Pathology 1 exam study guide Flashcards

1
Q

Know the significance of desmosomes in skin pathology

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2
Q

How do melasma and Vitiligo differ?

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3
Q

What is the fundamental difference between freckles and Lentigo?

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4
Q

What does the word Lentigo mean?

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5
Q

What are the characteristics of congenital birthmarks?

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6
Q

What is meant by the word nevus?

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7
Q

What characteristics indicate that a nevus may be dysplastic?

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8
Q

Which type of melanoma has the best prognosis, which types have the worse?

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9
Q

What is the most common type of melanoma?

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10
Q

In general, how is the malignant potential of melanoma assessed?

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11
Q

What can Acanthosis Nigricans be an indication of?

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12
Q

What is the sign of Leser-Trelat?

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13
Q

What is the basic pathophysiology of psoriasis?

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14
Q

What test is used in the clinic to evaluate for it?

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15
Q

What is the basic pathophysiology of Pemphigus?

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16
Q

What test are used in the clinic to evaluate for it?

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17
Q

What immunoglobulin is involved in the pathogenesis of Dermatitis Herpetiformis, and what disease is the condition thought to be linked to?

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18
Q

What is the difference between Xerosis and Eczema (the two look similar)?

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19
Q

What is the basis of the butterfly rash of cutaneous lupus erythematous?

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20
Q

Is Pityriasis Rosea a dangerous condition?

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21
Q

What is the difference between Erythema Nodosum and Erythema Multiforme?

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22
Q

What is the significance of actinic keratosis?

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23
Q

What layers are involved with the following: BCC, SCC, Melanoma

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24
Q

Week II

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25
Q

Know the pathological definitions

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26
Q

On an H&E stain, what structures turn blue, and which red?

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27
Q

If proteins in the cytoplasm turn red, how can those normal proteins be differentiated from the protein amyloid, which is found in many diseases?

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28
Q

What types of diseases or conditions might amyloidosis be found in? (the last slide of week II)

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29
Q

Know what a southern, northern, western and dot blot are used to test for.

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30
Q

Cellular injury can cause necrosis or apoptosis, know the difference between the two.

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31
Q

What are common causes of cellular injury?

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32
Q

What is the difference between Marasmus and Kwashiorkor?

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33
Q

There will be questions on vitamin deficiency, and which vitamins, should they be lacking, lead to which diseases.

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34
Q

When does cloudy swelling occur?

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35
Q

Where do free radicals come from?

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36
Q

Be able to describe the basic pathway in an injured cell that begins with mitochondrial dysfunction and leads to cellular swelling

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37
Q

What is the most common form of necrosis, and what are the characteristics of the other forms?

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38
Q

How do the treatments of wet and dry gangrene differ?

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39
Q

What types of diseases is Caseous necrosis characteristic of?

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40
Q

How does gene regulation of apoptosis work?

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41
Q

What do caspases do, and why are they important?

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42
Q

What is steatosis, and what are its two main causes in the western world?

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43
Q

What is the pathological significance and appearance of Lipofuscin?

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44
Q

What is hemosiderosis, and why is it seen in venous stasis ulcers of the lower extremity?

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45
Q

What is the difference between dystrophic calcification and metastatic calcification?

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46
Q

Week III

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47
Q

Know the types of changes that may occur from adaptive responses to injury (i.e, metaplasia, neoplasia, etc.)

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48
Q

Hypertrophy can be causes by both physiologic and pathologic processes, know some examples of each

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49
Q

What is the significance of anaplasia, what are the two chief findings of anaplasia?

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50
Q

Know the difference between primary, secondary, and tertiary (delayed closure) intentions

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51
Q

What is the difference between hypoplasia and agenesis?

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52
Q

Know the different basic types of stem cells, and which basic tissue types have labile, stable, and permanent cells

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53
Q

What are the three stages of fracture healing?

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54
Q

What is the difference between a traumatic fracture and a pathologic fracture?

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