Pathogens, antigens and allergens Flashcards
Pathogen
An agent that causes disease
Antigen
Any molecule that may trigger an immune response / activate immune system
Non self antigen
A molecule from outside the body that is recognised by the immune system and initiates an immune response. Also known as a foreign antigen
Major histocompatibility complex ( MHC ) proteins
A group of proteins present on the surface of all self - cells that enables the immune system to distinguish it from non - self material. Also known as self antigens
What are self antigens also called
Major histocompatibility complex 1
MHC I
proteins expressed on all nucleated cells of the body. Therefore most cells of the body minus RBC’S
MHC II
proteins are found on specialized cells of the immune system
Autoimmune disease
A disease in which an individuals immune system initiates an immune response against their own cells
Allergen
A non pathogenic antigen that triggers an allergic reaction
Allergic reaction
An over reaction of the immune system to a non pathogenic antigen
How does a virus infect a cell?
First they must link with host cell and inject DNA / RNA
attachment
penetration
biosynthesis of components
reassembly and lysis
Types of antigens
self antigens
non self antigens
allergens
Malfunctions involving self antigens/self-markers
self cells that set off the immune system.
Disease
Any change that impairs the function of an individual in some way.
Infectious Disease
A disease caused by a pathogen.