Pass Med Flashcards
Condition causing small bowel obstruction usually following acute cholecystitis
Gallstone Ileus
Primary Biliary Cholangitis
- Sx
Fatigue, pruitis, jaundice
PBC
- Bloods
High ALP and high cholesterol
PBC - Mx
Ursodeoxycholic Acid lifelong to prevent hepatic damage
Chrons: non-gastro signs
Arthritis, erythema nodosum, pyoderma gangrenosum
UC: non-gastro signs
Arthritis, erythema nodosum, pyoderma gangrenosum
PLUS:
Primary sclerosing cholangitis, uveitis
VIPoma?
Sx
Vasoactive Intestinal Peptide tumour = pancreatic mass and watery diarrhoea w/ low K+ and low Cl
B3 Niacin deficiency
Pellagra
- dermatitis, diarrhoea and cognitive deficit
e.g. Vegan
B1 Thiamine
Beri Beri
- Wernicke’s is a sub type of dry BeriBeri
Vit C
Scurvy: anaemia, bleeding gums, petichaie or bruising
Non-alcoholic fatty liver disease - who gets it? what test?
Obese w/ T2DM
Use enhanced liver fibrosis blood test
Aminosylicilates? Side effects?
Mesalazine/sulfasalazine
5-ASA
SE pancreatitis (mesal), nausea, vomiting, diarrhoea, exacerbation of colitis
Anti-scl-70 antibody
Scleroderma
ASMA antibody or P-ANCA
Primary sclerosing cholangitis
Anti-mitochrondrial antibody
Primary Biliary Cirrhosis
Anti CCP
Rheumatoid (with Rheumatoid factor)
Anti-saccharomyces cervisiaese
Present in Chron’s, not diagnostic
Urgent Endoscopy referral (2 week)
Dysphagia
Upper abdo mass
> 55 years with Weight loss and any of the following
- Upper abdo pain, reflux, dyspepsia
Non-urgent Endoscopy
Haematemesis
> 55 years
- treatment resistent dyspepsia,
- abdo pain + low Hb
- high platelet count
- N&V with weight loss/ GORD/dyspepsia/pain
Management if no need for referral
- Review meds
-life style advice - Full dose PPI for 1 month
OR - test and treat for H.pylori (before give PPI)
Anti-GBM antibody
Goodpasture’s disease
Anti-dsDNA
SLE
Primary sclerosing Cholangitis
80% UC patients will have PSC
- RUQ pain, fatigue, jaundice and pruritis
- ERCP diagnostics (beaded appearance)
Coeliac Disease - Complications
- Anaemia, folate, B12, iron deficiency,
- enteropathy-associated T-cell lymphoma
Osetoporosis, osteomalacia