Past paper Q's Flashcards

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1
Q

What bacteria are associated with periodontal disease?

A

P. gingivalis
Actinobacillus
Prevotella intermedia
Bacteroides forsythus

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2
Q

What bacteria are associated with dental caries?

A

Streptococcus Mutans
Actinomyces
Bifidobacterium
Lactobacillus and Veillonella

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3
Q

What bacteria are associated with root canal infections?

A

P. endontalis
Fusobacterium nucleatum

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4
Q

What are virulence factors?

A

A pathogens ability to infect or damage its host tissues is determined by the virulence factors
These are often molecules synthesised by the bacteria or virus and encoded by their genome, but may also be acquired from the environment via transmissible genetic elements

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5
Q

What antimicrobial is used to disinfect root canals?

A

Sodium Hypochlorite

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6
Q

What is the difference between candidosis and candidiasis?

A

Candidosis affects the mouth while candidasis has systemic effects

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7
Q

How is biofilm formed?

A

Adhesion - to surface via weak VDW forces. If not removed then anchor onto surface more permanently using cell adhesion structures
Colonisation - biofilms grows via cell division and recruitment
Accumulation
Complex community
Dispersal - biofilm spread and colonise new surfaces

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8
Q

What are the factors important for the growth of a colonisation?

A

Surface roughness
Whether surface is hydrophobic/philic

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9
Q

What are the 5 micro-organisms in candidosis?

A

Candida albicans
Candida glabrata
Candida tropicalis
Candida parapsilosis
Candida krusei

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10
Q

Which two organisms are resistant to fluconazole?

A

Candida glabrata
Candida krusei

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11
Q

What are the treatments for candidosis?

A

Topical antifungals such as nystatin, miconazole
Systemic antifungals, fluconazole
Chlorhexidine

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12
Q

Which two organisms are resistant to fluconazole?

A

Candida glabrata
Candida krusei

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13
Q

What is a niche?

A

Role of an organism in an environment

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14
Q

What is faculative anaerobic?

A

Usually respires aerobically but can respire anaerobically if no air present

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15
Q

What is obligately anaerobic?

A

Can only breathe anaerobically
It is harmed in the presence of oxygen

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16
Q

What gram stain is streptoccocus mutans?

A

Gram positive cocci

17
Q

Name 2 virulence factors for cariogenic bacteria?

A

Adhesions
Binding proteins
Sugar modifying enzymes
Polysaccharides
Acid tolerance and adaptation

18
Q

What are the virulence factors for periodontal microbes?

A

Gingipains
Adhesion molecules to firmly attach to root surface
Endotoxin LPS in cell membrane
Produces toxic byproducts

19
Q

List 3 of Koch postulates.

A

Pathogen is associated with the disease
Elimination or decreased numbers of pathogen results in return to health

20
Q

Why is miconazole used to treat angular cheilitis along with denture stomatitis?

A

Has anti-bacterial as well as antifungal properties
Angular cheilitis is infection by S Aureus