PATH 375 Gastrointestinal Flashcards
Gastrointestinal fn
absorb nutrients
excrete waste
Gastrointestinal structure
4 layered tube: mucosa (epith, LP, muscularis mucosae), submucosa, muscularis propria, serosa (peritoneum)
blood vessels, lymphatics, nerves (ANS)
MALT
Cleft lip and palate
- def
- factors, severity
congenital anomalies of lip and palate
due to failure of fusion of facial processes
multifactorial disorders, varying severities
Dental caries
- B.
- complications
bacterial erosion of tooth
Strep mutans thrives in sugar with saliva
plaque promotes attachment
complications: pulpitis, apical abcess, periapical granuloma, radicular cyst
Periodontitis
- inflamm of_
- most common cause of_
inflamm of periodontal recesses (gingiva, periodonal memb, alveolar bone)
most common cause of tooth loss
Stomatitis
causes (infectious and noninfectious)
inflamm of mouth (oral mucosa)
infectious causes: virus (herpes), B., fungi (candida)
non-infectious causes: aphthous ulcers, immunologic
Leukoplakia
Erythrplakia
persistent white/red lesion
Malignant oral neoplasm
- arise from_
- risk
- present
- loc
- mets
- Tx
arise from epith in oral cavity
usu squamous cell carcinoma (95%)
risk: tobacco, alcohol
present: leukoplakia
loc: anterior 2/3 tong, lower lip
mets to regional lymph nodes
Tx: surgery and radiation 5yr 45%
Sialedenitis
- causes
Sjorgren
inflamm of salivary gland (usu parotid)
infectious causes: viral (mumps), bacterial (Staph aureus)
autoimmune causes: Sjogren’s syndrome: immune med inflamm of salivary and lacrimal glands
Pleomorphic adenoma
benign, epith and stromal elements
most common salivary gland tumor
req proper excision, may recur
Esophagitis
inflamm of epith lining of esophagus
causes
infectious: viral (Herpes), fungal (Candida)
chemical: GERD
GERD
- due to
- Barrett’s
inflamm due to reflux of gastric contents allowed by relaxed tone of LES
Barrett’s esophagus: metaplastic intestinal type epith in lower esophagus
- incr risk of adenocarcinoma
- req regular evaluations
Hiatus hernia
2 types
displacemt of portion of stomach above diaphragm
- sliding hernia (90%)
- paraesophageal hernia (10%) portion protrudes, outpouching
Achalasia
incr resting tone of LES
no food enters stomach
Esophageal varices
dilation of submucosal veins of distal esophagus
- usu due to portal hypertension 2º to hepatic cirrhosis
- if rupture, significant morbidity and mortality