Passage of action potential Flashcards
How is action potential similar to a Mexican wave?
Although wave of people standing up and raising their hands (action potential) moves around the stadium
People themselves do not move from seat to seat wtih wave (i.e do not physically pass around the stadium until they reach their orginal seat)
Instead their indvidiual actions of standing and raising their hands are stimulated by the action of the person on side of them are reproduced by person on the other side
Instructions of passage of action potnetial on unmyelinated axon
First step
At resting potential, the concentration of Na+ outside is high than inside, K+ is high on inside relative to outside
Overall concentration of positive ions, greater on outside making it positive compared to inside, axon is polarised
Mexican wave - equvialent to whole stadium seated at rest
Instructions of passage of action potnetial on unmyelinated axon
Second step
- Stimulus causes a sudden influex of Na+ hence a change on charge of axon membrane
- Action potential and membrane depolarised
- Mexican wave - a prompt leads to a vertical line of people to stand and wave their arms and stimulated into action
Instructions of passage of action potnetial on unmyelinated axon
Third step
- Localised of electrical current estbalished influex of Na+ opening voltage-gated channel a little further along axon - depolarisation
- Potassium ones open
- K+ began to leave the axon along the electrical chemical gradient , once initated the depolarisation moves along the membrane
- Mexican wave - sight of people standing and waving prompts the person to adjacent to seat to wave
Instructions of passage of action potnetial on unmyelinated axon
Fourth step
- Action potential (depolarisation) is propagated in the same way further along the axon
- The outward of movement of K+ ions have continued the extent of axon membrane behind the action potential has return to original ( + in outside , - on inside) - repolarisation
- Mexican wave - second line of people standing and waving prompts the third line of people to do the same
- Meanwhile first line resumed at original positions - re-seated
Instructions of passage of action potnetial on unmyelinated axon
Fifth step
- Repolarisation of axon allows Na+ ions to be actively transported out , once again returning the axon to its resting potential , readiness for new stimulus
- Mexican wave - people who have settle back in seats readjust themselves in readiness to repeat process when prompted to do so
What does myelin act around myelinated axon?
Act as an electrical insulator around axon
Prevents the action potentials from forming
Prevents depolarisation
Prepares the movement of ions in and out of membrane
What are the breaks between myelin called?
Nodes of Ranvier
Where can action potential occur in myelinated axon?
At nodes of Ranvier
What is saltatory conduction?
When an axon potential jumps between nodes of Ranvier
Advantages of salatory conduction?
- Speeds up transmission of nerve impulses
- Cytoplasm conducts enough electrical charge to depolarise the next node
Properties of node of Ranvier
- Gaps in myelin sheath
- Lots of Na+ and K+ ion channel
- Depolarisation can only happen at the nodes
- Action potential can jump between the nodes in process called salatory conduction