Pathologies Flashcards
Accessory Navicular
Extra navicularIncorporated into tibialis posterior tendonPossible pain and tenderness in areaAssociated with pes planus, putting strain on tib post tendon, leading to inflammationAlso possible irritation from side of shoes
Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis AKA Lou Gehrig’s DiseaseOne of most common neuromuscular diseases, etiology unknown, not known to be autoimmuneDegeneration of upper and lower motor neuronsUnable to send messages to muscles which they control, which leads to atrophyNerves themselves degenerate, not myelin related (unlike MS)LOSS of ability to control VOLUNTARY movement Muscle Atrophy, Rapidly progressive weaknessSpasticityDysarthria (difficulty speaking)Dysphagia (difficulty swallowing)Dyspnea (difficulty breathing)Cognitive function generally sparedDoes not affect sensationSteady decline, worsening symptomsFatal
Arthrogryposis
Congenital joint contracturesRare 1 / 11 000 live birthsGenetic/Environmental- intrauterine, decreased movement in wombAbnormal fibrosis of the muscle tissue, causing shorteningUnable to perform passive extension/flexion in affected joints
Autonomic Dysreflexia
Sudden onset of excessively high blood pressureNot treated promptly, may lead to seizures, strokes and deathOften occurs in spinal cord injured individuals with lesions above T6HeadacheFlushed faceSweatingSlow heart rateReaction of autonomic (involuntary) nervous system to overstimulation (triggered by afferent stimuli), BP increases, HR slows and beomes irregular, BP cannot be restored to normal because of spinal cord damageCauses Overfull bladder/bowelUTIPressure soresBroken bonesTight clothing/DEVICES
Avascular Necrosis
Cellular death (necrosis) of BONE components due to interruption of blood supplyWithout blood, bone tissue dies/collapsesIf involves bones of a joint, often leads to destruction of joint articular surfaces
Blounts Disease
Growth disorder of the tibiaCauses lower leg to angle inward AKA tibial bowing / varaCan be rapidly progressiveThought to be due to effects of weight on the growth plateInner part of the tibia just below the knee fails to develop normally, causing angulation of the boneKAFO, or eventually surgery
Bunions/Bunionette
Hallux abducto valgus deformityLateral deviation of the great toeControversial etiologyPoorly fitting shoes, Genetic factorsPressure applied to the side of the big toe, forces it inward toward and sometimes under or over the other toesBump is from swollen bursal sac or osseus anomaly, also part of the first met head tilted outTissue surrounding joint become swollen and tenderFirst met sesamoid bone may also become deviatedOrthotic splintsToe spacers/separatorsOrthotics (accommodative padding/shielding)Surgery
Carpal Tunnel Syndrome (CTS)
Median entrapment neuropathyCauses Paresthesia (tingling), Pain, NumbnessPalmar aspect of Thumb, index, middle, radial half of ring fingerWrist painSometimes through the night (seems to be aggravated when sleeping with flexed wrist)Caused by crowding/irritation/compression of the median nerve within the carpal tunnel, thickening from irritated tendons or generalized swelling and irritation in the area can cause CTSCarpal tunnel made up of carpal bones, 9 flexors tendons, connective tissue
Charcot Joint
AKA neuropathic arthropathy (joint disease)Progressive degeneration of weight bearing jointBony destructionBony resorptionJoint DeformityDecreased peripheral sensation, proprioception, fine motor controlPathological process can result in UlcerationSuperinfectionLoss of functionAmputationDeathUnderlying Mechanisms (2 theories)Neurotrauma- loss of peripheral sensation- leads to progressive microtrauma to the joint- damage goes unnoticed by patient- resultant inflammatory resorption of traumatized bone renders region weak and susceptible to further trauma-poor fine motor control generates unnatural pressure on certain joints-leading to additional microtraumaNeurovascular- neuropathic patients have dysregulated autonomic nervous system- desensitized joints receive significantly greater blood flow- hyperemia leads to osteoclastic Treatmentimmobilization total contact castPneumatic AFOSurgical correctionTakes 6-9 months for edema/erythema to recede
Charcot Marie Tooth (CMT)
Hereditary Motor and Sensory Neuropathy, Demyelinating neuropathyOne of most common inherited neurological disorders affecting approx 1 / 2500 Characterized by Progressive loss of muscle tissueTouch sensationSymptoms usually begin late childhood, early adulthoodInitial symptom is foot dropClaw toe/Pes CavusAtrophy muscle tissue in legsWeakness in hands and forearmsLoss of touch sensationNeuropathic painPossible respiratory/GI problemsMust avoid prolonged periods of immobility as it can accelerate symptoms of CMTMutations cause defects in neuronal proteinsCause Demyelinating neuropathySCHWANN CELLS demyelinated, Myelin sheath may be damaged, may lead to axonal degenerationSchwann/Myelin/Axon damage leads to poor nerve conduction
Chondromalacia Patella (CMP)
Inflammation of underside of the patella and cartilage softeningAKA patellofemoral pain syndromeCondition may result from acute injury to the patella or chronic friction between the patella and groove in the femur through which it passes during knee flexionOveruse, injury, neuromas, malignment, patellar maltracking etc. can cause deterioration and break down of the cartilageCartilage no longer smooth, making movement painful
Club foot - Talipes Equinovarus
Congenital deformity involving one foot or bothInversion of subtalar joint, complete hindfoot inversionAdduction of forefoot at talonavicular joint and calcaneo cubiod joinitEquinus and varus ankleSupination of entire fototPlantarflexedMay appear to be walking on ankles, lateral sides of their feetNo single known cause, usually single isolated birth defect, associated with other birth defects such as spina bifidaSerial casting has shown to be effectiveFollowed by AFO orthosis to hold feet in plantargrade positionDenis Browne Bar, AFO, FOSurgery usually not necessary however 2 are performedTenotomy- release of achilles tendonAnterior tibial tendon transfer- tendon moved from first ray to the first ray to the third ray in order to release inward traction of foot
Compartment Syndrome
An acute (trauma) or chronic (repetitive activity) condition affecting an upper or lower extremityCharacterized by increased pressure within a muscle compartment causing severe painSwelling within compartment contained by fascia causes increased intracompartmental pressureCompression of muscles, nerves and blood vessels within a closed space can lead to muscle, nerve and circulatory system damageIf left untreated, extensive tissue death can occur, amputation may be necessaryCan lead to volksmans contracture
Congenital Diaphragmatic Hernia (CDH)
Congenital malformation of the diaphragmMost common type is Bochdalek hernia (95% of cases) - hole is posterolateral corner of diaphragm, allows passage of abdominal viscera into chest cavityMalformation of diaphragm allows abdominal organs to push into the proper lung formationLife threatening pathology in infantsCauses death due to 2 complicationsPulmonary hypolasia- incomplete development of the lungsPulmonary hypertension - excessively high blood pressure in pulmonary artery/veinAssociated with scoliosis
Depuytren’s Contracture
Fixed flexion contracture of the hand due to palmar fibromatosis (palmar fascia abnormally thick)Inherited proliferative connective tissue disorderPalmar fascia thickens and shortens so that tendons connected to fingers cannot move freelyFingers bent toward the palm, cannot be fully extendedDecreased ability to grip objectsUsually painlessRing and little finger most commonly affected, middle finger in more advanced cases, index and thumb usually sparedContractures progress slowlyTable top test for diagnosis, hand on table, see if fingers touch the table
Dequervain’s Tenosynovitis
Pain inflammation of 2 tendons in the thumb (extensor pollicus brevis, abductor pollicus Longus) Pain, swelling, tenderness over thumb side of the wrist and base of the thumbMotion may be difficult and painful especially when pinching/grasping objectsDifficulty grippingFrom Overuse, Repetitive Hand or wrist movement, or possibly trauma Finkelstein TestMake fist with thumb placed in palmWrist ulnarly deviated
Down’s Syndrome
Genetic disorder caused by presence of all or part of a third copy of chromosome 21Most common chromosome abnormality in humansPhysical growth delaysMuscle hypotoniaExcessive joint laxity, atlanto-axial instabilityExcessive space between large toe and second toe
Lateral Epicondylitis
AKA Tennis elbowPainful condition of elbow caused by OVERUSE (racquet sports or other activity) or traumaNON inflammatory, Degeneration of tendon’s attachment, weakening of anchor site, placing greater stress on areaPoint of soreness/tenderness over lateral epicondylePain from gripping movements of the wrist, especially wrist extensionExtensor muscles/tendons on lateral epicondyle of humerus damaged from overuseTendon usually involved is Extensor Carpi Radialis Brevis (ECRB)
Medial Epicondylitis
AKA golfer’s elbow, pitcher’s elbowOveruse injury (or trauma) affecting flexor-pronator muscles originating on medial epicondyleRepetitive flexing, gripping, swing, can cause microtears in tendonsPain and inflammation of tendons
Femoral Anteversion/Retroversion
Anteversion - Inward twisting of the femurRetroversion- Outward twisting of the femurOften occurs symmetricallyIn toeing gait, look to see if patella turned inwardBow-legged appearanceCaused by position in uterus, genetic?Normal child born with 40 degrees femoral anteversionGradually decreases to 10 to 15 degrees at adolescense
Guilian-Barre
Rare neurological disorder where body’s immune system attacks its own peripheral nervesOften follows viral/bacterial infection3 / 100 000, mostly age 30-50Results in inflammation of the myelin and blockage of nerve conductionMotor, sensory, autonomic nerve failureAcute symptoms can take place over few hours or daysMuscle weakness/paralysisDifficultly breathing/swallowingInability to move eyesShortness of breathSensation may be affectedSeverity of nerve damage range greatly, most experience ascending symmetrical muscle weakness in lower and upper extremityFollowing acute onset of condition, most patients gradually improve and recover, but some are left with life long disabilityOrthoses to aid in weakness (most commonly drop foot), prevent contracture
Haglunds Deformity
Bony Enlargement at the back of the heelAlso swelling and redness at back of heelMost often leads to painful bursitis (inflammation of fluid filled sac between tendon and bone)Soft tissue near the Achilles tendon insertion becomes irritated when bony enlargement rubs against shoes”pump bump”