Pathogenic Mechanisms of Bacteria

Question 1

Gland type that secretes an oily waxy matter to lubricate skin and hair

Answer 1

Sebaceous glands

Question 2

Protein found in mucosal secretions that binds iron with a high affinity thereby outcompeting most bacteria

Answer 2

Lactoferrin

Question 3

Found in blood/tissue
Function is to limit iron availabilty

Answer 3

Transferrin

Question 4

Found in tissue

Functions include phagocytosis and antigen presentation

Answer 4

Macrophage

Question 5

Found in blood/tissue

Functions include phagocytosis, opsonization, bactericidal

Answer 5

Complement

Question 6

Found in blood

Functions include cytokines, immune functions

Answer 6

Monocytes

Question 7

Found in blood/tissue

Functions include phagocytosis, immune function

Answer 7

PMN’s

Question 8

Disease causing microorganism

Answer 8

Pathogen

Question 9

The physiological processes involved in the generation of clinical signs of disease

Answer 9

Pathogenesis

Question 10

Capacity of a microbe to cause disease

Answer 10

Pathogenicity

or

Virulence

Question 11

Ability of a microbe to cause disease efficiently or inefficiently

Answer 11

Virulence

Question 12

Component of a pathogen that contributes to its disease-producing potential

Answer 12

Virulence factor

Question 13

Criteria designed to establish causal relationship between causative microbe and a disease

Answer 13

Koch’s postulates

Question 14

Koch’s postulates

Answer 14

Organism found in human/animals with infectious disease but not healthy ones

Organism must be isolated and grown in pure culture

Organism grown in pure culture must initiate disease when re-inoculated into susceptible animals

Organism must be re-isolated from experimentally infected animals

Question 15

Degree of pathogenicity

Answer 15

Virulence

Question 16

3 routes that bacteria can penetrate the gut epithelial layer

Answer 16

M cells

Adherence of fimbriae/pili to epithelial surface

Dendritic cells

Question 17

Bacterial surface proteins that provoke phagocytic ingestion of the bacteria by host cells are called

Answer 17

Invasins

Question 18

Bacterial cell surface proteins that are important for adherence to host cells

Answer 18

Adhesins

Question 19

Prevents phagocytosis of bacterial cell and resists complement activation

Answer 19

Capsule

Question 20

Helps make iron available to bacteria

Answer 20

Siderophores