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Disease summaries > Past paper questions > Flashcards

Past paper questions Flashcards

1
Q

Which Abx inhibit protein synthesis

A

Macrolides - Erythromycin
Aminoglyclaides - Gentamicin
Tetracyclines - Tetracycline + Doxycycline

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2
Q

Which Abx inhibit cell wall synthesis

A

Cephalosporins - Ceftriaxone
Penicillins
Vancomycin

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3
Q

Which Abx inhibit DNA replication

A

Ciprofloaxcin

Levofloxacin

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4
Q

What determines haemodynamic compromise

A

Systolic BP < 90

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5
Q

Hyperkalaemia ECG

A

Tall T waves
Prolonged PR interval
Wide QRS
Absent P

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6
Q

Hypokalaemia ECG

A

U waves
Inverted T waves
Prolonged PR
ST depression

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7
Q

Features of carinoid syndrome

A

Flushing
Diarrhoea
Cardiac involvement

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8
Q

What can cause hyperglycaemia in Diabetics

A

Thiazides

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9
Q

Presentation of PCRV

A 
Thrombosis 
headache 
dizzy 
visual disturbance 
vertigo 
tinnitus 
IC
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10
Q

Amitryptiline A/E

A

Dry mouth
confusion
urinary retention
blurring vision

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11
Q

Myeloma presentation

A

C - Hypercalcaemia
R - Renal imparement (Free light chains)
A - Anaemia + Pancytopenia
B - Lytic bone lesions / Fractures / Vertebral collapse

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12
Q

Blood glucose measurements

A

Fasting > 5.5
Pre diabetes (5.6 - 7)
Random > 11
HbA1c > 48

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13
Q

6 in 1 vaccination

A 
Diptheria 
tetanus 
polio 
Hep B 
Haemophilius influenzae B 
Whooping cough
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14
Q

Myeloproliferative disorders

  • cells increased
  • assosciated mutation
A

Haemopoetic stem cells –> Primary myelofibrosis

Erythroid cells –> PCV

Megakarocyte –> Essental thrombocythaemia

JAK2 MUTATION

Has the potential to cause AML

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15
Q

What are the Ab for Hashimotos thyroditis

A

Anti - thyroperoxidase Ab

Anti - thyroglobulin Ab

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16
Q

Causes of primary hypothyroid

A

Hashimotos
Iodine deficiency
Drug induced - lithium
Tx for hyperthyroidism

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17
Q

SSRI’s adverse effects

A 
GI upset 
weight disturbance 
Hyponatraemia 
suicidal thoughts 
Prolong QT - Citalopram 
Increased risk of bleeding
18
Q

Gastric ulcers

A

Pain when eating

Pain occurs 30mins - 1hr after a meal

19
Q

Duodenal ulcer

A

Pain relieved by eating
Occurs 2-3hrs after meal
Night pain
Weight gain

20
Q

TTP Presentation

A 
Haemolytic anaemia 
decreased platelts 
AKI 
Headache / palsies / seizure - Neuro sx
Fever 
Schistocytes
21
Q

Exacerbation of COPD common organisms

A
  1. Haemophilius Influenzae

2. Strep pneumonia

22
Q

Causes of hypoadrenalism

  • Primary
  • Secondary
A
  • Addisons
  • Surgery
  • Infection
  • Loss of blood flow
  • Long term steroid usage
23
Q

Gold standard Ix for Acromegaly

A

Oral glucose tolerance test

24
Q

Carcinoid syndrome

  • secretion
  • presentation
  • tx
A

Insulin / ACTH / Serotonin / Bradykinin

Bronchoconstriction
Hyperglycaemia

SST analogue

25
Q

Prophlaxis for sickle cell crisis

A

Hydroxcarbamide

26
Q

Tx for sideroblastic anaemia

A

Pyridoxine

27
Q

Acute liver failure charecteristics

A

No previous liver disease
INR > 1.5
Onset < 26wks
Mental alteration - HE

28
Q

Inheritance pattern for Haemophillia

A

X - lined recessive

29
Q

COPD Tx pathway

A

SABA/SAMA

Asthma respose - LABA + ICS

NO Asthma response - LABA + LAMA

Oral theophlinne

Long term O2

30
Q

Spinal cord compression presentation

A

UMN Sx - Below level of lesion

LMN Sx - At level of lesion

31
Q

Describe Strep Pneumonia

A

Gram +ve diplococcus

32
Q

Sensitivity

A

Proportion of pwople with a disease who test positive

33
Q

Speicific

A

Proportion of people who don’t have the disease who test negative

34
Q

+ve predicted value

A

Proportion of people who test +ve who have the condition

35
Q

-ve predicted value

A

Proportion of people who test ive who don’t have the condition

36
Q

Primary prevention

A

Decrease initial occurence
NHS Health check
Stain use
Immunisation

37
Q

Secondary prevention

A

Tx disease to halt progression + prevent long term problems

Anti platelts post MI

38
Q

Tertiary prevention

A

Reduce impact of the disease + improve QOL

39
Q

Complicate UTI

A 
Men 
children 
Pregnant woman 
Recurrent UTI 
Structural abnormality
40
Q

WPWS ECG

A

Short PR interval
wide QRS
Delta wave

Disease summaries (9 decks)

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