Past paper questions Flashcards
Which Abx inhibit protein synthesis
Macrolides - Erythromycin
Aminoglyclaides - Gentamicin
Tetracyclines - Tetracycline + Doxycycline
Which Abx inhibit cell wall synthesis
Cephalosporins - Ceftriaxone
Penicillins
Vancomycin
Which Abx inhibit DNA replication
Ciprofloaxcin
Levofloxacin
What determines haemodynamic compromise
Systolic BP < 90
Hyperkalaemia ECG
Tall T waves
Prolonged PR interval
Wide QRS
Absent P
Hypokalaemia ECG
U waves
Inverted T waves
Prolonged PR
ST depression
Features of carinoid syndrome
Flushing
Diarrhoea
Cardiac involvement
What can cause hyperglycaemia in Diabetics
Thiazides
Presentation of PCRV
Thrombosis headache dizzy visual disturbance vertigo tinnitus IC
Amitryptiline A/E
Dry mouth
confusion
urinary retention
blurring vision
Myeloma presentation
C - Hypercalcaemia
R - Renal imparement (Free light chains)
A - Anaemia + Pancytopenia
B - Lytic bone lesions / Fractures / Vertebral collapse
Blood glucose measurements
Fasting > 5.5
Pre diabetes (5.6 - 7)
Random > 11
HbA1c > 48
6 in 1 vaccination
Diptheria tetanus polio Hep B Haemophilius influenzae B Whooping cough
Myeloproliferative disorders
- cells increased
- assosciated mutation
Haemopoetic stem cells –> Primary myelofibrosis
Erythroid cells –> PCV
Megakarocyte –> Essental thrombocythaemia
JAK2 MUTATION
Has the potential to cause AML
What are the Ab for Hashimotos thyroditis
Anti - thyroperoxidase Ab
Anti - thyroglobulin Ab
Causes of primary hypothyroid
Hashimotos
Iodine deficiency
Drug induced - lithium
Tx for hyperthyroidism
SSRI’s adverse effects
GI upset weight disturbance Hyponatraemia suicidal thoughts Prolong QT - Citalopram Increased risk of bleeding
Gastric ulcers
Pain when eating
Pain occurs 30mins - 1hr after a meal
Duodenal ulcer
Pain relieved by eating
Occurs 2-3hrs after meal
Night pain
Weight gain
TTP Presentation
Haemolytic anaemia decreased platelts AKI Headache / palsies / seizure - Neuro sx Fever Schistocytes
Exacerbation of COPD common organisms
- Haemophilius Influenzae
2. Strep pneumonia
Causes of hypoadrenalism
- Primary
- Secondary
- Addisons
- Surgery
- Infection
- Loss of blood flow
- Long term steroid usage
Gold standard Ix for Acromegaly
Oral glucose tolerance test
Carcinoid syndrome
- secretion
- presentation
- tx
Insulin / ACTH / Serotonin / Bradykinin
Bronchoconstriction
Hyperglycaemia
SST analogue
Prophlaxis for sickle cell crisis
Hydroxcarbamide
Tx for sideroblastic anaemia
Pyridoxine
Acute liver failure charecteristics
No previous liver disease
INR > 1.5
Onset < 26wks
Mental alteration - HE
Inheritance pattern for Haemophillia
X - lined recessive
COPD Tx pathway
SABA/SAMA
Asthma respose - LABA + ICS
NO Asthma response - LABA + LAMA
Oral theophlinne
Long term O2
Spinal cord compression presentation
UMN Sx - Below level of lesion
LMN Sx - At level of lesion
Describe Strep Pneumonia
Gram +ve diplococcus
Sensitivity
Proportion of pwople with a disease who test positive
Speicific
Proportion of people who don’t have the disease who test negative
+ve predicted value
Proportion of people who test +ve who have the condition
-ve predicted value
Proportion of people who test ive who don’t have the condition
Primary prevention
Decrease initial occurence
NHS Health check
Stain use
Immunisation
Secondary prevention
Tx disease to halt progression + prevent long term problems
Anti platelts post MI
Tertiary prevention
Reduce impact of the disease + improve QOL
Complicate UTI
Men children Pregnant woman Recurrent UTI Structural abnormality
WPWS ECG
Short PR interval
wide QRS
Delta wave
