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Past qs Flashcards

1
Q
  1. Clinical signs caused by Rhodedendron species?
    a. Bradycardia, hypotension
    b. Muscle tremors, recumbency
    c. Neither
    d. Both
A

d.Both

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2
Q
  1. Which substance is found in Rhodedendron species?
    a. Gitagin
    b. Gonyautoxin
    c. Protopine
    d. Grayanatoxin
A

d.Grayanatoxin

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3
Q
  1. Which medicine is useful in the treatment of poisoning by Autumn Crocus?
    a. Both
    b. Emetic agents, gastric lavage
    c. Saline purgatives
    d. Neither
A

a.Both

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4
Q
  1. Which plant is known to cause damage primarily to the Gastro Intestinal tract?
    a. Autumn crocus
    b. Horstetail spp.
    c. Hellebore spp.
    d. Groundsel spp.
A

a.Autumn crocus

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5
Q
  1. During the metabolism of organophosphates the following process causes the increase of toxicity of the substance:
    a. Substitution of fluor to sulphur
    b. Substitution of fluor to oxygen
    c. Substitution of sulphur to oxygen
    d. Substitution of oxygen to sulphur
A

c.Substitution of sulphur to oxygen

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6
Q
  1. Which plant is known to cause damage primarily to the Gastro Intestinal tract?
    a. Solanum spp.
    b. Sudan grass
    c. Lamb’s quarter
    d. Bracken fern
A

a.Solanum spp.

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7
Q
  1. Which is the most toxic part of Colchicum autumnale?
    a. Both
    b. Neither
    c. Bulb
    d. Flower
A

a.Both

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8
Q
  1. Which disease results from poisoning by Solanum dulcamara?
    a. Both
    b. Haemolysis
    c. Atropine-like nervous symptoms
    d. Neither
A

a.Both

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9
Q
  1. Which of the following mechanism of effect is characteristic to iron?
    a. Blocks the enzymes delta-aminolevulinic acid synthetase, coprogenase and haem synthetase
    b. Increase the saturation level of transferrin causes suppression of the immune system
    c. Decreases glutathione concentration by reducing its synthesis and increasing activity of glutathione peroxidase
    d. Causes lipid peroxidation in the membrane of erythrocytes and lysosomes
A

b.Increase the saturation level of transferrin causes suppression of the immune system

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10
Q
  1. Which antidote is useful in anticoagulant rodenticide poisoning?
    a. Calcium disodium EDTA
    b. D-penicillamine
    c. Vitamin B1
    d. Vitamin K1
A

d.Vitamin K1

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11
Q
  1. Which mechanism of action is characteristic to D-penicillamine?
    a. It inhibits the function of NAD-dependent diaphorase I
    b. It blocks copper-containing enzymes
    c. It helps the accumulation of copper in the hepatocytes
    d. It binds the poison
A

d.It binds the poison

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12
Q
  1. Which clinical feature is characteristic to carbon monoxide toxicosis?
    a. Both
    b. Hypoxic state
    c. Coma, convulsions
    d. Neither
A

a.Both

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13
Q
  1. Which compounds cause liquefaction necrosis?
    a. Acids
    b. Alkalis
    c. Both
    d. Neither
A

d.Neither

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14
Q
  1. Which is characteristic to nitrophenols?
    a. They cause contact dermatitis on the skin
    b. Inhibit the enzyme aldehyde dehydrogenase in the liver
    c. Rigor mortis develops fast
    d. Deferoxamine is the antidote
A

c.Rigor mortis develops fast

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15
Q
  1. What are the gross findings in carbon monoxide toxicosis?
    a. Both
    b. Blood has cherry red colour
    c. Small haemorrhages in organs and nervous system
    d. Neither
A

a.Both

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16
Q
  1. What is the recommended dose of Vitamin K1 in bromadiolon poisoning?
    a. 140mg/kg bw
    b. Not used in bromadiolon toxicosis
    c. 10-50mg/kg bw
    d. 3-5mg/kg bw
A

d.3-5mg/kg bw

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17
Q
  1. What mechanism of effect is characteristic to carbon monoxide?
    a. Binds reversibly to haemoglobin, rendering it incapable of oxygen transport
    b. Irritate respiratory epithelium
    c. Inhibits methaemoglobin reductase
    d. Binds irreversibly to haemoglobin
A

a.Binds reversibly to haemoglobin, rendering it incapable of oxygen transport

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18
Q
  1. Which antidote is useful in copper poisoning?
    a. Pralidoxime
    b. Deferoxamine
    c. Dimercapol
    d. D-penicillamine
A

d.D-penicillamine

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19
Q
  1. What is the recommended dose of sodium thiosulphate in cyanide poisoning?
    a. 0.5mg/kg bw
    b. 5-10mg/kg bw
    c. 50-100mg/kg bw
    d. 500-1000mg/kg bw
A

d.500-1000mg/kg bw

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20
Q
  1. Which mechanism of effect is characteristic to carbon dioxide?
    a. Both
    b. Neither
    c. Causes respiratory disturbances, ataxia, and at higher doses convulsions
    d. Displaces oxygen physically from blood
A

a.Both

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21
Q
  1. What is characteristic to thiram?
    a. The elimination of the substance is slower in dogs than other species
    b. Inhibits the incorporation of iodine in the thyroid gland
    c. Causes deformations of the extremities and abnormal movement in poultry
    d. Yellow discolouration of the organs is experienced during dissection
A

c.Causes deformations of the extremities and abnormal movement in poultry

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22
Q
  1. Which medicine is NOT useful in the treatment of ethylene glycol poisoning?
    a. Sodium bicarbonate
    b. Acetylcysteine
    c. Ethanol
    d. Fomepizole
A

b.Acetylcysteine

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23
Q
  1. What is characteristic to bipyridyl derivatives?
    a. Their absorption in the GI tract is limited
    b. They are eliminated from the organism fast, unchanged or in the form of metabolites
    c. Both
    d. Neither
A

c.Both

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24
Q
  1. Which compounds decrease the amount of oxygen in the blood?
    a. Acids
    b. Alkalis
    c. Both
    d. Neither
A

a.Acids

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25
Q
  1. What is a clinical characteristic of acute nitrophenol poisoning?
    a. Increased frequency of breathing and heartbeat
    b. Salivation, vomiting, diarrhoea, abdominal pain
    c. Both
    d. Neither
A

b.Salivation, vomiting, diarrhoea, abdominal pain

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26
Q
  1. Which compounds cause perforation of the GI tract after oral intake?
    a. Acids
    b. Alkalis
    c. Both
    d. Neither
A

c.Both

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27
Q
  1. What is characteristic to diquat?
    a. Rigor mortis develops fast
    b. Deferoxamine can be applied as an antidote
    c. On the skin it causes contact dermatitis with erythema
    d. Inhibits alcohol dehydrogenase in the liver
A

c.On the skin it causes contact dermatitis with erythema

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28
Q
  1. Which compound accumulates in the bones?
    a. Copper
    b. Lead
    c. Selenium
    d. Organochlorides
A

b.Lead

29
Q
  1. Which compound accumulates in the bones?
    a. Lead
    b. Fluoride
    c. Both
    d. Neither
A

c.Both

30
Q
  1. What is the clinical characteristic of acute aflatoxin poisoning?
    a. Both
    b. Neither
    c. Vomiting, bloody-mucous diarrhea
    d. Depression, weakness, dyspnea
A

a.Both

31
Q
  1. What is the clinical characteristic of acute aflatoxin poisoning?
    a. Liver damage
    b. Hyperpnea
    c. Excitement
    d. Coma, tonic-clonic convulsions
A

a.Liver damage

32
Q
  1. To which carbon monoxide binds to in the bloodstream?
    a. To albumin
    b. To haemoglobin
    c. To globulin
    d. To the surface of erythrocytes
A

b.To haemoglobin

33
Q
  1. Which factor increases the toxicity of aflatoxin?
    a. Both
    b. Neither
    c. The adequate level of Vitamin A of the feed, because it modifies the metabolism of aflatoxin
    d. Appropriate levels of antioxidants in feedstuff
A

b.Neither

34
Q
  1. What is characteristic to the kinetic profile of aflatoxin?
    a. Aflatoxin B1 accumulates in high amounts in the liver, kidney, bone marrow and lungs
    b. Aflatoxins accumulate mainly in the brain
    c. Aflatoxins are absorbed primarily from the stomach
    d. Aflatoxins are not metabolised in the body
A

a.Aflatoxin B1 accumulates in high amounts in the liver, kidney, bone marrow and lungs

35
Q
  1. Which statement is true?
    a. Antioxidants decrease the toxicity of aflatoxin
    b. A high protein level of the feed decreases aflatoxin toxicity
    c. Aflatoxins are absorbed primarily from the stomach
    d. Aflatoxins are not metabolised in the body
A

a.Antioxidants decrease the toxicity of aflatoxin

36
Q
  1. In which category does the toxic substance belong if the LD50 is 500mg/kg in rats?
    a. Moderately toxic
    b. Highly toxic
    c. Extremely toxic
    d. Slightly toxic
A

d.Slightly toxic

37
Q
  1. What clinical signs are caused by viperid snakes?
    a. Incoordination
    b. Local painful swelling
    c. Both
    d. Neither
A

c.Both

38
Q
  1. Which mechanism of action is characteristic to nitrite-nitrate?
    a. It inhibits the function of methaemoglobin release
    b. Both
    c. Neither
    d. The methaemoglobin formed is not capable of transporting oxygen
A

d.The methaemoglobin formed is not capable of transporting oxygen

39
Q
  1. Which medicine is useful in the treatment of poisoning caused by viperid snakes?
    a. Analgesics
    b. Neither
    c. Both
    d. Cardiorespiratory stimulants
A

c.Both

40
Q
  1. Which statement is true nitrite-nitrate?
    a. It blocks the function of haemoglobin-synthetase
    b. Both
    c. Neither
    d. It produces nitrosamines in the stomach
A

a.It blocks the function of haemoglobin-synthetase

41
Q
  1. Which mechanism of action is characteristic to nitrate-nitrite?
    a. It induces production of nitrosamines in the stomach
    b. Hydroxylamine produced from them interferes with transaminations
    c. Neither
    d. Both
A

a.It induces production of nitrosamines in the stomach

42
Q
  1. Which medicine is useful in the treatment of poisoning caused by amphibians?
    a. Barbiturate derivative
    b. Atropine
    c. Both
    d. Neither
A

c.Both

43
Q
  1. What mechanism of action is characteristic to toxins in snake venom?
    a. Complement-activating proteins induce an inflammatory pathway
    b. Neither
    c. Both
    d. Thrombin-like enzymes inhibit blood coagulation
A

c.Both

44
Q
  1. Which clinical signs are caused by poisonous lizards?
    a. Bradycardia
    b. Locomotor disturbances
    c. Hypertension
    d. Oedema at site of bite
A

d.Oedema at site of bite

45
Q
  1. What mechanism of action is NOT characteristic of ethylene glycol?
    a. It binds with ionised calcium to form calcium oxalate crystals
    b. It inhibits the function of alcohol dehydrogenase
    c. It passes through the BBB
    d. Its acidic metabolites cause acidosis
A

b.It inhibits the function of alcohol dehydrogenase

46
Q
  1. What pathological alteration is NOT characteristic in ethylene glycol poisoning?
    a. Kidney failure
    b. Liver failure
    c. Calcium oxalate crystals in renal tubules
    d. Greyish line on the cutting surface of kidney
A

b.Liver failure

47
Q
  1. Which compounds cause perforation of GI tract after oral intake?
    a. Acids
    b. Alkalis
    c. Both
    d. Neither
A

c.Both

48
Q
  1. What statement is correct for dithiocarbamates?
    a. They cause alveolar damage to lung
    b. The elimination of the substance is slower in dogs than other species
    c. Inhibit the incorporation of iodine into the thyroid hormone in the thyroid gland
    d. Yellow discolouration of the organs is experienced during dissection
A

c.Inhibit the incorporation of iodine into the thyroid hormone in the thyroid gland

49
Q
  1. Which medicine is useful in the treatment of poisoning by Solanum spp?
    a. Both
    b. Neither
    c. Tannic acid and activated charcoal in a ratio of 1:2
    d. Calcium ions, antihistamines
A

a.Both

50
Q
  1. Which clinical signs are caused by Cycas spp?
    a. Coagulopathy
    b. Icterus, ascites
    c. Both
    d. Neither
A

a.Coagulopathy

51
Q
  1. Which of the following mechanism of effect is characteristic to lead?
    a. Increase in the saturation level of transferrin causes suppression of the immune system
    b. Blocks the enzymes delta-aminolevulinic acid synthetase, coprogenase, and haem synthetase
    c. Causes severe vasodilation
    d. Causes lipid peroxidation in the membrane of erythrocytes and lysosomes
A

b.Blocks the enzymes delta-aminolevulinic acid synthetase, coprogenase, and haem synthetase

52
Q
  1. What are the gross pathological findings in carbon monoxide toxicosis?
    a. Blood has a cherry red colour
    b. Small haemorrhages in organs and nervous system
    c. Both
    d. Neither
A

c.Both

53
Q
  1. When can carbon dioxide be formed? Which statement is true?
    a. Both
    b. Neither
    c. Fermentation of organic materials
    d. In silos, fruit storages
A

a.Both

54
Q
  1. What are the gross pathological findings in carbon monoxide toxicosis?
    a. Mucous membranes have pale pink discolouration
    b. Tubulonephrosis
    c. Ulcers in the oral cavity
    d. Damage of the gastrointestinal tract
A

a.Mucous membranes have pale pink discolouration

55
Q
  1. What is the recommended dose of D-penicillamine in copper poisoning? (notes say 10-20mg for acute; 10-15mg for chronic)
    a. 5-10 mg/kg bw
    b. 50-100mg/kg bw
    c. 0.2-0.5mg/kg bw
    d. 20-50mg/kg bw
A

?

56
Q
  1. Which mechanism of action is characteristic to D-penicillamine?
    a. It inhibits the function of NAD-dependent diaphorase I
    b. It blocks copper-containing enzymes
    c. It helps the accumulation of copper in the hepatocytes
    d. It binds the poison
A

d.It binds the poison

57
Q
  1. When can carbon monoxide be formed? Which statement is true?
    a. Both
    b. Neither
    c. Incomplete combustion of organic compounds
    d. When using a stove with burning coal
A

c.Incomplete combustion of organic compounds

58
Q
  1. Which antidote is useful in sweet clover poisoning?
    a. Calcium disodium EDTA
    b. D-penicillamine
    c. Vitamin-B1
    d. Vitamin-K1
A

d.Vitamin-K1

59
Q
  1. Which clinical signs are caused by Angel’s Trumpet?
    a. Mydriasis
    b. Dry oral mucosa
    c. Neither
    d. Both
A

d.Both

60
Q
  1. Which plant is known to cause damage primarily to the gastrointestinal tract?
    a. Solanum spp.
    b. Sudan grass
    c. Lamb’s quarter
    d. Bracken fern
A

d.Bracken fern

61
Q
  1. Which medicine is useful in the treatment of poisoning by Autumn crocus?
    a. Fluid therapy, atropine
    b. Special antidote
    c. Anticonvulsive agents
    d. Antacids
A

a.Fluid therapy, atropine

62
Q
  1. Which substance is found in Cycas spp. (false sage palm)?
    a. Cycasine
    b. Macromazine
    c. Neither
    d. Both
A

d.Both

63
Q
  1. Which plant is known to cause damage primarily to the gastrointestinal tract?
    a. Hydrangea spp.
    b. Blue star
    c. Buckwheat
    d. Yew spp.
A

a.Hydrangea spp.

64
Q
  1. Which laboratory result is characteristic to poisoning caused by Cycas?
    a. Decreased levels of liver enzymes and bilirubin
    b. Increased protein content of blood
    c. Metabolic acidosis
    d. Prolongation of the prothrombin- and clotting time
A

d.Prolongation of the prothrombin- and clotting time

65
Q
  1. Which disease results from acute poisoning by Solanum spp?
    a. Both
    b. Neither
    c. Gastric form
    d. Nervous system type
A

a.Both

66
Q
  1. What is NOT characteristic to bipyridyl derivatives?
    a. Inhibitors of photosynthesis in plants
    b. Limited absorption from the intestinal tract
    c. Accumulate within the organism
    d. They are excreted from the organism within 48h
A

c.Accumulate within the organism

67
Q
  1. What is characteristic to paraquad?
    a. Deferoxamine is the antidote
    b. Rigor mortis develops fast
    c. On the skin it causes contact dermatitis with erythema
    d. Because it inhibits the re-uptake of Ca2+ into the sarcoplasmic reticulum, the relaxation time is delayed
A

b.Rigor mortis develops fast

68
Q
  1. Which substances can cause tachycardia, hypertension and arrhythmias?
    a. Propofol
    b. Xylazine
    c. Diazepam
    d. Yohimbine
A

b.Xylazine

Toxicology (1 decks)

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