past paper set 2 Flashcards

1
Q

p gingivalis virulence factors

A

biofilm formation
LPS endotoxin
fimbriae - host tissue adhesion and invasion
proteases
capsule polysaccharide and outer membrane vesicles

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2
Q

c albicans virulence factors

A

hyphae (morphological change and host invasion)

proteases

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3
Q

s mutans virulence factors

A
binding proteins - glucosyl and frucosyltransferases
glucans (communication and adhesion)
sugar modifying enzymes
polysaccharides
acid tolerance and adaption (ATPase)
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4
Q

LA mechanism

A

prevents action potentials through the voltage gated Na+ channels

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5
Q

sugar substitutes

A
mannitol
xylitol
sorbitol
aspartame
saccharin
sucralose
cyclamates
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6
Q

salivary proteins

A
amylase
cystatin
gustin
histatin
Igs
lactoferrin
lactoperoxidase
lipase
lysozyme
mucoproteins
'plasma proteins'
PRPs
statherins
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7
Q

enzymes in saliva

A

amylase
lactoperoxidase
lysozyme

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8
Q

fcts of tongue

A
speech
mastication
mechanical cleansing
taste
protective reflex
kissing
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9
Q

Bell’s palsy

A

acute unilateral facial palsy with unknown cause

  • most resolve spontaneously within a few wks
  • neurological opinion if severe
  • CS (+/- antiviral)
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10
Q

macrocytic anaemia

A

reduced B12, folate

reticulocytes

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11
Q

normocytic anaemia

A

bleed

chronic disease

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12
Q

short-term adrenal suppression effects

A

mood disturbance

insomnia

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13
Q

faint

A

LOC due to hypotension causing hypoperfusion of the brain due to reduced O2

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14
Q

heart attack

A

MI due to atheroma causing arterial lumen occlusion

reduced O2 causing tissue necrosis of area

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15
Q

detecting a conventional bridge debond

A

place probe under pontic and apply pressure coronally
- abutment may move
- saliva bubbles may be seen at margin
can you pass floss underneath?
if debonded for some time, abutment may be visibly grossly carious
may see caries radiographically underneath
can section into smaller pieces and check for adhesiveness

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16
Q

features that may lead to conventional bridge failure

A

poor crown prep, insufficient reduction or crown margins finished subgingivally
retainers not prepped to common PofI
lack of sufficient ferrule for crown
inadequate root surface area for support, Ante’s law
poor moisture control during cementation

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17
Q

implant considerations

A
quantity of bone
quality of bone
position of existing teeth - rotations, angulations
OH
proximity to anatomical features
smoking 
MH
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18
Q

extrinsic staining

A

diet
smoking
CHX
Fe supplement

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19
Q

intrinsic staining

A

F
non-vital
tetracycline
physiological age changes

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20
Q

Glickmans theory

A

inflammation spreads from gingivae into supporting PDL to produce a vertical bony defect, which local trauma exacerbates

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21
Q

Waerhang’s theory

A

plaque causing bone destruction of a 2mm radius, not big enough to destroy entire width so angular defect

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22
Q

common causes of vertical defect

A
trauma
calculus
subgingival plaque
occlusion
overhanging Rxs
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23
Q

features in a parotid swelling that would make you suspect malignancy

A

fixed to underlying structures
firm
growing
unilateral

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24
Q

fluorosis appearance

A

diffuse, mottled
pitting
yellow/brown discolouration

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25
clinical governance
a framework through which NHS organisations are accountable to continuously improve quality of services and safeguard standards of care achieved by creating an env where excellence in clinical care can flourish
26
divisions of NHS dentistry scotland
HDS PDS GDS
27
components of CG
``` clinical audit clinical effectiveness research and development openness risk management education and training ```
28
ABs may not be successful for perio
``` may be inactivated may be resisted by biofilms superinfection could occur may not reach site of disease activity may have inadequate drug concentration and retention ```
29
axis of rotation when denture under load
line drawn between clasps on opposite sides of the arch, that form axis about which the denture will rotate
30
improving retention and stability in a loose Cu
relining implant retained prosthesis replacement
31
fluconazole and midazolam
increases sedation
32
postural hypotension
fall in cardiac output poor venous return venous pooling in legs fall in stroke volume
33
what factors can make implant placement difficult?
lack of space aesthetic zone prosthesis may be involved in guidance
34
what does miconazole have antimicrobial action against?
candida | staphylococci
35
minimising RBB debond
pick tooth with large bonding area for abutment | cantilever design for anterior sextant
36
faults causing debond
poor moisture control during cementation unfavourable occlusion poor E quality on abutment inadequate coverage of abutment
37
what is used for metal wing of RRB?
CoCr
38
why is PDD a contraindication for SDA?
drifting of PD compromised teeth under occlusal load loss of alveolar bone leading to a compromised denture-bearing area in the long term loss of space (neutral zone) for denture teeth in the long-term
39
host evasion mechanisms of p gingivalis
gingipains adhesions fimbriae capsular polysaccharide
40
beclometasone inhaler
increased caries risk increased candida risk dry mouth
41
salbutamol and acid erosion of teeth
dry mouth reduced salivary protections against acids pH change of mouth GORD
42
advice for inhaler usage
20mins before/after brushing rinse mouth with water after use spacer
43
class 3 miller's classification of recession
marginal tissue recession that extends to or beyond the mucogingival jct, with PD AL in the interdental area or malpositioning of teeth
44
class 4 miller's classification of recession
marginal tissue recession that extends to or beyond the mucogingival jct, with severe bone or ST loss in the ID area and/or severe malpositioning of teeth
45
IO signs of bruxism
tongue scalloping wear facets linea alba
46
local causes of tooth mobility
periodontitis root resorption PA pathology
47
factors influencing tooth mobility
width of PDL height of PDL inflammation number, shape and length of roots
48
most freq causes of TN
areas of focal demyelination on the peripheral nerve | aberrant intra-cranial artery in the cerebellopontine region
49
MS S+S
intention tremor | balance impairment - loss of proprioception
50
brain tumour S+S
seizures | memory problems
51
viruses linked to Bells palsy
HSV1 | VZV
52
faint physiology
reduction in blood returning to heart reduction in bp, heart beats harder and faster (ANS) brain responds inappropriately and causes further drop in bp - vasovagal faint
53
differential diagnosis for burning tongue
oral dysaesthesia (BMS) subclinical infection glossopharyngeal neuralgia
54
primary BMS
no underlying | damage to nerves that control pain/taste?
55
possible causes of BMS
``` anxiety/depression haematinic deficiencies parafct hormonal changes - DM, thyroid allergy xerostomia acid reflux ```
56
swelling PD pocket
trauma blockage increased tissue tone of pocket following NST
57
oral manifestations of herpes
PHG herpes labialis KS hairy leukoplakia
58
oral diseases caused by EBV
hairy leukoplakia infectious mononucleosis (glandular fever) Burkitt's lymphoma, nasopharyngeal cancer, OSCC
59
SG tumours incidence in parotid gland
``` pleomorphic adenoma Warthin's tumour adenoid cystic carcinoma (most common minor SG tumour) mucoepidermoid carcinoma acinic cell carcinoma ```
60
how does F have a bacteriocidal effect?
inhibits ATPase in the s mutans meaning it interrupts acid tolerance
61
SR of a salivary duct calculus
``` LA incise FOM over duct to expose duct place a holding suture behind calculi to prevent movement further along the duct incise at duct orifice or along duct squeeze out stone suction haemostasis, suture wound, POI ```
62
RFs for creating OAC
proximity of tooth to MS, large sinus abscess/cyst associated with tooth extracted hypercementosis difficult ext divergent roots poor ext technique with excessive apical pressure
63
MCV
80-97
64
metronidazole mechanism
inhibits nucleic acid synthesis by disrupting DNA of microbial cells
65
criteria for MRONJ diagnosis
hx/tx with antiangiogenics/antiresorptives such as bisphosphonates and denosumab exposed/non-healing bone >8wks no hx of radio to H+N region no obvious metastatic disease of the jaws
66
pain caused by dentine hypersensitivity - hydrodynamic theory
D has no direct innervation, v few fibres may be present in the inner 1/3, pulp is highly innervated stimulus applied to outside of D causes movement of dentinal fluid movement of fluid at pulpal end of tubules stimulates nerve endings in inner 1/3 and at the pulp, causing pain blocking dentinal tubules (and therefore prevention of stimuli affecting dentinal fluid) prevents pain
67
adhesive bridge failure
``` cementation fail lack of moisture control divergent pathways parafct lack of regard for occlusion poorly retentive prep trauma caries ```
68
why does cantilever have better prognosis than F-F for upper anteriors?
not subject to forces from divergent pathways only involves one natural tooth less worry about parallelism less occlusal interference
69
risks of decalcification
``` poor aesthetics sensitivity (pain) debonding poor tx outcome could progress to gross caries - loss of vitality ```
70
diagnostic features of fluorosis
severity is F dose dependent - white areas/enamel opacity to areas of discolouration, pitting and hypoplastic effects distribution on tooth surface is time dependent, areas affected will correlate with E formation at time of excess consumption - can help distinguish severe fluorosis from AI
71
causes of amalgam fracrure
CSM finished under centric stop CSMA <70 degrees amalgam thickness <2mm deep occlusally or <1mm deep elsewhere secondary caries pt occluded on it before it was fully set too much liquid mercury in the amalgam mix creep trauma high Rx
72
preventing amalgam fracture
appropriate cavity prep and Rx design (margins not under centric stops, margins >70 degrees, ideally 90 degrees) correct thickness of amalgam appropriate pt advice after seating - avoid eating on it for 24hrs to allow it to set properly good OHI, diet advice and F to reduce caries risk use amalgam capsules containing pre-set amounts of mercury and alloy powder to minimise risks of incorrect proportions being used during mixing
73
amalgam setting reaction
Ag3Sn + Hg ---> Ag3Sn + Ag2Hg3 + Sn7Hg9 | y +Hg ---> y + y1 + y2
74
copper enriched amalgam equations
y2 + AgCu ---> Cu6Sn5 +y1 | OR AgSnCu + Hg ---> AgSnCu + y1 + Cu6Sn5
75
y2 phase properties
poor strength and abrasion resistance
76
modern amalgam and copper
has high Cu (>12%) content to reduce y2 | copper reacts with tin to reduce availability of tin for y2 phase
77
pathological response to traumatic occlusion
PDL widens, tooth symptomatic/widening of PDL space fails to stabilise tooth not adequately compensating for the changes
78
assessing where a high Rx is
articulating paper - shimstock 8um in Millers forceps diagnostic mounting of casts visual examination floss
79
tx options for mobile teeth presenting with widened PDL space
control any plaque-induced inflammation - increases tissue tone and prevents any bone or AL that may contribute to mobility occlusal correction - selective grinding, replacement Rxs, ortho splinting - temp/long term stabilisation of v mobile teeth. May make harder to clean so not ideal if PD involvement. May also mask underlying disease progression. Not a tx for PDD
80
CHX mechsnism
dicationic 1 cation adheres to pellicle and 1 cation disrupts bacterial membrane + charged CHX attracted to - charged phospholipids in bacterial cell wall CHX binding causes the cell wall to rupture and allows fluid to leak from the bacteria, leading to cell lysis and death
81
CHX substantivity
12hrs
82
surgicel
oxidised cellulose mesh that absorbs blood and swells into a gelatinous mass that aids clotting resorbable has a degree of bactericidal effect careful for L8s - acidic and can damage nerve
83
kaltostat
calcium sodium alginate dressing, forms a hydrophillic gel with wound exudate to maintain a moist wound interface and prevent tissue maceration
84
bone wax
sterile mix of beeswax, paraffin and a softening agent (isopropyl palmitate) used to mechanically plug bleeding vascular channels in bone affects osteogenesis so not used in regions that may regenerate
85
immediate bleeding
within 48hrs likely rebound or reactionary effect of tx as the vasoconstrictors wear off, sutures are lost or wound is traumatised by the pt
86
later post op bleeding
3-7days | more likely due to an infection, usually a mild ooze but can be more serious
87
indications for Warfarin
heart surgery - prosthetic replacement heart valve coronary heart disease (post-MI, angina) stroke prevention for pts w AF thromboembolic disease e.g. DVT, PE
88
how to restore excessive FWS with worn dentures
occlusal pivots or restore occlusal surface with autopolymerising acrylic resin
89
oral signs of anaemia
``` pale mucosa mucosal atrophy atrophic glossitis stomatitis angular cheilitis burning ulcers ```
90
6 basic pt values
``` working together for pts respect and dignity commitment to quality of care compassion improving lives everyone counts ```
91
plasma cell gingivitis
rare, benign diffuse and massive infiltration of plasma cells into the sub-epithelial gingival tissue (CT) diffuse enlargement with oedematous swelling of gingivae in anterior region unknown aetiology - is it due to a hypersensitivity reaction to an allergen? possibly due to neoplasia
92
meds linked to LTRs
diuretics - bendroflumethiazide anti-hypertensives - B blockers, ACE inhibitors NSAIDs antimalarials - hydroxychloroquine
93
when may fordyce spots be more noticeable?
thinning of mucosa | more aware of OH due to recent dental tx
94
what was used before MTA to seal end of root?
amalgam
95
what can amalgam be spread by?
Langerhans cells (APCs)
96
management of ROU in HDS
investigstions - FBC, exclusion diet/patch test - doesn't give definitive info exclude coeliac and refer to gastroenterology if IBD suspected systemic therapy if not controlled with topical - prednisolone
97
yellow base of ulcer not present
area still being traumatised
98
OSF
associated with betel chewing | epithelial inflammatory reaction and progressive fibrosis of submucosal tissue
99
actinic cheilitis compared to IO carcinoma prognosis
much better later metastasis (to submental nodes) and slow prognosis cure rate high and easy to monitor
100
differential diagnoses of neck swelling
``` lymphoma carotid body tumour brachial cyst sebaceous cyst metastatic cancer in neck node ```
101
how does cancer differ from an infective cause of neck swelling?
slow enlargement painless (gradual stretching of fascia) not fluctuant - but fixation can occur in chronic infection to be fibrosed
102
complications of mumps
encephalitis pancreatitiis meningitis deafness
103
nebuliser
liquid medicine into a fine mist which you then breathe in
104
saliva substitutes
glandosane saliva orthana salivese biotene
105
perivascular infiltrate
the mononuclear inflammatory cell infiltrate around the venules indicates a delayed type of hypersensitivity reaction
106
hyperplasia
increase in all layers of epithelium
107
why are there no Tzank cells in pemphigoid?
no weakening of attachment (acantholysis)
108
pigmentary incontinence
melanin pigment leaking out into the LP | leaks out of epithelium into tissue and stains
109
grading
resemblance of the cells to the tissue of origin | ability to carry out same fct as tissue of origin
110
what is mucous retention cyst lined by?
epithelium
111
where is mucous retention cyst more common?
upper lip in older adults
112
what is the most common site of pleomorphic adenoma of minor SGs?
palate
113
adenoid cystic carcinoma issues
local recurrence - difficult to determine clinically how far the tumour has spread and if surgical excision is incomplete most likely metastasis - haematogenous spread to the lungs which is unusual for a carcinoma. LN metastasis to neck nodes is unusual
114
what to ask for in a pus aspirate?
culture and susceptibility testinf
115
safety elements when transporting materials to lab
needles must be removed from syringes and disposed of in a sharps safe waste container transport in leak-proof containers and protected against damage need absorbant material in case specimen leaks at least 2 leakproof solid containers distinct labelling on outside and practice address
116
common bacteria isolated from acute dentoalveolar abscess
streptococci - s anginosus | strict anaerobes e.g. prevotella intermedia
117
role of pus sampling in AM stewardshipq
can take several days to obtain a C+S report from a pus aspirate and the immediate benefit of taking a specimen may not be readily apparent for most patients but accumulation of data on susceptibility patterns helps inform the production of empiric AB prescribing by providing up to date surveillance data as patterns of AM resistance can change over time also not all pts will respond as expected to tx and microbial identification and susceptibility testing can help inform clinical decisions
118
principles of in pt management for acute dental infection
1 - assessment of airway 2 - S+S of sepsis and resuscitation as appropriate 3 - IV ABs - benzyl penicillin and metronidazole 4 - I+D under GA (+ ext of infected teeth) 5 - pus aspirate for C+S testing
119
denture-induced stomatitis - Newton's Classification
type 1 - pinpoint hyperaemia (localised erythema) type 2 - diffuse erythema type 3 - granular erythema (papillary hyperplasia)
120
what should you consider if there are unusual species in the microbiology report?
concern that pt is IC and possibly HIV+ | - refer urgently
121
EM
hypersensitivity type 3 skin reaction to infection/drug exposure mediated immune complexes deposited in superficial layer of skin and oral mucous membrane - >50% cases due to HSV (1>2)
122
drugs predisposing to EM
``` NSAIDs penicillin sulphonamides nitrofurantoin phenothiazines anticonvulsants ```
123
long-term potential sequelae of shingles
post-herpetic neuralgia
124
replacement options for central incisor crown fractured completely off to root at short notice?
provisional overdenture provisional post-crown vacuum formed splint w tooth rebond fractured crown
125
clinical signs of erosion
loss of surface detail smooth or polished surfaces exposed D cupping
126
implant bone dimensions
1.5mm horizontal bone round implant 3mm between implants >5mm between bone crest and CP
127
check if a bridge has debonded
``` probe visually mobility push and check for air bubbles floss ```
128
tx reversible pulpitis
removal of caries or other causative factor and Rxs
129
nerve fibres most susceptible to LA
Ad, C, Ab, Aa | smaller nerves affected quicker
130
LA constituents
``` base hydrochloride (anaesthetic agent) vasoconstrictor fungicide reducing agent preservative ```
131
what are molars better with than a post?
pulp chamber retention
132
primer
HEMA supports collagen fibrils and makes space for bond
133
inorganic content % of dentine
calcium hydroxyapatite 70%
134
advantages of amalgam
``` strong abrasion resistance corrosion improves marginal seal radiopaque long-lasting cheap easy quick ```
135
disadvantages of amalgam
``` excessive tooth prep as not bonded aesthetics mercury toxicity creep weak in thin sections high thermal conductivity allergy tattoo galvanic reaction ```
136
criteria before you obturate
asymptomatic canals dried chemomechanical disinfection completed satisfactorily
137
sealer fct
fill lateral canals and the space between tooth and GP | hermetic seal
138
why obturate?
seal remaining bacteria provide apical and coronal seal prevent reinfection
139
what % of U6s have an MB2 canal?
93%
140
advantages of crown down technique?
``` removes bulk of infected tissue reservoir for irrigant keeps reference point for WL make SL access easier limit spread of infected material at apical foramen ```
141
cementing a porcelain
silane coupling agent covalent bonds to oxide groups on porcelain surface (hydrophilic) hydrophobic C=C reacts with silane in composite - etch in lab w HF acid
142
what should you do before modifying your cavity prep/finishing?
choose material
143
signs of occlusal trauma
``` pain not explained by infection fracture of Rxs or teeth mobility NCTSL TMD scalloping, pronounced linea alba ```
144
monitoring TW
BEWE index Smith and Knight photos study models
145
what % of adults have TW?
60%
146
features of a cavity for composite
no US E no sharp internal LAs bevel CMSA to increase area for bonding
147
techniques for placing composite
flowable at base to reduce contraction stress incremental placement to have a low configuration factor no more than 2mm increments to avoid soggy bottom
148
cavity features for amalgam
``` UCs for retention other retention factors e.g. lock and key, grooves >2mm depth for sufficient strength flat occlusal floor CSMA 90-120 degrees no US E ```
149
advantages of Protaper over Kfiles
shape memory reduced lateral pressure so reduced risk of ledge, zip etc reduced number of instruments needed increased cutting efficiency
150
reasons a file may separate
cyclic fatigue torsional fatigue flexural stress torsional stress
151
consequences of amalgam overhang
secondary caries gingivitis and PDD may also lead to amalgam fracture in thin section
152
fcts of a facebow
mount upper casts position upper cast give relationship of upper occlusal plane to condyle transfer angle of maxillary occlusal plane to a horizontal reference plane
153
anterior guidance preferred why
easy to reproduce protect teeth and Rxs easy on muscles
154
all metal crown reductions
axial 0.5mm NFC 0.5mm FC 1.5mm chamfer 0.5mm
155
MCC reductions
``` axial 1.5mm FC 2mm NFC 1.5mm chamfer 0.5mm shoulder 1.5mm ```
156
ceramic crown reductions
axial 1mm NFC 1mm FC 1.5mm shoulder 1mm
157
acrylic faults during production
contraction porosity - too much monomer and poor pressure gaseous porosity - monomer boiled off granular porosity - not enough monomer crazing - too much stress
158
GIC composition
powder - fluoroaluminasilicate glass | liquid - polyacrylic acid
159
why is RMGI not good as a luting agent?
contains HEMA which absorbs water and swells | cytotoxic
160
tempbond constituents
base - zinc oxide, starch and mineral oil | accelerator - EBA, eugenol, carunba wax
161
zirconia bonding
cannot be etched, will not chemically bond | retention is micromechanical
162
why are lithium disilicate crowns strong?
crystals stop crack propagation
163
preventing postural hypotension
allow chair to sit up gradually and encourage pt to take their time and take deep breaths
164
GABA
gamma amino butyric acid | inhibitory neurotransmitter in CNS
165
1/2 life of midazolam
90-150mins
166
ASA classifications
``` 1 - fit and well 2 - mild systemic disease 3 - severe systemic disease 4 - severe systemic disease with threat to life 5 - moribund 6 - brain dead ```
167
managing a knife edge ridge impressions
take primary imp as normal for master, manage similar to a flabby ridge - take a mucocompressive imp then relieve areas around the knife-edge with a scalpel then take a 2nd mucostatic imp with a light body material
168
soft lining
may be used on healthy mucosa as a cushion/shock absorber in a reline or for atrophic/knife edge ridges
169
tissue conditioner
used in unhealthy/ulcerated mucosa to aid healing | also dissipates forces but is a more short-term option
170
fct impression
used w a tissue conditioner material is applied and pt wears the denture and imp in fct for <24hrs they return and imp is sent to lab for a reline
171
improving denture retention
``` remaking rebase reline implant retained precision attachments ```
172
why is the buccal shelf used for support?
it is non-resorbable
173
shade factors
value hue chroma translucency
174
disadvantages of immediate dentures
resorption makes fit poor requires reline/rebase no trial stage difficult with surgical XLA
175
clot
vasoconstriction platelet plug fibrin clot
176
aspirin action
inhibits platelet aggregation
177
heparin action
accelerates the rate of neutralisation of certain activated CFs by AT
178
stages of development of a biofilm - ACACD
``` adhesion colonisation accumulation complex dispersal ```
179
virulence factors for p gingivalis - PAGET
``` proteases adhesins gingipains endotoxins toxic byproducts ```
180
virulence factors for c albicans GAMES
``` germ tube formation adhesins metabolic acids EC enzymes switching mechanism ```
181
virulence factors of s mutans ASAP
adhesins sugar modifier enzymes acid tolerance polysaccharide
182
swallowing liquids
from mouth | posterior oral seal
183
swallowing solids
``` oral cavity continuous with pharynx ingestion stage 1 transport mechanical processing stage 2 transport swallowing ```
184
stages of tooth development
``` initiation morphogenesis cytodifferentiation matrix secretion root formation ```
185
4 parts of the late bell stage
inner enamel epithelium external enamel epithelium stellate reticulum stratum intermedium
186
PD abscess
acute exacerbation of an existing PD pocket e.g. trauma or obstruction
187
managing traumatic occlusion in a pt w PDD
HPT | bite raising appliance to be worn at night
188
factors influencing localised mobility
``` existing PDD traumatic occlusion causing widening of the PDL morphology and length of rooths PA bone loss resorption trauma ```
189
NG microbiology
fusospirochaetal complex - treponema denticola, prevotella intermedia
190
bone loss radius of destruction of plaque
about 2mm
191
SEs of CHX
stain taste disturbance anaphylaxis interacts with SLS
192
local factors for gingival recession
``` PDD habits traumatic toothbrushing abrasive TP high fraenal attachment crowding traumatic occlusion orthodontics ```
193
managing localised recession
``` atraumatic TB technique minimise other RFs monitor tx sensitivity free gingival graft (from palate) root coverage surgery ```
194
indications for regenerative PD surgery
2 and 3 walled defects G2 furcation in L teeth G2 buccal furcation in U molars
195
diabetes as a RF for PDD - WIPA
poor wound healing both pro-inflammatory diseases impaired PMN fct advanced glycation end (AGE) products causing increased tissue destruction
196
tests for diabetes
RPG >11.1mmol/L FPG >7mmol/L = on 2 occs GTT
197
HbA1c ideal
48mmol/L or below
198
smoking affects PD tissues CCEB
impaired chemotaxis and phagocytosis affects cytokine production affects enzyme catalases blood flow restricted
199
IL-1
a pro-inflammatory cytokine | stimulates the release of enzymes and OCs causing increased tissue destruction
200
NST may not be successful
``` inadequate RSI furcation/angular defects that are difficult to adequately clean motile anaerobes moving into tissues pt not adhering to OHI pt IC ```
201
topical effects of F
reduce acid production by plaque promote remineralisation bactericidal remineralised E as fluorapatite
202
pulp tx failure
clinically - mobility, pain, fistula | radiographically - radiolucency, resorption, furcation
203
cause of AI
gene mutation of amelogenin and enamelin proteins
204
what can HSV1 reactivation cause?
herpes labialis (15-30% pts) or bells palsy
205
indications for SSC
``` MR broken down restore primary molars MIH after pulp tx space maintenance ```
206
health issues associated w Down syndrome
``` VSD epilepsy leukaemia hearing problems cataracts ```
207
external inflammatory resorption pathogenesis
progressive resorption of external root surface due to damaged PDL resulting in necrotic pulp tissue via dentinal tubules pH low therefore acidic so OCs stimulated - cementum and bone resorption
208
clinical external inflammatory resorption
- to sensibility test may be TTP may be mobile
209
radiograph external inflammatory resorption
tramlines intact but loss of LD | defect moves with a 2nd radiographic view
210
autism triad of impairment
communication social imagination social interaction
211
other features of autism
``` sensory sensitivity obsessive learning difficulties epilepsy tubular sclerosis ```
212
indications for FS
high caries risk medically compromised pts caries in primary dentition caries in permanent dentition
213
types of CP
spastic ataxic athetoid mixed hemiplegia diplegia paraplegia quadriplegia
214
CF dental
thick saliva so reduced caries but increased calculus E defects delayed eruption avoid GA and sedation
215
biopsy LP
symptomatic smokers erosive
216
2 ways trigeminal neuralgia can occur
demyelination causing CN5 ischaemia | aberrant arteriole in cerebello-pontine region lying on the nerve - blood pulsing causes nerve activation
217
anaemia
reduction in oxygen carrying capacity of the blood due to a deficiency of Hb or rbcs
218
oral signs of anaemia
ROU candida glossitis (smooth iron, beefy vit B12/folate, burning mouth, mucosal pallor)
219
tx of plasma cell gingivitis
prevent exposure to allergen e.g. SLS, benzoates, cinnamon, through dietary advice
220
managing xerostomia
underlying condition prevention (OHI, F, diet) symptomatic relief - substitutes
221
ways ABs work
``` cell wall destruction protein synthesis inhibition cell membrane inhibition DNA synthesis inhibition DNA replication inhibition ```
222
disadvantages of ABs
resistance GI upset drug interactions
223
mechanisms of AB resistance
drug reaction altered target site reduced accumulation altered metabolism
224
U vs L MND
"upper spares upper" everything above eyebrows still fcts in U (CVA) U part of facial motor nucleus receives both crossed and uncrossed fibres so the frontalis and orbicularis oculi muscles are spared - can furrow brow
225
causes of LMN disease
``` reactivated HSV causing bells palsy mastoiditis trauma parotid tumour LA HIV ```
226
management of LMN disease
80% resolve in weeks prednisolone to reduce swelling of facial nerve at stylomastoid foramen eye protection
227
common causes of TMD
stress parafct occlusal discrepancies trauma
228
TMJ nerve supply
auriculotemporal and masseteric branches of V3
229
BRA
minimise parafct habits minimise load on TMJ provide stable occlusion eliminate occlusal interferences
230
diseases caused by coxsackie virus
HFM, herpangina, haemorrhagic conjunctivitis, aseptic meningitis
231
EBV fdiseases
hairy leukoplakia burkitt's lympgoma IM
232
asthma
reversible airflow obstruction - smooth muscle contraction - inflamed mucosa causing swelling - increased mucus secretion
233
dental aspects of asthma
``` increased candida - steroid effects increased erosion (intrinsic GORD, extrinsic meds), reduction in saliva exacerbating both --->rinse w water, use spacer possible allergy to colophony in FV MEs for asthma attacks ```
234
S+S oral cancer
sites - lat tongue, FOM, SP signs - unexplained >3wks white/red patch, ulcer, swelling, hoarseness, unexplained mobility ulcer - rolled border, indurated, bleeding, numbness, pain
235
necrotising sialometaplasia histology
``` slough inflammation hyperplastic metaplasia necrosisq ```
236
OFG histology
non-caseating GCs oedema dilated lymph
237
radio risks
``` mucositis xerostomia ORN increased infection poor wound healing ```