Path 1 - Quiz #4 Flashcards

1
Q

Blood coagulation

A

The principle mechanism of hemostasis

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2
Q

Blood clot

A

A mesh of protein filaments that traps blood’s formed elements to form a red, gelatinous mass

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3
Q

Fibrin threads

A

Threads that hold the Baltzell together and they seal the wound to prevent losing of blood

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4
Q

What activates clotting factors in the blood?

A

Injury; through extrinsic and intrinsic pathways.

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5
Q

Where are clotting factors produced?

A

Liver

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6
Q

What is required to produce clotting factors?

A

Vitamin K (via gut flora or external sources)

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7
Q

Clotting Factor I

A

Fibrinogen

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8
Q

Clotting Factor II

A

Prothrombin

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9
Q

Clotting Factor V

A

Preaccelerin

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10
Q

Clotting Factor VII

A

Proconvertin

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11
Q

Clotting Factor VIII

A

Antihemophilic factor

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12
Q

Clotting Factor IX

A

Christmas factor

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13
Q

Clotting Factor X

A

Stuart-Prower factor

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14
Q

Clotting Factor XI

A

Plasma thromboplastin antecedent

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15
Q

Clotting Factor XII

A

Hageman factor

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16
Q

Clotting Factor XIII

A

Fibrin-stabilizing factor

17
Q

Extrinsic pathway takes place via…

A

Damage to cells within and outside the blood vessels

18
Q

What is the extrinsic pathway portion of the coagulation cascade?

A

Tissue factor -> Proconvertin (CF7) -> Stuart-Prower Factor (CF10)

19
Q

Intrinsic pathway takes place via…

A

Exposure of collagen fibers of us endothelial cells of blood vessels to blood flow. Thus, activating clotting factors.

20
Q

Hemostasis

A

the process of stopping blood loss

20
Q

What is the intrinsic pathway portion of the coagulation cascade?

A

Collagen fibers exposed -> Hageman factor (CF12) -> Plasma Thromboplastin Antecedent (CF11) -> Christmas factor (CF9) -> Stuart-Prower Factor (CF10)