PATHOGENIC MICROORGANISMS AND PARASITIC HELMINTHS Flashcards
refers to microorganisms that live on or within the
human body without causing disease under normal conditions
Microflora
Human body consists of _____________ eukaryotic cells but harbors ____________ microbial cells
- ~10 trillion
- ~100 trillion
Microbial genes (microbiome) are ____ times the number of human genes.
100
Types of Microflora
Resident Microflora
Transient Microflora
Always present in specific body areas like skin, conjunctiva, mouth, nose, throat, large intestine, and genital openings
Resident Microflora
Temporarily present under certain conditions, such as increased nutrients or moisture
Transient Microflora
Roles of Microflora
Symbiotic Relationship
Protection
Immune System Development
Metabolism
Host provides nutrients and support; microbes affect
host cells and functions
Symbiotic Relationship
Compete with pathogens for nutrients and space
Protection
Assist in the development and regulation of immunity.
Immune System Development
Synthesize vitamins, metabolize nutrients, and influence host gene expression
Metabolism
are microorganisms that can cause disease
Pathogens
Pathogenic Mechanisms
Toxins
Invasion
Immune Evasion
Inflammation
Normally harmless but cause disease under specific conditions
Opportunistic Pathogens
Factors Affecting Microflora and Pathogenicity
Antibiotics
Hygiene Hypothesis
Disrupt gut microbiota for years,
potentially leading to immune or metabolic issues
Antibiotics
Excessive cleanliness may reduce microbial diversity, contributing to allergies and autoimmune disorders
Hygiene Hypothesis
Conditions that create opportunities for such organisms include
- Failure of the Host’s Normal Defenses.
- Introduction of the Organisms into Unusual Body Sites.
- Disturbances in the Normal Microflora
parasitic worms that infect humans and animals
Helminths
Helminths belong to the kingdom __________ and are multicellular __________ organisms
- Animalia
- eukaryotic
Types of Helminths
Flatworms
Roundworms
Flukes
Tapeworms
Thorny-headed worms
▪ Flattened, soft-bodied worms.
▪ Lack a circulatory and respiratory system; rely on diffusion
Flatworms
Can cause infection in the intestines
or the body
Roundworms
Generally infects the bile ducts, liver, or blood
Flukes