Past Papers Flashcards

1
Q

Name five conditions that can induce a spontaneous Pulfrich effect. For each
condition, explain why the effect occurs. Example for illustrative purposes:
Reduced colour perception in a patient with ARMD – occurs due to the loss of
foveal cone function. 10 marks

A
  • Multiple sclerosis – the optic nerve may be damaged which can cause a delay in signal transmission to the brain. The difference in timing of the signal transmissions from each eye can cause spontaneous Pulfrich effect.
  • Cataract – the opacities in the lens will absorb light which will cause the stimuli reaching the retina in the affected eye to be reduced compared to the fellow eye.
  • Corneal opacity – The light entering the eye will be unequal at the retina due to increased scatter and possible absorption by the corneal opacities causing the signal reaching the retina to be unequal.
  • Anisocoria – The difference in pupil size will mean that the intensity of the stimuli reaching the retina will be unequal.
  • Central serous retinopathy – fluid build-up behind the retina will cause the neural signals in the affected eye to be delayed
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2
Q

Identify and discuss problems and impairments that may be associated with neurological loss which make communication more difficult with this population. 5 marks

A

• Patients may have other neurological conditions such as dementia which can limit their ability to understand the findings of an eye exam
• Patients could have neurological impairment due to traumatic brain injury which can cause memory impairment meaning they are unable to retain the information given to them or limit their ability to understand this information
• If patients have suffered recent vision loss due to neurological problems they may be unable to accept their condition (they may be following the loss model and be in stage 1-4 which can affect their ability to deal with their vision loss) making it more difficult for the practitioner to communicate with these patients
- inability to read
- patients may be unable to speak however they can still understand and retain information

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3
Q

ii. Describe 5 adjustments/modifications you could make to your assessment routine to help achieve better communication. (5 marks)

A

• If the patient has a carer then ensure they are present during the examination.
• While it is important to ensure you are speaking to the patient, the carer may be able to provide important information that the patient cannot
• Keep language simple and speak slowly, ensure that the carer (if present) understands the information being given and invite any questions they may have
• Ensure the priorities are known for this patient
• They may be unable to read so assessing critical reading speed would be unnecessary however, the patient may enjoy other near tasks like drawing which would require an assessment of their best corrected near vision
• It may be appropriate to provide information in writing for these patients, if the patient is able to comprehend this then ensure print size is adequate for their viewing, if not then offer this written information to the carer
• When performing tasks such as subjective refraction it is important to ensure the patient understands the task
- might be easiest to do tests which don’t require the px to speak as much such as retinoscopy

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4
Q

Features of congenital vs aquired CVD 6 marks

A

Type and severity
- aquired CVD may change in severity over time
- congenital is stable

Other visual functions
- aquired may present with other visual abnormalities
- congenital normal

Type
- congenital usually protean/duetan
- aquired Tritan

Male/female
- congenital usually male
- aquired even between both

Diagnosis
- aquired more difficult to classify and gives mixed responses
- congenital easy to diagnose

Same in both eyes
- congenital identical between eyes
- aquired asymmetry

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5
Q

Disadvantages of croma gen lenses 5 marks

A

Disadvantages and problems associated with the use of CromaGen contact lenses for
‘treatment’ of CVD are:
Cosmetically poor; monocular filter or 2 different filters placed in front of each eye They do not provide normal colour perception
They dim retinal illumination which can lead to the pulfrich effect
They can impede binocular fusion and stereopsis
They are not always permitted in certain jobs
The contact lenses are hydrogels to accommodate the tint which increases the chances of the lens drying out along with the associated problems such as dry eye, and hypoxia

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6
Q

ii) Briefly, explain why a CromaGen™ contact lens may enable a colour deficient patient to see an isochromatic plate

A

They reduce transmission of certain wavelengths of light
This in turn introduces a perceived brightness difference between wavelengths of light which did not exist before

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7
Q

I) Define the term “minimum angle of detection (MAD)”.
ii) How would you design an experimental stimulus to measure the MAD? (5 marks)

A

MAD is forced choice of being able to detect the presence of a stimulus, but with no discrimination eg being able to detect a black and white grating against a grey background, the minimum angle subtended can be recognised is the MAD
MAD is the visual angle subtended by the smallest detectable letter on the test chart. It can be measured using a detection acuity chart.

ii
A standard test for MAD would consist of striped patterns matched with uniformly grey targets of the same mean luminance. The px is asked ‘are the stripes on the R or L’ which is v similar to preferential looking tests.
Assumption is that if px can answer correctly, then the visual system must be able to detect the spatial contrast present in the pattern. The stripes get finer towards the bottom of the chart, and the with of the finest bars that can be distinguished is a measurement of detection acuity

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8
Q

i) Define the term “minimum angle of resolution (MAR)”.
ii) How would you design an experimental stimulus to measure the MAR? (5 marks)

A

The MAR is the smallest visual angle that a stimulus can subtend, and still be resolved by the observer. It is typically measured using a high contrast detailed stimulus (eg. A small letter on a letter chart). The observer is required to recognise a feature of the stimulus (eg. Orientation or letter identification)

ii
This could be done through. The use of a resolution chart where the horizontal and vertical stripes are presented in gratings (Thibos & Bradley, 1993). The patient is asked to report whether the horizontal stripes are on the left or right (the stripes on either side are of the same spatial frequency and contrast). If the patient can answer the question correctly it can be assumed that the visual system has sufficiently resolved the pattern into its element bars, in order to determine their orientation. The spatial frequency of the gratings increases towards the bottom of the chart (lines get narrower) and the width of the finest bar for which the patient correctly performs the task can be used to calculate the MAR. the use of staircase method to bracket the MAR threshold should be used until an endpoint is reached (e.g. a certain number or reversals). Requirements for memory/ experience are limited through the use of two target alternatives: resolution acuity chart and detection acuity

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9
Q

I) Describe the phenomenon of “aliasing” in human vision.
ii) How do the measurements of MAD and MAR allow us to detect aliasing in human vision? What does the presence or absence of aliasing tell us about visual function?
(3 marks)
(Total 20 marks)

A

Aliasing is a phenomenon that results in ambiguous perception, as the stimulus is misrepresented by under sampling of the nervous system. It occurs as patterns beyond the resolution limit are detectable, but are seen incorrectly. The stimulus is too fine to be resolved by the sampling mosaic, so it becomes misrepresented as an alias of different frequency and orientation

ii
If MAD and MAR are the same value, then no aliasing is present. If MAD is more than MAR, then aliasing is present. The absence of aliasing tells us that there is an occurrence of optical filtering (optical problem causing reduced vision). If there is a presence of aliasing it means that there is neural under sampling (neural problem causing reduced vision). This is particularly important to find out in a px with cataract who may have other pathology eg amd as need to find out prior to surgery which is causing the low vision

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10
Q

Give 2 examples of eye conditions that can cause an aquired colour vision deficiency. And what deficiency is associated

A
  • AMD can cause a tritan defect
  • optic neuritis or retrobulbar neuritis can cause red green deficiencies
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11
Q

What is the stiles Crawford effect

A

Rays entering through the centre of the pupil are more likely to be absorbed by the retinal photoreceptors than peripheral rays

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12
Q

3 aspects of perception and cognition that may be assessed using. Describe how they are tested

A

Visual neglect
- inability to orientate, report or respond to sensory stimuli in a region of space contralateral to a cerebral lesion
- tested using cancellation testing and line bisection test

Visual perception
- brains ability to recognise, integrate and interpret information detected by different sensory stimuli
- tested using motor free vision perception to test for visual discrimination and spatial awareness
- ox-vps test can test for object recognition

Eye movement disorders
- maintaining primary position
- nystagmus
- phoria/tropia
- cover test
- fixation disparity
- motility
- saccades

Visual field loss
- standard perimetry

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13
Q

Theories of myopic growth mechanism

A

passive emmetropisation
- natural eye growth
- axial length grows other components grow accordingly
- produces emmetropic eye
- people with flatter corneas have longer eyes

Active
- eye grows towards an emmetropic state
- negative feedback
- hyperopia refocus
- axial length growth controlled by optics and environment

Refraction
- SV correction leaves hyperopia defocus

Choroid
- thinning causes reduced barrier to growth

Sclera
- decreased collagen synthesis
- decreased strength

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14
Q

Name and describe 5 different mono chromatic aberrations

A

Spherical aberration
- optical power of a lens is not constant across aperture
- positive lenses cause rays to be focused in front of the paraxial ray

Coma
- results from off axis objects
- rays divert differently across lens
- produces a comment shape image, either towards or away from the optical axis
- the more off axis the bigger the comet

Oblique astigmatism
- occurs due to difference in power between the tangential and saggital plane
- similar to on axis astigmatism but differs as the orientation of the focal lines are dependent on the location of the object

Field curvature
- as an object moves away from the axis on the object plane, the distance to the first principle point increases, and image distance changes
- eye compensates

Distortion
- occurs due to different amounts of magnification present across the lens
- pincushion distortion if the magnification increases at edge of the lens
- barrel distortion if magnification decreases

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15
Q

When can aliasing occur in normal vision, and abnormal conditions

A

Normal
- when spatial frequency is finer than 60 c/degree

Abnormal
- amblyopia
- amblyopic eye nearly as sensitive to contrast but at higher frequencies it is distorted
- amblyopia may be due to aliasing at some stage

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16
Q

Explain why a red filter lens may enable a px with anomalous colour vision to read the number on pseudoisochromatic test plate 5 marks

A
  • coloured filters the apparent brightness of colours
  • then don’t change or cure colour vision
  • the difference in brightness will allow for a discrimination to be made to compare colours
  • px can do this by using the filter monocularly or binocular
  • the ishihara test plates tend to test for red green deficiencies, so a red filter will allow for viewing of the red rays of light to appear brighter
17
Q

Disadvantages of colour filters

A
  • colour perception not Normal
  • reduced retinal illumination
  • effect on BV (fusion/stereo)
  • not always permitted
  • pulfrich effect
  • ## don’t work with mild CVD
18
Q

What is AI, machine learning and deep learning

A
  • Artificial intelligence is the development of computers to perform tasks which previously required human intelligence
  • machine learning refers to algorithms which improve at tasks when exposed to more outside data
  • deep learning refers to machine learning algorithms are arranged into multi-layer neural networks which can learn from the data itself
19
Q

Effect of deep learning on eye care

A

Diabetic ret
- excellent diagnostic performance
- systems which can give an automated classification based on millions of retinal photographs
- google are integrating an AI system into Indian hospital which has been trained on thousands of retinal images
- as effective as clinicians for diagnosing referable DR
- is able to identify associations between fundus image patterns and cardiovascular risks

AMD
- benefits for OCT
- OCT allows for 3D images
- AI can be used for classifiying the stage of AMD and can analyse the risk of conversion
- AI has been compared to the decision making of clinicians and found to be very similar

Glaucoma
- algorithms trained to detect glaucomatous disc signs
- can detect damage to the nerve fibre layer and compare it to normal scans
- can recognise clinically significant visual field loss
- can use IOP and VF data to improve forecasting
- in future can detect progressive structural optic nerve change

Refractive error
- predicted refractive error using AI interpretation of fundus photos

SCONE
- 2 yr project to build a Scottish database of retinal images
- aims to establish large scale cross sectional databases covering healthy and early disease states, including symptomatic and asymptomatic
- identify disease sooner
- improve referral accuracy
- triage prioritisation
- reduce cost of pathway between community and HES

Future work
- development of new algorithms for deep learning using retinal images
- image based staging and diagnosis of AMD
- expand the role of optom by lowing referral of non eye related conditions such as dementia and cardio vascular disease by detecting biomarkers and patterns

20
Q

2 types of chromatic aberration

A

Longitudinal
Traverse

21
Q

Effect of chromatic aberration on optical performance

A
  • generally doesn’t affect performance as eye doesn’t notice coloured fringes
  • eye is less sensitive to light of wavelengths towards the end of the visable spectrum making the fringes relatively dim
  • there is filtering of the image by the lens
22
Q

Von Kries mechanisms

A

Absorption
- lens becomes yellower
- blocks blue light
- when px gets cataract removed they notice the difference

Alteration system
- something alters the photoreceptors

Reduction system
- loss of photoreceptor

23
Q

What is heterochromic flicker photometry

A
  • measures luminance efficacy
  • eye most sensitive to 555nm
  • compares luminosity of 2 light sources
  • there is a rotating disc that chops the light
  • px will see this flickering
  • adjust until the sensation of the flickering is minimised
  • work out difference n perceived brightness
24
Q

Verriest classification of CVD

A

Mesopisation
- reduction in height of the luminous efficacy curve where everything looks dull

Scotopisation
- shift in peak of photopic sensitivity curve towards peak of the rod curve

Eccentration
- some eye conditions cause loss of central vision completely

25
Q

What is chromatopsia

A
  • coloured objects appear unnaturally coloured and colourless objects appear tinged with colour
  • px complains of seeing colours and ill know when it started

Causes
- drugs
- alcohol
- haemorrhages

26
Q

General symptoms neurological conditions

A

Physical
- upper and lower limb weakness

Functional
- difficulty performing every day tasks

Language
- unable to speak, can still receive information
- unable to retain information but can speak
- reading and writing ability

Cognition and memory
- ability to understand and remember

Emotional/psychological

27
Q

Health concerns with myopia

A
  • PVD
  • retinal detachment
  • glaucoma
  • cataracts
28
Q

Myopia control options and efficacy

A

Distance under correction
- doesn’t work
- greater myopic progression

Bifocals
- reduces accommodation demand
- reduces accommodation lag
- 0-50% reduction

Progressive lenses.
- caused more growth than hyperopic defocus

DIMS
- 52% reduction

Ortho-k
- 30-60% reduction

Dual focus lenses
- alters peripheral corneal power
- 50% reduction

Atropine
- side effects
- thickening choroid
- 40% reduction

29
Q

Wet AMD treatments

A

Photodynamic therapy
Anti VEGF
Macular translocation

30
Q

Evidence based advice on macushield capsules

A
  • AREDS
  • found that there is a reduced risk of progression in px that take the supplements
  • statistically significant result compared to placebo
  • concluded that px should take supplements similar to AREDS antioxidant plus zinc formula
  • no adverse effects were noted
  • reduced risk of advanced dry AMD and reduced risk of progressing to neovascular
31
Q

What is the self efficacy model, how can it be applied to management

A
  • Self efficacy is regarded as the primary factor in adjustment to vision loss

Model
- loss of sight reduces ability to do simple tasks
- loss of control and self esteem
- depression

Treatment
- prevent loss of competence
- start rehab as soon as possible
- get px performing old tasks at an early stage
- simple techniques with positive feedback
- tasks which show rapid progression
- attribute failure to external influence

32
Q

What to mention for environmental design

A

Simple things
- move tv away from windows
- sit closer to tv
- location of lights for reading/glare
- sit to one side for hemianopia?
- hard floor

Colours
- light matte walls
- dark paint round doors and skirting
- lighter door with contrasting handle
- contrasting light switch

Features to aid LV
- wide doors
- sliding doors
- auditory indicators
- handrails
- tactile elements
- no projections
- strip lighting
- floor plans in public places

Hinders LV
- no signs
- glass doors
- trip hazards

33
Q

Clinical tests to explore ocular risk factors for myopia

A

Axial length
- IOL master
- 5 readings per eye
- very accurate
- more sensitive than SER
SER
History and symptoms for risk factor data
Reading distance
FUNDUS photo
Prescription

34
Q

What structures differ in a myopic px

A

Axial length
AC chamber depth
Lens
Vitreous chamber depth
Cornea

35
Q

Advantages/disadvantages of 2 myopia control tx

A

Ortho-K
- no need for lens during the day
- px can swim etc and contact sports

  • has to wear every night
  • potentially less effective
  • more effective in younger children

Atropine
- increases choroidal thickness
- totally paralyses accommodation

  • side effects
  • glare/photophobia