Pass Medicine Flashcards
which drugs should be used with caution in patients with asthma?
NSAIDs
BB
adenosine:
-
What Abx for Rx of exacerbations of chronic bronchitis?
Amoxicillin
Tetracycline
Clarithromycin
Abx for lower UTI
Trimethoprim
(nitrofurantoin)
Alternative : amox or cephalosporin
Abx for acute pyelonephritis
Broad spectrum cephalosporin (e.g. cefotaxime) or quinolone (e.g. cipro)
Abx for acute prostatitis
Quinolone (e.g. cipro) or trimethoprim
Abx uncomplicated community-acquired pneumonia
Amoxicillin (doxy or clarithromycin in penicillin allergic, add fluclox if staphylococci suspected e.g. in influenza)
Abx for pneumonia possible caused by atypical pathogens
Clarithromycin
Abx HAP
Within 5 days of admission: co-amox or cefuroxime
More than 5 days after admission: tazocin OR a broad spectrum cephalosporin (e.g. ceftazidime) OR a quinolone (e.g. cipro)
What pts are classified as needing a statin for secondary prevention of CV events?
& what dose
Known ischaemic heart disease OR
Cerebrovascular disease OR
Peripheral arterial disease
ATORVASTATIN 80MG OD
What pts are classified as needing a statin for primary prevention of CV events?
& what dose?
QRISK >/= 10%
OR
most T1DM
OR
CKD if eGFR <60
20 MG ATORVASTATIN (consider titrating up if non-HDL has not fallen by >= 40%)
What drug to treat cellulitis?
Fluclox
or if allergic, clarithromycin, erythromycin
Treatment of c/diff
oral Metronidazole 10-14 days
vanc
What is the WHO analgesic ladder?
Step 1: Non-opioid analgesics
- paracetamol
- non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin
Step 2 : Mild opioid analgesics
- codeine
- dihydrocodeine
Step 3 :Strong opioid
- analgesics
- morphine
Should you prescribe an anti-inflammatory to a pt already taking aspirin?
As the patient is already taking aspirin it is best to avoid anti-inflammatories. Prescribing an anti-inflammatory to a patient taking aspirin both negates the anti-platelet effect and increases the risk of gastrointestinal bleeding.
Rx for urgency incontinence
- Oxybutynin hydrochloride/
- Tolterodine tartrate/
- Darifenacin
(#1 CI in frail, older women)
start at lowest dose
Mirabegron if (the above) anticholinergics are CI
Rx for SVT
vasovagal manouvres
6mg adenosine (if no asthma)
if this fails
give 12 mg?
Classification of asthma attack
Moderate: PEFR 50-75% best or predicted Speech normal RR < 25 / min Pulse < 110 bpm
Severe: PEFR 33 - 50% best or predicted Can't complete sentences RR > 25/min Pulse > 110 bpm
Life-threatening: PEFR < 33% best or predicted Oxygen sats < 92% Silent chest, cyanosis or feeble respiratory effort Bradycardia, dysrhythmia or hypotension Exhaustion, confusion or coma
Rx severe asthma attack
high-flow oxygen
inhaled short-acting beta2 agonist (salbutamol)
steroid:
- either oral prednisolone or IV hydrocortisone
Ipratropium bromide is useful if the response to the above treatment is poor but it is not a first-line drug.
What time of day should you give the first dose of an antihypertensive?
at night
to avoid first-dose postural hypotension
Rx angina, already on GTN spray
BB, (if CI: CCB)
aspirin and statin (all pts with any form of CVD should take these)