Pass Med Flashcards
De Quervain’s Thyroiditis
Sub acute thyroiditis causing hyper then hypothyroidism
Cushing’s Syndrome - Acid base
Low K+, metabolic alkalosis
4 phases of Subacute thyroiditis (de quervain)
phase 1 (lasts 3-6 weeks): hyperthyroidism, painful goitre, raised ESR phase 2 (1-3 weeks): euthyroid phase 3 (weeks - months): hypothyroidism phase 4: thyroid structure and function goes back to normal
Sub Acute thyroiditis
3 characteristics
On USS scan
Following viral infection
= Tender goitre, hyperthyroidism and raised ESR
Decreased iodine uptake
Antibodies in Graves’ Disease
TSH receptor stimulating autoantibodies
Addisonian Crisis - Bloods
High K+
Low Sodium
Hypovolaemia
Hashimoto’s thyroiditis
- Antibodies
Anti thyroid perxoidase antibodies causing hypothyroidism
HbA1c Target - T2DM
Lifestyle
- 48
Monotherapy
- 48
- If rises to >58 then add another agent
Dual/Triple/Insulin
- 53
T2DM BP targets
No end organ damage
< 140/80
End organ damage
< 130/80
Acromegaly - Diagnostic test
Oral glucose tolerance test then GH measurements
In acromegaly, GH is not supressed by the Glucose (should be <2mu/L when pt is hyperglycaemic)
TFTs: Hyperthyroidism
Graves/toxic multinodular goitre
Low TSH
high Free T4
TFTs: Primary hypothyroidism
High TSH
Low T4
TFTs: Secondary hypothyroidism
Low TSH
Low T4
TFTs: Sick Euthyroid
Low TSH
Low T4
Common in hospital patients - caused by non-thyroid illness
TFTS: Subclinical Hypothryoidism
High TSH
Normal T4
