson, E.R. (2004). Odontogenic cysts and tumors. In M. Miloro, G.E. Ghali, P.E. Larsen & P.D. White (Eds). Peterson’s principles of oral and maxillofacial surgery, (vol.1), (pp. 575-596). BC Decker.
Erosive lichen planus is best diagnosed by:
(A) brush biopsy.
(B) immunofluorescence of biopsy specimen.
(C) biopsy of active ulcer.
(D) biopsy of non-ulcerated area.
(D) biopsy of non-ulcerated area.
COMSSAT: 2019 Explanation: Source: Marx, R.E. (2003). Conditions of development disturbances. In R.E. Marx & D. Stern (Eds.) Oral and maxillofacial pathology: a rationale for diagnosis and treatment (pp. 159 ,239-241). Carol Stream, IL: Ouintessence.
A 50 year-old patient presents with a one week onset of increasingly painful vesicles of the oral and nasal mucosa. The patient is febrile and cannot tolerate oral intake. Immunohistochemistry
reveals autoantibodies against epithelial intercellular bridge substances. An appropriate initial treatment would be:
(A) intravenous prednisone.
(B) intravenous gamma globulin.
(C) rituximab (Rituxan).
(D) plasmapheresis.
(A) intravenous prednisone.
COMSSAT: 2019
Explanation:
Source:
Ioannides, D., Lasaridou, E. & Rigopoulos, D. (2008). Pemphigus. Journal of European academy of dermatology and venereology, 22(12), (pp. 1478-1496).
Neville, B.W. (2002). Dermatologic Diseases. In B.W. Neville, D.D. Damm, C.M. Allen & J.E. Bouquot Oral and maxillofacial pathology (2nd Ed), (pp. 655-657). Philadelphia, PA: Saunders.
Marx, R.E. (2003). Conditions of development disturbances. In R.E. Marx & D. Stern (Eds.) Oral and maxillofacial pathology: a rationale for diagnosis and treatment (pp. 159 ,239-241). Carol Stream, IL:
Ouintessence.
Which is true regarding the use of a buccal fat pad graft for the closure of an oral-antral fistula?
(A) Graft survival depends upon primary mucosal coverage.
(B) Success is predictable in the presence of chronic sinusitis.
(C) It is a pedicled graft with an axial vascular pattern.
(D) This technique results in loss of vestibular depth.
(C) It is a pedicled graft with an axial vascular pattern.
COMSSAT: 2019
Explanation:
Source:
Braumann, A., Russmueller, G., Poeschl, E. et. al (2009). Closure of oroantral communications with bichat’s buccal fat pad. Journal of oral and maxillofacial surgery, 67, (pp. 1460-1466).
Papadopoulos, H., Samant, S. & Curtis, N. (2007). Management of oral-antral fistulas: state of the art treatment. Selected readings in oral and maxillofacial surgery, 15.5, (1-27).
A 40 year-old African American female presents for evaluation of mixed radiolucent/radiopaque, round, non-corticated lesions involving the apices of the anterior mandibular teeth. The patient is
asymptomatic. All of the mandibular anterior teeth test vital. Which of the following would be the recommended management?
(A) Obtain a CT scan to further evaluate the extent of the lesion
(B) Obtain a tissue biopsy to confirm the diagnosis
(C) No treatment is necessary
(D) Perform curettage of the lesions and send tissue for pathologic diagnosis
(C) No treatment is necessary
COMSSAT: 2019
Explanation:
Source:
(1997). Oral and maxillofacial surgery clinics of north America (pp. 644-646).
Carlson, E.R. (2004). Odontogenic cysts and tumors. In M. Miloro, G.E. Ghali, P.E. Larsen & P.D. White (Eds). Peterson’s principles of oral and maxillofacial surgery, (vol.1), (pp. 575-596). BC Decker.
Which of the following represents the most appropriate surgical management of an adenomatoid odontogenic tumor?
(A) En-bloc resection with delayed reconstruction
(B) A two-stage surgery: decompression followed by enucleation
(C) Enucleation and curettage
(D) En-bloc resection and excision of surrounding involved soft tissue
(C) Enucleation and curettage
COMSSAT: 2019
Explanation:
Source:
Philipsen, J.P., Reichart, P.A. & Zhang, K.H. (1991). Adenomatoid ordontogenic tumor: biologic profile based on 499 cases. Journal of oral pathology medicine, 20, (pp. 149-158).
Information that may guide the decision for elective neck dissection in patients with T1 and T2 oral cavity squamous cell carcinoma includes which of the following?
(A) Degree of differentiation
(B) Margin status at the time of diagnostic biopsy
(C) Length of time that the cancer has been present
(D) Tumor depth of invasion
(D) Tumor depth of invasion
COMSSAT: 2019
Explanation:
Source:
Holmes, J. & Dierks, E. (2004). Oral cancer treatment. Peterson’s principles of oral and maxillofacial surgery, (2nd Ed), (pp. 631-657). BC Decker.
A metastatic tumor of the mandible in a 70 year-old man is most likely to originate in which of the following anatomic sites? (A) Colon (B) Kidney (C) Lung (D) Breast
(C) Lung
COMSSAT: 2019
Explanation:
Source:
Zarbo, R.J. & Carlson, E.R. (2003). Malignancies of the jaws. In J. Regezi, J. Sciubba & R. Jordan (Eds.) Oral pathology, clinical pathologic correlations, (4th Ed.) (pp. 336). St. Louis, MO: Elsevier.
A 32 year-old patient presents with the following radiographic findings on a panorex film. Aspirations yield a creamy thick fluid while the biopsy shows a thin walled cystic structure with
corrugated lining. This is most consistent with:
(A) dentigerous cyst.
(B) odontogenic keratocyst.
(C) ameloblastoma.
(D) myxoma.
(B) odontogenic keratocyst.
COMSSAT: 2019
Explanation:
Source:
Carlson, E.R. (2004). Odontogenic cysts and tumors. In M. Miloro, G.E. Ghali, P.E. Larsen & P.D. White (Eds). Peterson’s principles of oral and maxillofacial surgery, (vol.1), (pp. 575-596). BC Decker.
