Pathology Flashcards
What is a thrombus?
An intravascular blood clot
How does the consistency, colour and adherence of blood clors vary between thrombi and post morterm clots?
Post moterm is gelatinous whereas, thrombus is firm and brittle. Colour of post moterm is pale on top (like chicken fat)and dark red underneath. Thrombi can adhere whereas post moterm cannot. Thrombi have lines of Zahn
What type of clot forms in large blood vessels?
Mural (occlusive forms in small and medium sized)
What type of clot forms in the heart?
Mural thrombus
What types of clots form in fast flowing vessels?
Pale mostly platelets
What type of clots form in slow flowing vessels?
Red thrombi
What do lines of Zahn show?
The thrombus was formed in life
What is an embolism?
Passage of imsopluble mass within the blood stream and impaction at site distar from point of origin
With examples of each, what is Virchows triad?
Hypercoagubility e.g. Factor V leiden, DIC
Statis e.g. bed red, fibrilation
Endothelial injury e.g. inflammation, hypercholesterolemia
What is a paradoxical embolism?
When a venous thromboembolism traverses a cardiac defect to enter the systemic arterial system.
What normally happems to a thrombembolism?
- Embolism breaks off
- Travels to the IVC
- Gets trapped in the smaller pulmonary arteries, unless a cardiac defect is present –> paradoxical embolism
Where do white infarcts happen and how?
Occurs in arterial occlusion of solid organs with end arterial circulation where tissue density limits the seepage of blood e.g. heart, spleen and kidney.
Where do red infarcts occur?
Red is due to accumulation of blood, where there is loose spongy tissue and dual circulation e.g. lungs, small intestine, testis.
Name three organs with white infarcts?
Kidney, heart,spleen
Name three organs with red infarcts?
Small intestine, lung, testes
