Pathogens and their empiric therapy Flashcards
Osteomyelitis and septic arthritis: infant - organisms
Staphylococcus aureus
Streptococcus pyogenes
Streptococcus pneumoniae
Streptococcus agalactiae
Gram-negative organisms
Osteomyelitis and septic arthritis: infant - treatment
Penicillinase-resistant penicillin (dicloxacillin, oxacillin or nafcillin) AND aminoglycoside or ceftriaxone
Osteomyelitis and septic arthritis: child <3 - organisms
S aureus
S pneumoniae
S pyogenes
Kingella kingae
Osteomyelitis and septic arthritis: child <3 - treatment
Ceftriaxone
MRSA suspected: clindamycin or vancomycin
Osteomyelitis and septic arthritis: older child
S aureus
tx with: Cefazolin or penicillinase-resistant penicillin (dicloxacillin, oxacillin or nafcillin)
Osteomyelitis and septic arthritis: Child with sickle cell disease
Salmonella, S aureus
tx with ceftriaxone or vanc
Osteomyelitis and septic arthritis: Adult
S aureus
Suspected MRSA
tx with:
Penicillinase-resistant penicillin (dicloxacillin, oxacillin or nafcillin) OR
Vancomycin plus ceftriaxone
Osteomyelitis and septic arthritis: Immunocompromised adult or child
Gram-positive cocci
Gram-negative organisms
Tx with:
Penicillinase-resistant penicillin AND aminoglycoside
Osteomyelitis and septic arthritis: Septic arthritis in sexually active patients
S aureus
Neisseria gonorrhoeae
Ceftriaxone plus azithromycin
Diskitis
S aureus
Penicillinase-resistant penicillin
Lyme disease
Borrelia burgdorferi
Amoxicillin-doxycycline or cefuroxime
Clenched-fist bite wounds
Eikenella corrodens
Staphylococcus species
Streptococcus viridans
Anaerobes
Ampicillin-sulbactam or piperacillin-tazobactam
Foot puncture wounds
S aureus
Pseudomonas aeruginosa
Penicillinase-resistant penicillin and aminoglycoside or piperacillin-tazobactam
Necrotizing fasciitis
Streptococcus group A beta-hemolytic
MRSA
Gram-positive cocci, anaerobes
± gram-negative organisms
Carbapenem or B-lactam inhibitor
Plus vancomycin or daptomycin
Plus clindamycin
