Passmed

Question 1

Which cytotoxic agent can cause peripheral neuropathy?

Answer 1

Vincristine, vinblastine

Question 2

What medication can be used for respiratory secretions?

Answer 2

Hyoscine bromide

Question 3

Adverse effect of bleomycin?

Answer 3

Lung fibrosis

Question 4

Side effects of doxorubicin?

Answer 4

Cardiomyopathy

Question 5

Side effects of 5-fluorouracil

Answer 5

Myelosuppression
Mucositis
Dermatitis

Question 6

Side effects of cisplatin

Answer 6

Ototoxicity
Peripheral neuropathy
Hypomagnesaemia

Question 7

Raised beta-HCG and chorionic gonadotropin with a raised AFP

Answer 7

Non-seminomatous testicular cancer

Question 8

AFP and seminoma?

Answer 8

If your AFP is raised its is afpsolutely not a seminoma

Question 9

What cancers are associated with a raised AFP?

Answer 9

Liver cancer, teratoma

Question 10

Which cancers are associated with S-100?

Answer 10

Melanoma, schwannoma

Question 11

Which cancers are associated with bombesin?

Answer 11

Small cell lung cancer
Gastric cancer
Neuroblastoma

Question 12

Oral morphine dosing vs subcut morphine dosing

Answer 12

Oral dose is double

Question 13

Chemotherapy agent which can cause haemorrhagic cystitis

Answer 13

Cyclophosphamide

Question 14

Adverse effects of cyclophosphamide

Answer 14

Haemorrhagic cystitis
Transitional cell cancer
Myelosuppression

Question 15

Preferred opioids in patients with chronic kidney failure?

Answer 15

Alfentanil, fentanyl and buprenorphine

Question 16

Cancers most likely to spread to the bones

Answer 16

Prostate
Breast
Lung

Question 17

If cancer spreads to the bone, where is it most likely to spread to?

Answer 17

Spine
Pelvis
Ribs
Skull
Long bones

Question 18

Breast cancer tumour marker

Answer 18

CA15-3

Question 19

Most useful follow up investigations for teratoma?

Answer 19

AFP and beta-HCG

Question 20

Tell me about lung adenocarcinoma

Answer 20

Most common type in NON smokers

Usually a peripheral lesion

Question 21

Lung cancer but normal bronchoscopy?

Answer 21

Probably an adenocarcinoma –> occur in the peripheries

Question 22

This type of cancer is associated with PTH

Answer 22

Squamous cell

Increased PTH = hypercalcaemia

Question 23

This type of lung cancer is strongly associated with finger clubbing

Answer 23

Sqaumous cell cancer

Question 24

This type of lung cancer is strongly associated with hypertrophic pulmonary ostoearthropathy

Answer 24

Squamous cell cancer

Question 25

This type of lung cancer may secrete beta-HCG?

Answer 25

Large cell carinoma

Question 26

Side effects of methotrexate

Answer 26

Liver fibrosis, oral mucositis, myelosuppression

Question 27

Which medications should you use for nausea and vomiting in cancer

Answer 27

Metoclopramide Ondansetron (ondansetron can be especially effective if combined with dexamethasone)

Question 28

Treatment for hiccups in palliative care?

Answer 28

Chlorpromazine | Haloperidol

Question 29

Difference between hyoscine hydrobromide and hyoscine butylbromide?

Answer 29

Hyoscine HYDRObromide - used for respiratory secretions | Hyoscine butylBROmide - used for bowel colic

Question 30

What does a PET scan actually show?

Answer 30

Glucose uptake!