PassMed

Question 1

When do you gradually withdraw systemic corticosteroids?

Answer 1

*received >40mg daily for >1wk
*received >3wks of treatment
*recently received repeated courses

Question 2

How do you monitor for adverse effects of lithium therapy?

Answer 2

*lithium level every 3m
*U&Es every 6m
*TFTs every 6m

Question 3

Which drugs can lower seizure control?

Answer 3

*alcohol, cocaine, amphetamines
*ciprofloxacin, levofloxacin
*aminophylline, theophylline
*bupropion
*methylphenidate
*mefenamic acid

Question 4

Breastfeeding + antibiotic c/is

Answer 4

ciprofloxacin
tetracycline
chloramphenicol
sulphonamides

Question 5

Breastfeeding + psychiatric drug c/is

Answer 5

lithium
benzodiazepines

Question 6

Breastfeeding + other drug c/is

Answer 6

aspirin
carbimazole
methotrexate
sulfonylureas
cytotoxic drugs
amiodarone

Question 7

Oxygen therapy in critically ill patients

Answer 7

anaphylaxis, shock etc
reservoir mask at 15l/min

Question 8

Suspected bacterial meningitis - drug, dose, route

Answer 8

CEFTRIAXONE 2G IV STAT
CEFOTAXIME 2G IV STAT

Question 9

Sever oesophagitis - drug, dose, frequency

Answer 9

LANSOPRAZOLE 30MG PO OD
OMEPRAZOLE 40MG PO OD

Question 10

Patient with heart failure - c/is

Answer 10

pioglitazone
verapamil
NSAIDs
glucocorticoids
flecainide

Question 11

Paracetamol overdose management

Answer 11

Acetylcysteine is given if
*above/on treatment line
*staggered overdose
*8-24hr after ingestion of >150mg/kg
*>24hr late presentation if jaundiced/hepatic tenderness/++ALT

Question 12

Lithium dose range

Answer 12

0.4-1.0mmol/L

Question 13

verapamil s/es

Answer 13

heart failure
constipation
hypotension
bradycardia
flushing

Question 14

nifedipine/amlodipine/felodipine s/es

Answer 14

flushing
headache
ankle swelling

Question 15

Pregnancy + abx - c/is

Answer 15

tetracyclines
aminoglycosides
sulphonamides
trimethoprim
quinolones

Question 16

Pregnancy + other drugs - c/is

Answer 16

ACEi + angiotensin 2 receptor antagonists
statins
warfarin
sulfonylureas
retinoids (inc. topical)
cytotoxic agents

Question 17

Management of SVT

Answer 17

ADENOSINE 6MG IV STAT

Question 18

C DIFF infection - drug, dose, frequency

Answer 18

VANCOMYCIN 125MG QDS PO

Question 19

How to assess digoxin toxicity

Answer 19

ECG
U&Es

Question 20

Carbimazole monitoring

Answer 20

FBC - agranulocytosis and neutropenia are s/es
TFTs

Question 21

Drugs which decrease potassium

Answer 21

thiazide diuretics
loop diuretics
acetazolamide

Question 22

Drugs which increase potassium

Answer 22

ACEi
ARBs
spironolactone
K sparing diuretics
K supplements

Question 23

P450 inducers (INR goes down)

Answer 23

antiepileptics: phenytoin, carbamazepine
barbiturates: phenobarbitone
rifampicin
St John’s Wort
chronic alcohol intake
smoking

Question 24

P450 inhibitors (INR goes up)

Answer 24

abx: ciprofloxacin, clarithro/erythromycin
isoniazid
omeprazole
amiodarone
allopurinol
keto/fluconazole
SSRIs: fluoxetine, sertraline
sodium valproate
acute alcohol intake