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Oncology > Passmed > Flashcards

Passmed Flashcards

1
Q

Which cytotoxic agent can cause peripheral neuropathy?

A

Vincristine, vinblastine

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2
Q

What medication can be used for respiratory secretions?

A

Hyoscine bromide

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3
Q

Adverse effect of bleomycin?

A

Lung fibrosis

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4
Q

Side effects of doxorubicin?

A

Cardiomyopathy

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5
Q

Side effects of 5-fluorouracil

A

Myelosuppression
Mucositis
Dermatitis

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6
Q

Side effects of cisplatin

A

Ototoxicity
Peripheral neuropathy
Hypomagnesaemia

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7
Q

Raised beta-HCG and chorionic gonadotropin with a raised AFP

A

Non-seminomatous testicular cancer

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8
Q

AFP and seminoma?

A

If your AFP is raised its is afpsolutely not a seminoma

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9
Q

What cancers are associated with a raised AFP?

A

Liver cancer, teratoma

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10
Q

Which cancers are associated with S-100?

A

Melanoma, schwannoma

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11
Q

Which cancers are associated with bombesin?

A

Small cell lung cancer
Gastric cancer
Neuroblastoma

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12
Q

Oral morphine dosing vs subcut morphine dosing

A

Oral dose is double

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13
Q

Chemotherapy agent which can cause haemorrhagic cystitis

A

Cyclophosphamide

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14
Q

Adverse effects of cyclophosphamide

A

Haemorrhagic cystitis
Transitional cell cancer
Myelosuppression

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15
Q

Preferred opioids in patients with chronic kidney failure?

A

Alfentanil, fentanyl and buprenorphine

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16
Q

Cancers most likely to spread to the bones

A

Prostate
Breast
Lung

17
Q

If cancer spreads to the bone, where is it most likely to spread to?

A 
Spine
Pelvis
Ribs
Skull
Long bones
18
Q

Breast cancer tumour marker

A

CA15-3

19
Q

Most useful follow up investigations for teratoma?

A

AFP and beta-HCG

20
Q

Tell me about lung adenocarcinoma

A

Most common type in NON smokers

Usually a peripheral lesion

21
Q

Lung cancer but normal bronchoscopy?

A

Probably an adenocarcinoma –> occur in the peripheries

22
Q

This type of cancer is associated with PTH

A

Squamous cell

Increased PTH = hypercalcaemia

23
Q

This type of lung cancer is strongly associated with finger clubbing

A

Sqaumous cell cancer

24
Q

This type of lung cancer is strongly associated with hypertrophic pulmonary ostoearthropathy

A

Squamous cell cancer

25
Q

This type of lung cancer may secrete beta-HCG?

A

Large cell carinoma

26
Q

Side effects of methotrexate

A

Liver fibrosis, oral mucositis, myelosuppression

27
Q

Which medications should you use for nausea and vomiting in cancer

A

Metoclopramide
Ondansetron

(ondansetron can be especially effective if combined with dexamethasone)

28
Q

Treatment for hiccups in palliative care?

A

Chlorpromazine

Haloperidol

29
Q

Difference between hyoscine hydrobromide and hyoscine butylbromide?

A

Hyoscine HYDRObromide - used for respiratory secretions

Hyoscine butylBROmide - used for bowel colic

30
Q

What does a PET scan actually show?

A

Glucose uptake!

Oncology (2 decks)

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