Pathies Flashcards

1
Q

Some normocytic and chromic / hemolytic anemia

A

Ss

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2
Q

F

A

Alpha

Gamma

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4
Q

Due to deoxyhgb formation

SS

A

Hgb insolubility

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5
Q

changes of hp

A

Rbc deformability

Electrophoretic mobility

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6
Q

Char by sickle cell

A

Ss

Drepanocyte

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7
Q

Immunity to malaria (p. falciparum)

A

Ss and as

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9
Q

Polychromasia of ss due to

A

High retic

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10
Q

Both globin chain

A

Homo

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12
Q

Washington monument like crystals (red)

A

Cc

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14
Q

Microcytic hypochromic

A

Thalassemia

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15
Q

Primary poikilocytosis

A

Target or codo

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16
Q

Sickle gene and c gene

A

Sc

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17
Q

A2

A

Alpha

Delta

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19
Q

Inclusion bodies in ss

A
Sickle
Target
Howell
Nrbc
Pappenheimer
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20
Q

Less sever than hgb s but more severe than c

A

Sc

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21
Q

No a1 with 90 f

A

Major homo cooleys

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22
Q

Chon of ss

A

High bili

Low haptoglobin

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23
Q

Pos for hgb solubility test

A

As

Sc

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24
Q

Bar of gold crystal

A

Sc crystal

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25
Q

Due to inc response of bm to hemolytic anemia

A

Vaso occlusive crisis

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26
Q

Mild anemia w microcyte and target

A

Homo hgb e

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27
Q

A1 dec

A2 inc

A

Beta minor

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29
Q

Unstable hgb presence of heinz bods and rigid rbc in spleen

A

Hgb h

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30
Q

Dec rate of synthesis of globin

A

Thalassemia

31
Q

No a and b prod

A

Major or severe

32
Q

High bili

A

Mhcool

33
Q

All 4 alpha genes are deleted

A

Major alpha

34
Q

Cannot carry h20

A

Bart’s hgb

Alpha major

36
Q

A1

A

Alpha

Beta

37
Q

Sufficient amt of a and b

A

Minor or mild

40
Q

Major or homozygous aka

A

Cooley’s

41
Q

Prod sufficient amt B-globin chain

A

Minor beta

42
Q

4 beta chain

A

Hgb h

43
Q

No or dec 2 beta

A

Major homo cooleys

44
Q

Excess alpha

A

Major homo cooleys

45
Q

Hp due to

A

Aa sub

46
Q

Inclusion bods in major homo cooleys

A

Heinz

47
Q

Destroyed by spleen and bm

A

Heinz

49
Q

One alpha gene deleted

A

Silent carrier

50
Q

Sign synp of major homo t

A

Hepatospleen
Face bone
Iron overload

52
Q

High rbc ct and target cells

A

Minor alpha

53
Q

Major alpha

A

Hydrops fetalis

54
Q

Rbc in major homo cooleys

A

Target

Tear

55
Q

Dec alpha chain

Excess beta chain

A

Hgb h

56
Q

No normal hgb prod

A

Major alpha

57
Q

Inclusions in major homo cooley

A
Pappen
Nrbc
Basoph stipp
Howel
Heinz
58
Q

6% barts hgb in newborn

A

Minor alpha

59
Q

Increase 5 serum iron

A

Makor hc

60
Q

80% bart’s hgb

A

Alpha major

61
Q

Age symptoms appear in major t

A

6 mon

63
Q

3 alpha genes deleted

A

Hgb h

65
Q

4 gamma

A

BArts hgb

66
Q

Eryth become rigid and trapped in capillaries

A

Ss

68
Q

Kidney failure
Joint swelling
Hyposplenism

A

Ss

69
Q

2 alpha genes deleted

A

Minor alpha

72
Q

One globin

Asymptomatic

A

Hetero

77
Q

Mild anemia

A

Cc

92
Q

Pos for target cell

A

Cc

Sc

95
Q

Tissue necrosis

A

Ss