Passmed (Oct) Flashcards

1
Q

How do you treat uncomplicated Chlamydia?

A

Doxycycline, 100mg BD, 7 days

If pregnant - azithromycin / erythromycin / amoxicillin

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2
Q

Trichomonas vaginalis - microscopy?

A

Flagellated protozoa

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3
Q

How do you treat Trichomonas vaginalis?

A

Metronidazole

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4
Q

Complication of shoulder dystocia (plus features)?

A

Erb’s palsy - damage to the brachial plexus

Presents as adduction and internal rotation of the arm.

RFs - foetal macrosomia (birth weight >4kg)

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5
Q

Child presents to GP with honey-coloured crusted lesions on chin - Dx? treatment? how long before can go back to school?

A

Impetigo

Rx - topical hydrogen peroxide 1%

Can go back to school when lesions crusted and healed or 48hrs after starting abx

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6
Q

PPI side effects??

A

Usual - GI, N+V, dizziness
Other - insomnia, hypomagnesia (leading to hypocalcaemia and hypokalaemia)

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7
Q

Patient presents with right-sided hearing loss, vertigo and tinnitus. O/e there is an absent corneal reflex - Dx?

A

Vestibular schwannoma (acoustic neuroma)

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8
Q

Vestibular schwannoma (acoustic neuroma) can affect which cranial nerves?

A

cranial nerve VIII: vertigo, unilateral sensorineural hearing loss, unilateral tinnitus

cranial nerve V: absent corneal reflex

cranial nerve VII: facial palsy

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9
Q

What are the features of acute tubular necrosis?

A

Urinary Na >40
Urine osmolality <350
Poor response to fluid challenge
Normal serum urea:creatinine ratio
Brown granular casts

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10
Q

Women presents with multiple non-healing leg ulcers. She reports feeling generally unwell for many months. Examination findings include a blood pressure of 138/72 mmHg, pulse 90 bpm, pale conjunctivae and poor dentition associated with bleeding gums. Dx?

A

Vit C deficiency (scurvy)

Features:
gingivitis, loose teeth
poor wound healing
bleeding from gums, haematuria, epistaxis
general malaise

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11
Q

Osteoarthritis - X-ray signs?

A

‘LOSS’

loss of joint space (joint space narrowing)
osteophyte formation
sclerosis
subchondral cysts

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12
Q

What is Felty’s syndrome?

A

Triad of rheumatoid arthritis, splenomegaly and low WCC

Rare complication of RA

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13
Q

Temporal arteritis - Rx?

A

No vision loss = high dose pred

VIsion loss = IV methylpred

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14
Q

Anterior uveitis - presentation? Associations? Treatment?

A

Acute onset, red eye, ocular pain/discomfort, photophobia

Associated with HLA-B27 (ank spond, reactive arthritis etc)

Urgent ophthalmology review, cycloplegics (dilates the pupil which helps to relieve pain and photophobia) e.g. Atropine, cyclopentolate

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15
Q

Limited systemic sclerosis (CREST syndrome) - presentation?

A

Calcinosis
Raynaud’s phenomenon
oEsophageal dysmotility
Sclerodactyly
Telangiectasia

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16
Q

Patient presents with:
Pruritis (worst after taking showers or hot baths).
Tingling, burning, and numbness in arms, hands, and feet.
Headaches and lethargy.
Splenomegaly.
Elevated haemoglobin on full blood count
Dx??

A

Polycythaemia vera

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17
Q

Treatment of polycythaemia vera?

A

Venesection

Aspirin - reduce risk of thrombotic events

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18
Q

How do you treat hypomagnesaemia?

A

If <0.4 OR arrhythmias or seizures = IV magnesium

If >0.4 = oral magnesium salts (SE - diarrhoea)

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19
Q

What Ix should be carried out in someone with suspected multiple sclerosis?

A

MRI brain and spine without contrast

LP (oligoclonal bands)

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20
Q

If INR 5-8 - what do you do?

A

No bleeding - withhold warfarin for 1-2 says and restart on lower dose

Minor bleeding - stop warfarin, IV vit K, restart when INR below 5

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21
Q

What is the most common cause of infective endocarditis?

A

Staph aureus

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22
Q

What is the most common cause of infective endocarditis in a new valve replacement?

A

Staph epidermis

23
Q

What to do if INR >8

A

No bleeding - stop warfarin, oral vit K, repeat dose if INR still high after 24hrs, restart warfarin when INR <5

Minor bleeding - stop warfarin, IV vit K, repeat dose if INR still high after 24hrs, restart warfarin when INR <5

24
Q

Most commonly affected i]valve in infective endocarditis?

A

Mitral valve

Note: in IVDU is tricuspid

25
What test should be used if symptoms still persisting after H.pylori eradication?
Urea breath test
26
First line management of hepatic encephalopathy?
Lactulose (add rifaximin to prevent recurrence)
27
Classic triad in Budd-Chiari syndrome?
Sudden onset: Abdo pain Ascites Hepatomegaly
28
Live and neurological disease....?
Wilson's
29
Risk factors for Budd-Chiari syndrome?
COCP (20%) Pregnancy Polycythaemia vera Thrombophilia
30
Which area is most likely to be affected in ischaemic colitis?
Splenic flexure
31
Intestinal angina - triad?
Post-prandial abdominal pain Weight loss Abdominal bruit
32
Bronchiectasis and dextrocardia is suggestive of what?
Kartagener's syndrome
33
What are the indication for corticosteroid treatment in sarcoidosis?
Hypercalcaemia Uveitis Neuro involvement Cardiac involvement Parenchymal lung disease
34
Breast cancer tumour markers?
CA 15-3
35
What is the initial management of acute limb ischaemia?
Analgesia, IV heparin, vascular review
36
Addisonian crisis - treatment?
IV hydrocortisone
37
Prevention of Meniere's disease attacks?
Betahistine
38
If pregnant and had chickenpox exposure - how do you treat?
Urgently check varicella antibodies - if not immune.... <20 weeks = varicella immunoglobulins >20 weeks = oral acyclovir 7-14 days after exposure
39
Ix findings in Kallmann syndrome?
LH and FSH low - normal
40
Diabetes and HTN - first line treatment??
ACEi regardless of age eg Ramipril
41
Aortic stenosis - what medications are contraindicated?
Nitrates
42
Amlodipine drug type?
Calcium channel blocker
43
Raised ICP - Cushing's reflex?
Wide pulse pressure, bradycardia, irregular breathing
44
A 54-year-old woman presents to ophthalmology with a painful, red left eye and photophobia. On examination, you note a dendritic corneal ulcer. She has recently completed a course of oral prednisolone for an asthma exacerbation. Dx?
Herpes simplex keratitis (dendritic corneal ulcer) Rx - topical acyclovir
45
What cancer might myelodysplasia develop into?
AML
46
Schizophrenia - what prognostic factor is indicative of poor prognosis?
Gradual onset
47
What is the definition of 1 pack year?
20 cigarettes per day for one year
48
Ulcerative colitis - most commonly affected area?
Rectum
49
Symptoms of hypercalcaemia
painful bones, renal stones, abdominal groans and psychic moans
50
Bacterial vaginosis - treatment?
Oral metronidazole, 5-7days (even throughout pregnancy and breastfeeding)
51
At what age do febrile convulsions typically occur?
6 months - 5 years
52
What is Samter's triad?
Asthma, aspirin sensitivity, nasal polyps
53
Shaken baby syndrome - classic triad?
Retinal haemorrhages, subdural haematoma and encephalopathy
54
T2DM - target HbA1c?
48